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Research ArticleBasic Science Investigation

PET of (R)-11C-Rolipram Binding to Phosphodiesterase-4 Is Reproducible and Sensitive to Increased Norepinephrine in the Rat Heart

Adam J. Thomas, Jean N. DaSilva, Mireille Lortie, Jennifer M. Renaud, Miran Kenk, Rob S. Beanlands and Robert A. deKemp
Journal of Nuclear Medicine February 2011, 52 (2) 263-269; DOI: https://doi.org/10.2967/jnumed.110.082701
Adam J. Thomas
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Jean N. DaSilva
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Mireille Lortie
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Jennifer M. Renaud
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Miran Kenk
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Rob S. Beanlands
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Robert A. deKemp
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Article Information

vol. 52 no. 2 263-269
DOI 
https://doi.org/10.2967/jnumed.110.082701
PubMed 
21270457

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication August 26, 2010
  • Accepted for publication November 3, 2010
  • Published online January 26, 2011.

Copyright & Usage 
© 2011 by Society of Nuclear Medicine

Author Information

  1. Adam J. Thomas1,2,
  2. Jean N. DaSilva1,2,
  3. Mireille Lortie1,
  4. Jennifer M. Renaud1,
  5. Miran Kenk1,2,
  6. Rob S. Beanlands1,2 and
  7. Robert A. deKemp1
  1. 1Cardiovascular PET Molecular Function and Imaging Program, National Cardiac PET Centre, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; and
  2. 2Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
  1. For correspondence or reprints contact: Robert A. deKemp, National Cardiac PET Centre, University of Ottawa Heart Institute, 40 Ruskin St., Ottawa, Ontario, Canada, K1Y 4W7. E-mail: RAdeKemp{at}ottawaheart.ca
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Journal of Nuclear Medicine: 52 (2)
Journal of Nuclear Medicine
Vol. 52, Issue 2
February 1, 2011
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PET of (R)-11C-Rolipram Binding to Phosphodiesterase-4 Is Reproducible and Sensitive to Increased Norepinephrine in the Rat Heart
Adam J. Thomas, Jean N. DaSilva, Mireille Lortie, Jennifer M. Renaud, Miran Kenk, Rob S. Beanlands, Robert A. deKemp
Journal of Nuclear Medicine Feb 2011, 52 (2) 263-269; DOI: 10.2967/jnumed.110.082701

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PET of (R)-11C-Rolipram Binding to Phosphodiesterase-4 Is Reproducible and Sensitive to Increased Norepinephrine in the Rat Heart
Adam J. Thomas, Jean N. DaSilva, Mireille Lortie, Jennifer M. Renaud, Miran Kenk, Rob S. Beanlands, Robert A. deKemp
Journal of Nuclear Medicine Feb 2011, 52 (2) 263-269; DOI: 10.2967/jnumed.110.082701
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  • Characterization of 18F-FPyKYNE-Losartan for Imaging AT1 Receptors
  • Repeatable Noninvasive Measurement of Mouse Myocardial Glucose Uptake with 18F-FDG: Evaluation of Tracer Kinetics in a Type 1 Diabetes Model
  • First Clinical Experience with Integrated Whole-Body PET/MR: Comparison to PET/CT in Patients with Oncologic Diagnoses
  • Google Scholar

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