Skip to main content

Main menu

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
    • Continuing Education
    • JNM Podcasts
  • Subscriptions
    • Subscribers
    • Institutional and Non-member
    • Rates
    • Journal Claims
    • Corporate & Special Sales
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI

User menu

  • Subscribe
  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Nuclear Medicine
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI
  • Subscribe
  • My alerts
  • Log in
  • My Cart
Journal of Nuclear Medicine

Advanced Search

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
    • Continuing Education
    • JNM Podcasts
  • Subscriptions
    • Subscribers
    • Institutional and Non-member
    • Rates
    • Journal Claims
    • Corporate & Special Sales
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • View or Listen to JNM Podcast
  • Visit JNM on Facebook
  • Join JNM on LinkedIn
  • Follow JNM on Twitter
  • Subscribe to our RSS feeds
Research ArticleBasic Science Investigations

5-(2-18F-Fluoroethoxy)-l-Tryptophan as a Substrate of System L Transport for Tumor Imaging by PET

Stefanie D. Krämer, Linjing Mu, Adrienne Müller, Claudia Keller, Olga F. Kuznetsova, Christian Schweinsberg, Dominic Franck, Cristina Müller, Tobias L. Ross, Roger Schibli and Simon M. Ametamey
Journal of Nuclear Medicine March 2012, 53 (3) 434-442; DOI: https://doi.org/10.2967/jnumed.111.096289
Stefanie D. Krämer
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Linjing Mu
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Adrienne Müller
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Claudia Keller
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Olga F. Kuznetsova
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Christian Schweinsberg
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Dominic Franck
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Cristina Müller
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tobias L. Ross
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Roger Schibli
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Simon M. Ametamey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • PDF
Loading

Article Information

vol. 53 no. 3 434-442
DOI 
https://doi.org/10.2967/jnumed.111.096289
PubMed 
22331220

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication August 8, 2011
  • Accepted for publication October 25, 2011
  • Published online March 5, 2012.

Article Versions

  • previous version (February 13, 2012 - 08:17).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2012 by the Society of Nuclear Medicine, Inc.

Author Information

  1. Stefanie D. Krämer1,
  2. Linjing Mu2,
  3. Adrienne Müller1,
  4. Claudia Keller1,
  5. Olga F. Kuznetsova1,3,
  6. Christian Schweinsberg2,
  7. Dominic Franck1,
  8. Cristina Müller4,
  9. Tobias L. Ross1,
  10. Roger Schibli1,4 and
  11. Simon M. Ametamey1
  1. 1Center for Radiopharmaceutical Sciences ETH-PSI-USZ, Institute of Pharmaceutical Sciences ETH, Zurich, Switzerland
  2. 2Center for Radiopharmaceutical Sciences ETH-PSI-USZ, Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland
  3. 3N.P. Bechtereva Institute of Human Brain RAS, Russian Academy of Science, St. Petersburg, Russia; and
  4. 4Center for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, Villigen, Switzerland
  1. For correspondence contact: Stefanie D. Krämer, Center for Radiopharmaceutical Sciences ETH-PSI-USZ, Institute of Pharmaceutical Sciences, Wolfgang-Pauli-Strasse 10, CH-8093 Zurich, Switzerland. E-mail: stefanie.kraemer{at}pharma.ethz.ch
View Full Text

Statistics from Altmetric.com

Cited By...

