188Re-ZHER2:V2, a Promising Affibody-Based Targeting Agent Against HER2-Expressing Tumors: Preclinical Assessment

Mohamed Altai; Helena Wållberg; Hadis Honarvar; Joanna Strand; Anna Orlova; Zohreh Varasteh; Mattias Sandström; John Löfblom; Erik Larsson; Sven-Erik Strand; Mark Lubberink; Stefan Ståhl; Vladimir Tolmachev

doi:10.2967/jnumed.114.140194

Research ArticleBasic Science Investigations

¹⁸⁸Re-Z_HER2:V2, a Promising Affibody-Based Targeting Agent Against HER2-Expressing Tumors: Preclinical Assessment

Mohamed Altai, Helena Wållberg, Hadis Honarvar, Joanna Strand, Anna Orlova, Zohreh Varasteh, Mattias Sandström, John Löfblom, Erik Larsson, Sven-Erik Strand, Mark Lubberink, Stefan Ståhl and Vladimir Tolmachev

Journal of Nuclear Medicine November 2014, 55 (11) 1842-1848; DOI: https://doi.org/10.2967/jnumed.114.140194

Mohamed Altai

1Division of Biomedical Radiation Sciences, Uppsala University, Uppsala, Sweden

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Helena Wållberg

2Division of Protein Technology, School of Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden

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Hadis Honarvar

1Division of Biomedical Radiation Sciences, Uppsala University, Uppsala, Sweden

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Joanna Strand

1Division of Biomedical Radiation Sciences, Uppsala University, Uppsala, Sweden

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Anna Orlova

3Preclinical PET Platform, Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden

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Zohreh Varasteh

3Preclinical PET Platform, Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden

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Mattias Sandström

4Nuclear Medicine and PET, Uppsala University, Uppsala, Sweden

5Medical Physics, Uppsala University Hospital, Uppsala, Sweden; and

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John Löfblom

2Division of Protein Technology, School of Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden

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Erik Larsson

6Medical Radiation Physics, Clinical Sciences, Lund University, Lund, Sweden

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Sven-Erik Strand

6Medical Radiation Physics, Clinical Sciences, Lund University, Lund, Sweden

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Mark Lubberink

4Nuclear Medicine and PET, Uppsala University, Uppsala, Sweden

5Medical Physics, Uppsala University Hospital, Uppsala, Sweden; and

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Stefan Ståhl

2Division of Protein Technology, School of Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden

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Vladimir Tolmachev

1Division of Biomedical Radiation Sciences, Uppsala University, Uppsala, Sweden

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November 1, 2014

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¹⁸⁸Re-Z_HER2:V2, a Promising Affibody-Based Targeting Agent Against HER2-Expressing Tumors: Preclinical Assessment

Journal of Nuclear Medicine Nov 2014, 55 (11) 1842-1848; DOI: 10.2967/jnumed.114.140194

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¹⁸⁸Re-Z_HER2:V2, a Promising Affibody-Based Targeting Agent Against HER2-Expressing Tumors: Preclinical Assessment

Journal of Nuclear Medicine Nov 2014, 55 (11) 1842-1848; DOI: 10.2967/jnumed.114.140194

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Keywords

HER2
Affibody molecule
188Re
dosimetry

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