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Research ArticleClinical Investigations

Phosphodiesterase 10A PET Radioligand Development Program: From Pig to Human

Christophe Plisson, David Weinzimmer, Steen Jakobsen, Sridhar Natesan, Cristian Salinas, Shu-Fei Lin, David Labaree, Ming-Qiang Zheng, Nabeel Nabulsi, Tiago Reis Marques, Shitij Kapur, Eiji Kawanishi, Takeaki Saijo, Roger N. Gunn, Richard E. Carson and Eugenii A. Rabiner
Journal of Nuclear Medicine April 2014, 55 (4) 595-601; DOI: https://doi.org/10.2967/jnumed.113.131409
Christophe Plisson
1Imanova Ltd., Centre for Imaging Sciences, Hammersmith Hospital, London, United Kingdom
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David Weinzimmer
2Yale University PET Center, Yale University School of Medicine, New Haven, Connecticut
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Steen Jakobsen
3Aarhus PET Centre, Aarhus Sygehus, Nørrebrogade, Aarhus C Denmark
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Sridhar Natesan
4Institute of Psychiatry, King’s College, London, United Kingdom
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Cristian Salinas
1Imanova Ltd., Centre for Imaging Sciences, Hammersmith Hospital, London, United Kingdom
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Shu-Fei Lin
2Yale University PET Center, Yale University School of Medicine, New Haven, Connecticut
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David Labaree
2Yale University PET Center, Yale University School of Medicine, New Haven, Connecticut
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Ming-Qiang Zheng
2Yale University PET Center, Yale University School of Medicine, New Haven, Connecticut
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Nabeel Nabulsi
2Yale University PET Center, Yale University School of Medicine, New Haven, Connecticut
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Tiago Reis Marques
4Institute of Psychiatry, King’s College, London, United Kingdom
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Shitij Kapur
4Institute of Psychiatry, King’s College, London, United Kingdom
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Eiji Kawanishi
5Medicinal Chemistry Research Laboratories I, Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Japan; and
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Takeaki Saijo
6DMPK Laboratories, Research Division, Mitsubishi Tanabe Pharma Corporation, Chiba, Japan
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Roger N. Gunn
1Imanova Ltd., Centre for Imaging Sciences, Hammersmith Hospital, London, United Kingdom
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Richard E. Carson
2Yale University PET Center, Yale University School of Medicine, New Haven, Connecticut
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Eugenii A. Rabiner
1Imanova Ltd., Centre for Imaging Sciences, Hammersmith Hospital, London, United Kingdom
5Medicinal Chemistry Research Laboratories I, Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Japan; and
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Article Information

vol. 55 no. 4 595-601
DOI 
https://doi.org/10.2967/jnumed.113.131409
PubMed 
24614221

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication August 22, 2013
  • Accepted for publication November 4, 2013
  • Published online April 1, 2014.

Article Versions

  • previous version (March 10, 2014 - 07:07).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2014 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Author Information

  1. Christophe Plisson1,
  2. David Weinzimmer2,
  3. Steen Jakobsen3,
  4. Sridhar Natesan4,
  5. Cristian Salinas1,
  6. Shu-Fei Lin2,
  7. David Labaree2,
  8. Ming-Qiang Zheng2,
  9. Nabeel Nabulsi2,
  10. Tiago Reis Marques4,
  11. Shitij Kapur4,
  12. Eiji Kawanishi5,
  13. Takeaki Saijo6,
  14. Roger N. Gunn1,
  15. Richard E. Carson2 and
  16. Eugenii A. Rabiner1,5
  1. 1Imanova Ltd., Centre for Imaging Sciences, Hammersmith Hospital, London, United Kingdom
  2. 2Yale University PET Center, Yale University School of Medicine, New Haven, Connecticut
  3. 3Aarhus PET Centre, Aarhus Sygehus, Nørrebrogade, Aarhus C Denmark
  4. 4Institute of Psychiatry, King’s College, London, United Kingdom
  5. 5Medicinal Chemistry Research Laboratories I, Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Japan; and
  6. 6DMPK Laboratories, Research Division, Mitsubishi Tanabe Pharma Corporation, Chiba, Japan
  1. For correspondence or reprints contact: Christophe Plisson, Imanova Ltd., Burlington Danes Bldg., Hammersmith Hospital, Du Cane Rd., London W12 0NN, U.K. E-mail: christophe.plisson{at}imanova.co.uk
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Journal of Nuclear Medicine: 55 (4)
Journal of Nuclear Medicine
Vol. 55, Issue 4
April 1, 2014
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Phosphodiesterase 10A PET Radioligand Development Program: From Pig to Human
Christophe Plisson, David Weinzimmer, Steen Jakobsen, Sridhar Natesan, Cristian Salinas, Shu-Fei Lin, David Labaree, Ming-Qiang Zheng, Nabeel Nabulsi, Tiago Reis Marques, Shitij Kapur, Eiji Kawanishi, Takeaki Saijo, Roger N. Gunn, Richard E. Carson, Eugenii A. Rabiner
Journal of Nuclear Medicine Apr 2014, 55 (4) 595-601; DOI: 10.2967/jnumed.113.131409

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Phosphodiesterase 10A PET Radioligand Development Program: From Pig to Human
Christophe Plisson, David Weinzimmer, Steen Jakobsen, Sridhar Natesan, Cristian Salinas, Shu-Fei Lin, David Labaree, Ming-Qiang Zheng, Nabeel Nabulsi, Tiago Reis Marques, Shitij Kapur, Eiji Kawanishi, Takeaki Saijo, Roger N. Gunn, Richard E. Carson, Eugenii A. Rabiner
Journal of Nuclear Medicine Apr 2014, 55 (4) 595-601; DOI: 10.2967/jnumed.113.131409
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