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Research ArticleBasic Science Investigations

Quantification of Brain Glucose Metabolism by 18F-FDG PET with Real-Time Arterial and Image-Derived Input Function in Mice

Malte F. Alf, Matthias T. Wyss, Alfred Buck, Bruno Weber, Roger Schibli and Stefanie D. Krämer
Journal of Nuclear Medicine January 2013, 54 (1) 132-138; DOI: https://doi.org/10.2967/jnumed.112.107474
Malte F. Alf
1Center for Radiopharmaceutical Sciences of ETH, PSI, and USZ, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland
2Laboratory of Functional and Metabolic Imaging, Institute of Physics of Biological Systems, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
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Matthias T. Wyss
3Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland
4Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland; and
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Alfred Buck
3Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland
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Bruno Weber
4Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland; and
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Roger Schibli
1Center for Radiopharmaceutical Sciences of ETH, PSI, and USZ, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland
5Center for Radiopharmaceutical Sciences of ETH, PSI, and USZ, Paul Scherrer Institute PSI, Villigen, Switzerland
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Stefanie D. Krämer
1Center for Radiopharmaceutical Sciences of ETH, PSI, and USZ, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland
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Article Information

vol. 54 no. 1 132-138
DOI 
https://doi.org/10.2967/jnumed.112.107474
PubMed 
23160788

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication April 14, 2012
  • Accepted for publication July 27, 2012
  • Published online January 2, 2013.

Article Versions

  • previous version (November 15, 2012 - 08:55).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2013 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Author Information

  1. Malte F. Alf1,2,
  2. Matthias T. Wyss3,4,
  3. Alfred Buck3,
  4. Bruno Weber4,
  5. Roger Schibli1,5 and
  6. Stefanie D. Krämer1
  1. 1Center for Radiopharmaceutical Sciences of ETH, PSI, and USZ, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland
  2. 2Laboratory of Functional and Metabolic Imaging, Institute of Physics of Biological Systems, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
  3. 3Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland
  4. 4Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland; and
  5. 5Center for Radiopharmaceutical Sciences of ETH, PSI, and USZ, Paul Scherrer Institute PSI, Villigen, Switzerland
  1. For correspondence or reprints contact either of the following: Stefanie Krämer, Center for Radiopharmaceutical Sciences of ETH, PSI, and USZ, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Wolfgang-Pauli-Strasse 10, CH-8093 Zurich, Switzerland. E-mail: stefanie.kraemer{at}pharma.ethz.ch
  2. Roger Schibli, Center for Radiopharmaceutical Sciences of ETH, PSI, and USZ, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Wolfgang-Pauli-Strasse 10, CH-8093 Zurich, Switzerland. E-mail: roger.schibli{at}pharma.ethz.ch
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Journal of Nuclear Medicine: 54 (1)
Journal of Nuclear Medicine
Vol. 54, Issue 1
January 1, 2013
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Quantification of Brain Glucose Metabolism by 18F-FDG PET with Real-Time Arterial and Image-Derived Input Function in Mice
Malte F. Alf, Matthias T. Wyss, Alfred Buck, Bruno Weber, Roger Schibli, Stefanie D. Krämer
Journal of Nuclear Medicine Jan 2013, 54 (1) 132-138; DOI: 10.2967/jnumed.112.107474

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Quantification of Brain Glucose Metabolism by 18F-FDG PET with Real-Time Arterial and Image-Derived Input Function in Mice
Malte F. Alf, Matthias T. Wyss, Alfred Buck, Bruno Weber, Roger Schibli, Stefanie D. Krämer
Journal of Nuclear Medicine Jan 2013, 54 (1) 132-138; DOI: 10.2967/jnumed.112.107474
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