  • 45 Citations
  • 44 Citations
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • The SLC3 and SLC7 families of amino acid transporters
    Dimitrios Fotiadis, Yoshikatsu Kanai, Manuel Palacín
    Molecular Aspects of Medicine 2013 34 2-3
  • Comparison of Amino Acid Positron Emission Tomographic Radiotracers for Molecular Imaging of Primary and Metastatic Brain Tumors
    Csaba Juhász, Shalini Dwivedi, David O. Kamson, Sharon K. Michelhaugh, Sandeep Mittal
    Molecular Imaging 2014 13 6
  • 18F-Fluorodihydroxyphenylalanine PET/CT in Patients with Neuroendocrine Tumors of Unknown Origin: Relation to Tumor Origin and Differentiation
    Alessio Imperiale, Edmond Rust, Sophie Gabriel, Julien Detour, Bernard Goichot, Bernard Duclos, Jean-Emmanuel Kurtz, Philippe Bachellier, Izzie-Jacques Namer, David Taïeb
    Journal of Nuclear Medicine 2014 55 3
  • Epileptic Activity Increases Cerebral Amino Acid Transport Assessed by 18F-Fluoroethyl-l-Tyrosine Amino Acid PET: A Potential Brain Tumor Mimic
    Markus Hutterer, Yvonne Ebner, Markus J. Riemenschneider, Antje Willuweit, Mark McCoy, Barbara Egger, Michael Schröder, Christina Wendl, Dirk Hellwig, Jirka Grosse, Karin Menhart, Martin Proescholdt, Brita Fritsch, Horst Urbach, Guenther Stockhammer, Ulrich Roelcke, Norbert Galldiks, Philipp T. Meyer, Karl-Josef Langen, Peter Hau, Eugen Trinka
    Journal of Nuclear Medicine 2017 58 1
  • LAT1-Targeting Thermoresponsive Liposomes for Effective Cellular Uptake by Cancer Cells
    Minami Maekawa-Matsuura, Kei Fujieda, Yutaro Maekawa, Tomohiro Nishimura, Kenichi Nagase, Hideko Kanazawa
    ACS Omega 2019 4 4
  • 2-[18F]Fluoroethyl tosylate – a versatile tool for building18F-based radiotracers for positron emission tomography
    Torsten Kniess, Markus Laube, Peter Brust, Jörg Steinbach
    MedChemComm 2015 6 10
  • Improved Radiosynthesis and Biological Evaluations of L- and D-1-[18F]Fluoroethyl-Tryptophan for PET Imaging of IDO-Mediated Kynurenine Pathway of Tryptophan Metabolism
    Yangchun Xin, Hancheng Cai
    Molecular Imaging and Biology 2017 19 4
  • Cyclopentadienyl-Based Amino Acids (Cp-aa) As Phenylalanine Analogues for Tumor Targeting: Syntheses and Biological Properties of [(Cp-aa)M(CO)3](M = Mn, Re, 99mTc)
    Samer Sulieman, Daniel Can, John Mertens, Harmel W. Peindy N’Dongo, Yu Liu, Paul Schmutz, Matthias Bauwens, Bernhard Spingler, Roger Alberto
    Organometallics 2012 31 19
  • Preparation of No‐Carrier‐Added 6‐[18F]Fluoro‐l‐tryptophan via Cu‐Mediated Radiofluorination
    Dominique Schäfer, Philipp Weiß, Johannes Ermert, Johnny Castillo Meleán, Fadi Zarrad, Bernd Neumaier
    European Journal of Organic Chemistry 2016 2016 27
  • Synthesis and biological evaluation of 18F-labeled fluoropropyl tryptophan analogs as potential PET probes for tumor imaging
    Aristeidis Chiotellis, Linjing Mu, Adrienne Müller, Svetlana V. Selivanova, Claudia Keller, Roger Schibli, Stefanie D. Krämer, Simon M. Ametamey
    European Journal of Medicinal Chemistry 2013 70

Article usage

Article usage: February 2012 to April 2025

AbstractFullPdf
Feb 2012284037
Mar 201211712891
Apr 20123472239
May 20122272535
Jun 20121401221
Jul 2012121817
Aug 2012104929
Sep 20121134443
Oct 2012782345
Nov 20121005564
Dec 2012884430
Jan 2013553839
Feb 2013874134
Mar 2013932025
Apr 2013382124
May 2013934425
Jun 2013434023
Jul 2013261111
Aug 2013331217
Sep 2013411829
Oct 2013512623
Nov 2013222520
Dec 2013511623
Jan 2014301228
Feb 2014321331
Mar 2014281825
Apr 2014142625
May 2014231028
Jun 2014291124
Jul 2014261216
Aug 201410810
Sep 2014343420
Oct 2014351825
Nov 2014191810
Dec 201427912
Jan 2015121311
Feb 2015261714
Mar 2015381639
Apr 2015171116
May 2015222213
Jun 201562113
Jul 2015231018
Aug 2015201513
Sep 2015232017
Oct 2015221513
Nov 20151859
Dec 2015311511
Jan 2016221516
Feb 2016252423
Mar 201619824
Apr 2016181432
May 2016271719
Jun 20161899
Jul 2016201430
Aug 20168138
Sep 201616515
Oct 2016151119
Nov 201621159
Dec 201615821
Jan 201721820
Feb 201715817
Mar 2017171319
Apr 2017331626
May 201734817
Jun 2017211318
Jul 201713714
Aug 2017191112
Sep 2017111319
Oct 201722618
Nov 201721618
Dec 2017181331
Jan 2018301034
Feb 201815827
Mar 2018211531
Apr 201828815
May 201816627
Jun 2018765
Jul 20181289
Aug 20181066
Sep 2018121111
Oct 20187155
Nov 20188811
Dec 20182823
Jan 2019886
Feb 201917237
Mar 20196109
Apr 20198118
May 20197712
Jun 2019121211
Jul 201931613
Aug 2019101323
Sep 201991314
Oct 2019101110
Nov 20198811
Dec 201922711
Jan 2020879
Feb 202071012
Mar 20209117
Apr 202016411
May 2020989
Jun 20209916
Jul 20201288
Aug 2020998
Sep 2020172018
Oct 202012727
Nov 202014512
Dec 202061314
Jan 202123020
Feb 202151718
Mar 202131310
Apr 202142317
May 202122322
Jun 202151915
Jul 202152214
Aug 2021477
Sep 202141423
Oct 202111024
Nov 202122424
Dec 202141613
Jan 202231511
Feb 202271310
Mar 202212712
Apr 202251513
May 202232117
Jun 202232213
Jul 20220238
Aug 20224188
Sep 202232614
Oct 202262310
Nov 20224156
Dec 20223113
Jan 20233266
Feb 20230119
Mar 202332014
Apr 202301610
May 20230103
Jun 20230131
Jul 202361511
Aug 20237146
Sep 2023087
Oct 202361211
Nov 202311510
Dec 202333310
Jan 202442311
Feb 20241116
Mar 20241629
Apr 202414115
May 202452910
Jun 20245248
Jul 202445823
Aug 202435710
Sep 202442722
Oct 202472513
Nov 202451612
Dec 20247207
Jan 202532815
Feb 20252669
Mar 202533125
Apr 202544029
PreviousNext
Back to top

