Phosphodiesterase 10A PET Radioligand Development Program: From Pig to Human

Christophe Plisson; David Weinzimmer; Steen Jakobsen; Sridhar Natesan; Cristian Salinas; Shu-Fei Lin; David Labaree; Ming-Qiang Zheng; Nabeel Nabulsi; Tiago Reis Marques; Shitij Kapur; Eiji Kawanishi; Takeaki Saijo; Roger N. Gunn; Richard E. Carson; Eugenii A. Rabiner

doi:10.2967/jnumed.113.131409

Research ArticleClinical Investigations

Phosphodiesterase 10A PET Radioligand Development Program: From Pig to Human

Christophe Plisson, David Weinzimmer, Steen Jakobsen, Sridhar Natesan, Cristian Salinas, Shu-Fei Lin, David Labaree, Ming-Qiang Zheng, Nabeel Nabulsi, Tiago Reis Marques, Shitij Kapur, Eiji Kawanishi, Takeaki Saijo, Roger N. Gunn, Richard E. Carson and Eugenii A. Rabiner

Journal of Nuclear Medicine April 2014, 55 (4) 595-601; DOI: https://doi.org/10.2967/jnumed.113.131409

Christophe Plisson

1Imanova Ltd., Centre for Imaging Sciences, Hammersmith Hospital, London, United Kingdom

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David Weinzimmer

2Yale University PET Center, Yale University School of Medicine, New Haven, Connecticut

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Steen Jakobsen

3Aarhus PET Centre, Aarhus Sygehus, Nørrebrogade, Aarhus C Denmark

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Sridhar Natesan

4Institute of Psychiatry, King’s College, London, United Kingdom

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Cristian Salinas

1Imanova Ltd., Centre for Imaging Sciences, Hammersmith Hospital, London, United Kingdom

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Shu-Fei Lin

2Yale University PET Center, Yale University School of Medicine, New Haven, Connecticut

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David Labaree

2Yale University PET Center, Yale University School of Medicine, New Haven, Connecticut

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Ming-Qiang Zheng

2Yale University PET Center, Yale University School of Medicine, New Haven, Connecticut

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Nabeel Nabulsi

2Yale University PET Center, Yale University School of Medicine, New Haven, Connecticut

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Tiago Reis Marques

4Institute of Psychiatry, King’s College, London, United Kingdom

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Shitij Kapur

4Institute of Psychiatry, King’s College, London, United Kingdom

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Eiji Kawanishi

5Medicinal Chemistry Research Laboratories I, Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Japan; and

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Takeaki Saijo

6DMPK Laboratories, Research Division, Mitsubishi Tanabe Pharma Corporation, Chiba, Japan

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Roger N. Gunn

1Imanova Ltd., Centre for Imaging Sciences, Hammersmith Hospital, London, United Kingdom

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Richard E. Carson

2Yale University PET Center, Yale University School of Medicine, New Haven, Connecticut

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Eugenii A. Rabiner

1Imanova Ltd., Centre for Imaging Sciences, Hammersmith Hospital, London, United Kingdom

5Medicinal Chemistry Research Laboratories I, Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Japan; and

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Journal of Nuclear Medicine

Vol. 55, Issue 4

April 1, 2014

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Phosphodiesterase 10A PET Radioligand Development Program: From Pig to Human

Journal of Nuclear Medicine Apr 2014, 55 (4) 595-601; DOI: 10.2967/jnumed.113.131409

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Phosphodiesterase 10A PET Radioligand Development Program: From Pig to Human

Journal of Nuclear Medicine Apr 2014, 55 (4) 595-601; DOI: 10.2967/jnumed.113.131409

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Keywords

PET
PDE10A
11C
in vivo
brain

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