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OtherBASIC SCIENCE INVESTIGATIONS

Metabotropic Glutamate Subtype 5 Receptors Are Quantified in the Human Brain with a Novel Radioligand for PET

Amira K. Brown, Yasuyuki Kimura, Sami S. Zoghbi, Fabrice G. Siméon, Jeih-San Liow, William C. Kreisl, Andrew Taku, Masahiro Fujita, Victor W. Pike and Robert B. Innis
Journal of Nuclear Medicine December 2008, 49 (12) 2042-2048; DOI: https://doi.org/10.2967/jnumed.108.056291
Amira K. Brown
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Yasuyuki Kimura
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Sami S. Zoghbi
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Fabrice G. Siméon
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Jeih-San Liow
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William C. Kreisl
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Andrew Taku
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Masahiro Fujita
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Victor W. Pike
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Robert B. Innis
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Article Information

vol. 49 no. 12 2042-2048
DOI 
https://doi.org/10.2967/jnumed.108.056291
PubMed 
19038998

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication July 24, 2008
  • Accepted for publication August 18, 2008
  • Published online November 27, 2008.

Copyright & Usage 
© 2008 by Society of Nuclear Medicine

Author Information

  1. Amira K. Brown,
  2. Yasuyuki Kimura,
  3. Sami S. Zoghbi,
  4. Fabrice G. Siméon,
  5. Jeih-San Liow,
  6. William C. Kreisl,
  7. Andrew Taku,
  8. Masahiro Fujita,
  9. Victor W. Pike and
  10. Robert B. Innis
  1. Molecular Imaging Branch, National Institute of Mental Health, Bethesda, Maryland
  1. For correspondence or reprints contact: Robert B. Innis, Molecular Imaging Branch, National Institute of Mental Health, 31 Center Dr., Room B2/B37 Bethesda, MD 20892-2035. E-mail: robert.innis{at}nih.gov
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Journal of Nuclear Medicine: 49 (12)
Journal of Nuclear Medicine
Vol. 49, Issue 12
December 2008
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Metabotropic Glutamate Subtype 5 Receptors Are Quantified in the Human Brain with a Novel Radioligand for PET
Amira K. Brown, Yasuyuki Kimura, Sami S. Zoghbi, Fabrice G. Siméon, Jeih-San Liow, William C. Kreisl, Andrew Taku, Masahiro Fujita, Victor W. Pike, Robert B. Innis
Journal of Nuclear Medicine Dec 2008, 49 (12) 2042-2048; DOI: 10.2967/jnumed.108.056291

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Metabotropic Glutamate Subtype 5 Receptors Are Quantified in the Human Brain with a Novel Radioligand for PET
Amira K. Brown, Yasuyuki Kimura, Sami S. Zoghbi, Fabrice G. Siméon, Jeih-San Liow, William C. Kreisl, Andrew Taku, Masahiro Fujita, Victor W. Pike, Robert B. Innis
Journal of Nuclear Medicine Dec 2008, 49 (12) 2042-2048; DOI: 10.2967/jnumed.108.056291
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  • 18F-FPEB, a PET Radiopharmaceutical for Quantifying Metabotropic Glutamate 5 Receptors: A First-in-Human Study of Radiochemical Safety, Biokinetics, and Radiation Dosimetry
  • Allosteric Modulation of Family C G-Protein-Coupled Receptors: from Molecular Insights to Therapeutic Perspectives
  • Radiodefluorination of 3-Fluoro-5-(2-(2-[18F](fluoromethyl)-thiazol-4-yl)ethynyl)benzonitrile ([18F]SP203), a Radioligand for Imaging Brain Metabotropic Glutamate Subtype-5 Receptors with Positron Emission Tomography, Occurs by Glutathionylation in Rat Brain
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