Article Figures & Data
Figures
- FIGURE 1.
(A) Graphic presentation of SUVmax means in different combinations of ER and PR states shows no interaction between ER and PR states, indicating that effects of ER and PR states on 18F-FDG uptake were independent of each other. (B) Graphic presentation of SUVmax means in different combinations of ER and C-erbB-2R states shows that for lesions in which both these receptors are either positive or negative, SUVmax is higher than for lesions in which only one is positive. (C) Graphic presentation of SUVmax means in different combinations of C-erbB-2R and PR states shows that for lesions in which both these receptors are either positive or negative, SUVmax is higher than for lesions in which only one is positive.
- FIGURE 2.
18F-FDG PET images of 2 newly diagnosed breast cancer patients who underwent preoperative PET studies. (A) Image for which measured SUVmax of right breast lesion was 2.1 (arrow). After mastectomy, surgical pathology confirmed 1.2-cm invasive ductal cancer. Tissue receptor analysis revealed that this lesion was ER+, PR+, and C-erbB-2R−. (B) Image for which measured SUVmax of left breast lesion was 9.0 (arrow). After mastectomy, surgical pathology confirmed 2-cm invasive ductal cancer that was negative for ER, PR, and C-erbB-2R. ER+ lesion showed significantly lower SUVmax than did ER− lesion.
Tables
ER Negative Positive PR n SUVmax SE n SUVmax SE Negative 33 5.54 0.82 9 2.49 0.52 Positive 3 6.80 0.70 73 3.10 0.28 Source Sum of squares df Mean square F P ER 93.408 1 93.408 9.126 0.003 PR 7.141 1 7.141 0.698 0.405 ER × PR 0.875 1 0.875 0.085 0.771 Error 1,166.876 114 10.236 Corrected total 1,345.293 117 ER Negative Positive C-erbB-2R n SUVmax SE n SUVmax SE Negative 23 6.63 1.10 73 2.77 0.23 Positive 13 3.90 0.62 7 6.01 1.60 Source Sum of squares df Mean square F P ER 10.934 1 10.934 1.175 0.281 C-erbB-2R 0.900 1 0.900 0.097 0.756 ER × C-erbB-2R 129.299 1 129.299 13.895 0.000 Error 1,042.215 112 9.305 Corrected total 1,338.120 115 PR Negative Positive C-erbB-2R n SUVmax SE n SUVmax SE Negative 31 5.47 0.87 65 2.85 0.25 Positive 11 3.23 0.52 9 6.34 1.24 Source Sum of squares df Mean square F P PR 0.959 1 0.959 0.095 0.759 C-erbB-2R 6.334 1 6.334 0.627 0.430 PR × C-erbB-2R 131.359 1 131.359 12.999 0.000 Error 1,131.834 112 10.106 Corrected total 1,338.120 115
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