Longitudinal Amyloid Imaging in Mouse Brain with 11C-PIB: Comparison of APP23, Tg2576, and APPswe-PS1dE9 Mouse Models of Alzheimer Disease

Anniina Snellman; Francisco R. López-Picón; Johanna Rokka; Mario Salmona; Gianluigi Forloni; Mika Scheinin; Olof Solin; Juha O. Rinne; Merja Haaparanta-Solin

doi:10.2967/jnumed.112.110163

Research ArticleBasic Science Investigations

Longitudinal Amyloid Imaging in Mouse Brain with ¹¹C-PIB: Comparison of APP23, Tg2576, and APP_swe-PS1_dE9 Mouse Models of Alzheimer Disease

Anniina Snellman, Francisco R. López-Picón, Johanna Rokka, Mario Salmona, Gianluigi Forloni, Mika Scheinin, Olof Solin, Juha O. Rinne and Merja Haaparanta-Solin

Journal of Nuclear Medicine August 2013, 54 (8) 1434-1441; DOI: https://doi.org/10.2967/jnumed.112.110163

Anniina Snellman

1MediCity/PET Preclinical Laboratory, University of Turku, Turku PET Centre, Turku, Finland

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Francisco R. López-Picón

1MediCity/PET Preclinical Laboratory, University of Turku, Turku PET Centre, Turku, Finland

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Johanna Rokka

2Radiopharmaceutical Chemistry Laboratory, University of Turku, Turku PET Centre, Turku, Finland

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Mario Salmona

3Mario Negri Institute for Pharmacological Research, Milan, Italy

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Gianluigi Forloni

3Mario Negri Institute for Pharmacological Research, Milan, Italy

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Mika Scheinin

4Department of Pharmacology, Drug Development, and Therapeutics, University of Turku, and Unit of Clinical Pharmacology, Turku University Hospital, Turku, Finland

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Olof Solin

2Radiopharmaceutical Chemistry Laboratory, University of Turku, Turku PET Centre, Turku, Finland

5Accelerator Laboratory, Åbo Akademi University, Turku PET Centre, Turku, Finland; and

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Juha O. Rinne

6Turku PET Centre, University of Turku, Turku University Hospital, Turku, Finland

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Merja Haaparanta-Solin

1MediCity/PET Preclinical Laboratory, University of Turku, Turku PET Centre, Turku, Finland

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Journal of Nuclear Medicine

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August 1, 2013

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Longitudinal Amyloid Imaging in Mouse Brain with ¹¹C-PIB: Comparison of APP23, Tg2576, and APP_swe-PS1_dE9 Mouse Models of Alzheimer Disease

Anniina Snellman, Francisco R. López-Picón, Johanna Rokka, Mario Salmona, Gianluigi Forloni, Mika Scheinin, Olof Solin, Juha O. Rinne, Merja Haaparanta-Solin

Journal of Nuclear Medicine Aug 2013, 54 (8) 1434-1441; DOI: 10.2967/jnumed.112.110163

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Longitudinal Amyloid Imaging in Mouse Brain with ¹¹C-PIB: Comparison of APP23, Tg2576, and APP_swe-PS1_dE9 Mouse Models of Alzheimer Disease

Anniina Snellman, Francisco R. López-Picón, Johanna Rokka, Mario Salmona, Gianluigi Forloni, Mika Scheinin, Olof Solin, Juha O. Rinne, Merja Haaparanta-Solin

Journal of Nuclear Medicine Aug 2013, 54 (8) 1434-1441; DOI: 10.2967/jnumed.112.110163

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Keywords

Alzheimer disease
Amyloid Imaging
Positron Emission Tomography
11C-PIB, Pittsburgh compound B

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Longitudinal Amyloid Imaging in Mouse Brain with ¹¹C-PIB: Comparison of APP23, Tg2576, and APP_swe-PS1_dE9 Mouse Models of Alzheimer Disease

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