Optimized Quantification of Translocator Protein Radioligand 18F-DPA-714 Uptake in the Brain of Genotyped Healthy Volunteers

Sonia Lavisse; Daniel García-Lorenzo; Marie-Anne Peyronneau; Benedetta Bodini; Claire Thiriez; Bertrand Kuhnast; Claude Comtat; Philippe Remy; Bruno Stankoff; Michel Bottlaender

doi:10.2967/jnumed.115.156083

Research ArticleClinical Investigations

Optimized Quantification of Translocator Protein Radioligand ¹⁸F-DPA-714 Uptake in the Brain of Genotyped Healthy Volunteers

Sonia Lavisse, Daniel García-Lorenzo, Marie-Anne Peyronneau, Benedetta Bodini, Claire Thiriez, Bertrand Kuhnast, Claude Comtat, Philippe Remy, Bruno Stankoff and Michel Bottlaender

Journal of Nuclear Medicine July 2015, 56 (7) 1048-1054; DOI: https://doi.org/10.2967/jnumed.115.156083

Sonia Lavisse

1CEA-DSV-I2BM, MIRCen, Fontenay-aux-Roses, France

2CNRS-UMR9199, Universités Paris-Sud and Paris-Saclay, Fontenay-aux-Roses, France

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Daniel García-Lorenzo

3Institut du Cerveau et de la Moelle épinière, Inserm-U1127 and Sorbonne University, UPMC-UMRS-1127, Paris, France

4CNRS-UMR7225, Paris, France

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Marie-Anne Peyronneau

5CEA-DSV-I2BM, SHFJ and IMIV, UMR1023 Inserm/CEA/Paris-Sud University, Orsay, France

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Benedetta Bodini

3Institut du Cerveau et de la Moelle épinière, Inserm-U1127 and Sorbonne University, UPMC-UMRS-1127, Paris, France

4CNRS-UMR7225, Paris, France

5CEA-DSV-I2BM, SHFJ and IMIV, UMR1023 Inserm/CEA/Paris-Sud University, Orsay, France

6Department of Neuroimaging, Institute of Psychiatry, King’s College London, London, England

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Claire Thiriez

1CEA-DSV-I2BM, MIRCen, Fontenay-aux-Roses, France

2CNRS-UMR9199, Universités Paris-Sud and Paris-Saclay, Fontenay-aux-Roses, France

7Neurology Department, Centre Expert Parkinson, CHU Henri Mondor, AP-HP, Créteil, France

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Bertrand Kuhnast

5CEA-DSV-I2BM, SHFJ and IMIV, UMR1023 Inserm/CEA/Paris-Sud University, Orsay, France

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Claude Comtat

5CEA-DSV-I2BM, SHFJ and IMIV, UMR1023 Inserm/CEA/Paris-Sud University, Orsay, France

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Philippe Remy

1CEA-DSV-I2BM, MIRCen, Fontenay-aux-Roses, France

2CNRS-UMR9199, Universités Paris-Sud and Paris-Saclay, Fontenay-aux-Roses, France

7Neurology Department, Centre Expert Parkinson, CHU Henri Mondor, AP-HP, Créteil, France

8Paris-Est University, Créteil, France; and

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Bruno Stankoff

3Institut du Cerveau et de la Moelle épinière, Inserm-U1127 and Sorbonne University, UPMC-UMRS-1127, Paris, France

4CNRS-UMR7225, Paris, France

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Michel Bottlaender

5CEA-DSV-I2BM, SHFJ and IMIV, UMR1023 Inserm/CEA/Paris-Sud University, Orsay, France

9CEA-DSV-I2BM, Neurospin, Gif-sur-Yvette, France

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Journal of Nuclear Medicine

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July 1, 2015

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Optimized Quantification of Translocator Protein Radioligand ¹⁸F-DPA-714 Uptake in the Brain of Genotyped Healthy Volunteers

Sonia Lavisse, Daniel García-Lorenzo, Marie-Anne Peyronneau, Benedetta Bodini, Claire Thiriez, Bertrand Kuhnast, Claude Comtat, Philippe Remy, Bruno Stankoff, Michel Bottlaender

Journal of Nuclear Medicine Jul 2015, 56 (7) 1048-1054; DOI: 10.2967/jnumed.115.156083

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Optimized Quantification of Translocator Protein Radioligand ¹⁸F-DPA-714 Uptake in the Brain of Genotyped Healthy Volunteers

Sonia Lavisse, Daniel García-Lorenzo, Marie-Anne Peyronneau, Benedetta Bodini, Claire Thiriez, Bertrand Kuhnast, Claude Comtat, Philippe Remy, Bruno Stankoff, Michel Bottlaender

Journal of Nuclear Medicine Jul 2015, 56 (7) 1048-1054; DOI: 10.2967/jnumed.115.156083

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Keywords

PET
18F-DPA-714
genotyped human
TSPO
quantification

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Optimized Quantification of Translocator Protein Radioligand ¹⁸F-DPA-714 Uptake in the Brain of Genotyped Healthy Volunteers

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