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Journal of Nuclear Medicine

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Research ArticleBasic Science Investigations

XTEN-Annexin A5: XTEN Allows Complete Expression of Long-Circulating Protein-Based Imaging Probes as Recombinant Alternative to PEGylation

Akvile Haeckel, Franziska Appler, Lena Figge, Harald Kratz, Mathias Lukas, Roger Michel, Jörg Schnorr, Marietta Zille, Bernd Hamm and Eyk Schellenberger
Journal of Nuclear Medicine March 2014, 55 (3) 508-514; DOI: https://doi.org/10.2967/jnumed.113.128108
Akvile Haeckel
1Institute of Radiology—Molecular Imaging Group, Charité, Berlin, Germany
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Franziska Appler
1Institute of Radiology—Molecular Imaging Group, Charité, Berlin, Germany
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Lena Figge
1Institute of Radiology—Molecular Imaging Group, Charité, Berlin, Germany
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Harald Kratz
1Institute of Radiology—Molecular Imaging Group, Charité, Berlin, Germany
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Mathias Lukas
2Clinic of Nuclear Medicine, Charité, Berlin, Germany; and
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Roger Michel
2Clinic of Nuclear Medicine, Charité, Berlin, Germany; and
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Jörg Schnorr
1Institute of Radiology—Molecular Imaging Group, Charité, Berlin, Germany
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Marietta Zille
3Clinic of Neurology—Department of Experimental Neurology, Charité, Berlin, Germany
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Bernd Hamm
1Institute of Radiology—Molecular Imaging Group, Charité, Berlin, Germany
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Eyk Schellenberger
1Institute of Radiology—Molecular Imaging Group, Charité, Berlin, Germany
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Journal of Nuclear Medicine: 55 (3)
Journal of Nuclear Medicine
Vol. 55, Issue 3
March 1, 2014
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XTEN-Annexin A5: XTEN Allows Complete Expression of Long-Circulating Protein-Based Imaging Probes as Recombinant Alternative to PEGylation
Akvile Haeckel, Franziska Appler, Lena Figge, Harald Kratz, Mathias Lukas, Roger Michel, Jörg Schnorr, Marietta Zille, Bernd Hamm, Eyk Schellenberger
Journal of Nuclear Medicine Mar 2014, 55 (3) 508-514; DOI: 10.2967/jnumed.113.128108

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XTEN-Annexin A5: XTEN Allows Complete Expression of Long-Circulating Protein-Based Imaging Probes as Recombinant Alternative to PEGylation
Akvile Haeckel, Franziska Appler, Lena Figge, Harald Kratz, Mathias Lukas, Roger Michel, Jörg Schnorr, Marietta Zille, Bernd Hamm, Eyk Schellenberger
Journal of Nuclear Medicine Mar 2014, 55 (3) 508-514; DOI: 10.2967/jnumed.113.128108
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Keywords

  • XTEN
  • polyethylene glycol
  • annexin A5
  • long-circulating
  • recombinant protein
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