Skip to main content

Main menu

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
    • Continuing Education
    • JNM Podcasts
  • Subscriptions
    • Subscribers
    • Institutional and Non-member
    • Rates
    • Journal Claims
    • Corporate & Special Sales
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI

User menu

  • Subscribe
  • My alerts
  • Log in
  • Log out
  • My Cart

Search

  • Advanced search
Journal of Nuclear Medicine
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI
  • Subscribe
  • My alerts
  • Log in
  • Log out
  • My Cart
Journal of Nuclear Medicine

Advanced Search

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
    • Continuing Education
    • JNM Podcasts
  • Subscriptions
    • Subscribers
    • Institutional and Non-member
    • Rates
    • Journal Claims
    • Corporate & Special Sales
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • View or Listen to JNM Podcast
  • Visit JNM on Facebook
  • Join JNM on LinkedIn
  • Follow JNM on Twitter
  • Subscribe to our RSS feeds
Meeting ReportInstrumentation and Data Analysis: Image Generation

Optimization of 15O-water activation studies in PET/CT

Richard Laforest, Michael Harrod and Mark Mintun
Journal of Nuclear Medicine May 2009, 50 (supplement 2) 1463;
Richard Laforest
1Washington University, School of Medicine, Mallinckrodt Institute of Radiology, St.Louis, MO
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael Harrod
1Washington University, School of Medicine, Mallinckrodt Institute of Radiology, St.Louis, MO
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mark Mintun
1Washington University, School of Medicine, Mallinckrodt Institute of Radiology, St.Louis, MO
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
Loading

Abstract

1463

Objectives This work aims at reducing the noise in 15O-water brain PET activation studies performed in a modern PET/CT camera operated in 3D. Optimization of imaging conditions requires maximizing the administered activity while maintaining acceptable camera dead time. Typically, in such studies, the NeuroshieldTM is employed to limit the detection of radioactivity outside the PET FOV.

Methods This shield was designed for PET cameras with smaller patient port (56 cm vs 70 cm for Biograph) and does not offer shielding to the detector blocks located in the upper portion of the PET scanner. We have thus modified the NeuroshieldTM by the addition of an additional piece of lead covering the upper portion of the shield and evaluated the imaging performance in terms of counting rate ability and NEC measurements.

Results With the standard NeuroshieldTM, we observe that an injection of 17 mCi yields an average singles counts rate of ~120kcps, while detector blocks located in the upper portion of the detector rings reach singles counting rate exceeding 400 kcps. With the modified neuroshield, we have shown that block counting rate can be maintained around 120 kcps which effectively allows to double the amount of activity that can be injected in the patient while maintaining singles counting rate within acceptable limits (<300 kcps). A point source phantom experiment confirmed this measurement and further indicated that the NeuroShield offers protection for activity located between 6 and 30 cm away from the PET FOV.

Conclusions The proposed modification to the Neuroshield allows to double the injected activity in 15O-water PET brain activation studies which contributes at reducing the noise.

  • © 2009 by Society of Nuclear Medicine
Back to top

In this issue

Journal of Nuclear Medicine
Vol. 50, Issue supplement 2
May 2009
  • Table of Contents
  • Index by author
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on Journal of Nuclear Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Optimization of 15O-water activation studies in PET/CT
(Your Name) has sent you a message from Journal of Nuclear Medicine
(Your Name) thought you would like to see the Journal of Nuclear Medicine web site.
Citation Tools
Optimization of 15O-water activation studies in PET/CT
Richard Laforest, Michael Harrod, Mark Mintun
Journal of Nuclear Medicine May 2009, 50 (supplement 2) 1463;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Optimization of 15O-water activation studies in PET/CT
Richard Laforest, Michael Harrod, Mark Mintun
Journal of Nuclear Medicine May 2009, 50 (supplement 2) 1463;
Twitter logo Facebook logo LinkedIn logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
  • Info & Metrics

Related Articles

  • No related articles found.
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

Instrumentation and Data Analysis: Image Generation

  • Evaluation of collimator blurring, attenuation, and scatter corrections for brain SPECT
  • Improved thallium-201 image contrast with a novel CZT cardiac SPECT system
  • New utility for registration of the CT and PET data in PET/CT
Show more Instrumentation and Data Analysis: Image Generation

Image Generation Posters

  • Evaluation of collimator blurring, attenuation, and scatter corrections for brain SPECT
  • Improved thallium-201 image contrast with a novel CZT cardiac SPECT system
  • New utility for registration of the CT and PET data in PET/CT
Show more Image Generation Posters

Similar Articles

SNMMI

© 2025 SNMMI

Powered by HighWire