In this issue

Journal of Nuclear Medicine: 53 (3)
Journal of Nuclear Medicine
Vol. 53, Issue 3
March 1, 2012
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on Journal of Nuclear Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
5-(2-18F-Fluoroethoxy)-l-Tryptophan as a Substrate of System L Transport for Tumor Imaging by PET
(Your Name) has sent you a message from Journal of Nuclear Medicine
(Your Name) thought you would like to see the Journal of Nuclear Medicine web site.
Citation Tools
5-(2-18F-Fluoroethoxy)-l-Tryptophan as a Substrate of System L Transport for Tumor Imaging by PET
Stefanie D. Krämer, Linjing Mu, Adrienne Müller, Claudia Keller, Olga F. Kuznetsova, Christian Schweinsberg, Dominic Franck, Cristina Müller, Tobias L. Ross, Roger Schibli, Simon M. Ametamey
Journal of Nuclear Medicine Mar 2012, 53 (3) 434-442; DOI: 10.2967/jnumed.111.096289

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
5-(2-18F-Fluoroethoxy)-l-Tryptophan as a Substrate of System L Transport for Tumor Imaging by PET
Stefanie D. Krämer, Linjing Mu, Adrienne Müller, Claudia Keller, Olga F. Kuznetsova, Christian Schweinsberg, Dominic Franck, Cristina Müller, Tobias L. Ross, Roger Schibli, Simon M. Ametamey
Journal of Nuclear Medicine Mar 2012, 53 (3) 434-442; DOI: 10.2967/jnumed.111.096289
Twitter logo Facebook logo LinkedIn logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • CONCLUSION
    • DISCLOSURE STATEMENT
    • Acknowledgments
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • PDF

Related Articles

  • This Month in JNM
  • PubMed
  • Google Scholar

Cited By...

  • Assessment of Tryptophan Uptake and Kinetics Using 1-(2-18F-Fluoroethyl)-L-Tryptophan and {alpha}-11C-Methyl-L-Tryptophan PET Imaging in Mice Implanted with Patient-Derived Brain Tumor Xenografts
  • Epileptic Activity Increases Cerebral Amino Acid Transport Assessed by 18F-Fluoroethyl-L-Tyrosine Amino Acid PET: A Potential Brain Tumor Mimic
  • 18F-Fluorodihydroxyphenylalanine PET/CT in Patients with Neuroendocrine Tumors of Unknown Origin: Relation to Tumor Origin and Differentiation
  • Google Scholar

More in this TOC Section

  • 11C-Methionine PET of Myocardial Inflammation in a Rat Model of Experimental Autoimmune Myocarditis
  • Counting Rate Characteristics and Image Distortion in Preclinical PET Imaging During Radiopharmaceutical Therapy
  • Design and Fabrication of Kidney Phantoms for Internal Radiation Dosimetry Using 3D Printing Technology
Show more Basic Science Investigations

Similar Articles

SNMMI

© 2025 SNMMI

Powered by HighWire