Development of 124I Immuno-PET Targeting Tumor Vascular TEM1/Endosialin

Ann-Marie Chacko; Chunsheng Li; Madhura Nayak; John L. Mikitsh; Jia Hu; Catherine Hou; Luigi Grasso; Nicholas C. Nicolaides; Vladimir R. Muzykantov; Chaitanya R. Divgi; George Coukos

doi:10.2967/jnumed.113.121905

Research ArticleBasic Science Investigations

Development of ¹²⁴I Immuno-PET Targeting Tumor Vascular TEM1/Endosialin

Ann-Marie Chacko, Chunsheng Li, Madhura Nayak, John L. Mikitsh, Jia Hu, Catherine Hou, Luigi Grasso, Nicholas C. Nicolaides, Vladimir R. Muzykantov, Chaitanya R. Divgi and George Coukos

Journal of Nuclear Medicine March 2014, 55 (3) 500-507; DOI: https://doi.org/10.2967/jnumed.113.121905

Ann-Marie Chacko

1Division of Nuclear Medicine and Clinical Molecular Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

2Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

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Chunsheng Li

3Ovarian Cancer Research Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; and

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Madhura Nayak

1Division of Nuclear Medicine and Clinical Molecular Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

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John L. Mikitsh

1Division of Nuclear Medicine and Clinical Molecular Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

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Jia Hu

3Ovarian Cancer Research Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; and

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Catherine Hou

1Division of Nuclear Medicine and Clinical Molecular Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

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Luigi Grasso

4Morphotek, Inc., Exton, Pennsylvania

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Nicholas C. Nicolaides

4Morphotek, Inc., Exton, Pennsylvania

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Vladimir R. Muzykantov

2Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

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Chaitanya R. Divgi

1Division of Nuclear Medicine and Clinical Molecular Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

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George Coukos

3Ovarian Cancer Research Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; and

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Journal of Nuclear Medicine

Vol. 55, Issue 3

March 1, 2014

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Development of ¹²⁴I Immuno-PET Targeting Tumor Vascular TEM1/Endosialin

Ann-Marie Chacko, Chunsheng Li, Madhura Nayak, John L. Mikitsh, Jia Hu, Catherine Hou, Luigi Grasso, Nicholas C. Nicolaides, Vladimir R. Muzykantov, Chaitanya R. Divgi, George Coukos

Journal of Nuclear Medicine Mar 2014, 55 (3) 500-507; DOI: 10.2967/jnumed.113.121905

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Development of ¹²⁴I Immuno-PET Targeting Tumor Vascular TEM1/Endosialin

Ann-Marie Chacko, Chunsheng Li, Madhura Nayak, John L. Mikitsh, Jia Hu, Catherine Hou, Luigi Grasso, Nicholas C. Nicolaides, Vladimir R. Muzykantov, Chaitanya R. Divgi, George Coukos

Journal of Nuclear Medicine Mar 2014, 55 (3) 500-507; DOI: 10.2967/jnumed.113.121905

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Keywords

immuno-PET
TEM1
endosialin
MORAb-004
Monoclonal Antibodies

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