Article Figures & Data
Figures
- FIGURE 1.
Results of in vivo 18F-FDS PET imaging. (A) Whole-body dynamic PET images in coronal view. High tracer secretion exclusively via kidneys and time-dependent increase of bladder activity are seen. (B) Dynamic right kidney images of transverse and coronal views. Rapid tracer accumulation in renal cortex and tracer transit into collecting system can be observed. (C) Examples of time–activity curves of kidneys (left) and bladder (right) assessed by dynamic PET imaging. %ID/cm3 = percentage injected dose per centimeter cubed.
Tables
- TABLE 1
Postmortem Tissue Counting in Rats at 10 Minutes, 30 Minutes, and 1 Hour After Injection of 18F-FDS and 99mTc-DTPA
18F-FDS 99mTc-DTPA Organ 10 min 30 min 1 h 10 min 30 min 1 h Blood 0.61 ± 0.16 0.38 ± 0.03* 0.15 ± 0.01* 0.84 ± 0.18 0.34 ± 0.03 0.09 ± 0.02 Liver 0.54 ± 0.10* 0.31 ± 0.03* 0.11 ± 0.01† 0.34 ± 0.09 0.15 ± 0.01 0.05 ± 0.01 Kidneys 1.77 ± 0.74 1.21 ± 0.09* 0.53 ± 0.21 2.51 ± 0.97 1.50 ± 0.18 0.77 ± 0.27 Intestine 0.17 ± 0.05 0.15 ± 0.02* 0.10 ± 0.01† 0.14 ± 0.03 0.08 ± 0.03 0.04 ± 0.01 Muscle 0.14 ± 0.04* 0.13 ± 0.03 0.05 ± 0.01* 0.20 ± 0.04 0.16 ± 0.04 0.02 ± 0.01 Spleen 0.18 ± 0.05 0.22 ± 0.01† 0.12 ± 0.01 0.16 ± 0.03 0.11 ± 0.01 0.10 ± 0.17 Stomach 0.08 ± 0.02 0.12 ± 0.06 0.03 ± 0.01 0.11 ± 0.03 0.12 ± 0.06 0.02 ± 0.01 Bone 0.14 ± 0.04 0.08 ± 0.01 0.05 ± 0.01† 0.15 ± 0.04 0.07 ± 0.02 0.02 ± 0.01 Heart 0.26 ± 0.07 0.21 ± 0.01* 0.13 ± 0.01* 0.30 ± 0.07 0.14 ± 0.01 0.05 ± 0.03 Lung 0.47 ± 0.16 0.34 ± 0.06 0.17 ± 0.02* 0.63 ± 0.24 0.31 ± 0.07 0.09 ± 0.06
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