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Journal of Nuclear Medicine

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OtherBasic Science Investigations

Validation of Gated Blood-Pool SPECT Cardiac Measurements Tested Using a Biventricular Dynamic Physical Phantom

Pieter De Bondt, Kenneth Nichols, Stijn Vandenberghe, Patrick Segers, Olivier De Winter, Christophe Van de Wiele, Pascal Verdonck, Arsalan Shazad, Abu H. Shoyeb and Johan De Sutter
Journal of Nuclear Medicine June 2003, 44 (6) 967-972;
Pieter De Bondt
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Kenneth Nichols
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Stijn Vandenberghe
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Patrick Segers
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Olivier De Winter
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Christophe Van de Wiele
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Pascal Verdonck
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Arsalan Shazad
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Abu H. Shoyeb
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Johan De Sutter
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  • FIGURE 1.
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    FIGURE 1.

    Development and description of phantom. (A) Ventricles were cut off at atrioventricular border. (B) Single-walled RV was attached to double-walled LV. (C) Horizontal long-axis slice (top left), short-axis slice (top right), and vertical long-axis slice (bottom) of activity distribution in phantom. (D) Detail of biventricular model. Valves 1 are used to fill septal wall with gel; valves 2 are used to deaerate tubings, to inject tracer, and to empty ventricles for volume measurements. Valves 3 are in- and outgoing tubes to ventricles. (E) Overview of experimental model, with piston pump in back, membranes in middle, and ventricular model at front.

  • FIGURE 2.
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    FIGURE 2.

    Linear regression and Bland-Altman analysis of mean calculated left and right ventricular volumes (MLVV and MRVV) vs. real left and right ventricular volumes (RLVV and RRVV).

  • FIGURE 3.
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    FIGURE 3.

    Linear regression and Bland-Altman analysis of mean calculated LVEF and RVEF (MLVEF and MRVEF) vs. real LVEF and RVEF (RLVEF and RRVEF).

  • FIGURE 4.
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    FIGURE 4.

    Interobserver variability shown by linear regression of LVEF and RVEF and volume measurements of 2 different observers.

  • FIGURE 5.
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    FIGURE 5.

    Intraobserver variability shown by linear regression of LVEF and RVEF and volume measurements of 2 observations for same observer.

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Journal of Nuclear Medicine
Vol. 44, Issue 6
June 1, 2003
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Validation of Gated Blood-Pool SPECT Cardiac Measurements Tested Using a Biventricular Dynamic Physical Phantom
Pieter De Bondt, Kenneth Nichols, Stijn Vandenberghe, Patrick Segers, Olivier De Winter, Christophe Van de Wiele, Pascal Verdonck, Arsalan Shazad, Abu H. Shoyeb, Johan De Sutter
Journal of Nuclear Medicine Jun 2003, 44 (6) 967-972;

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Validation of Gated Blood-Pool SPECT Cardiac Measurements Tested Using a Biventricular Dynamic Physical Phantom
Pieter De Bondt, Kenneth Nichols, Stijn Vandenberghe, Patrick Segers, Olivier De Winter, Christophe Van de Wiele, Pascal Verdonck, Arsalan Shazad, Abu H. Shoyeb, Johan De Sutter
Journal of Nuclear Medicine Jun 2003, 44 (6) 967-972;
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  • Diagnosis of Diffuse and Localized Arrhythmogenic Right Ventricular Dysplasia by Gated Blood-Pool SPECT
  • Accuracy of 4 Different Algorithms for the Analysis of Tomographic Radionuclide Ventriculography Using a Physical, Dynamic 4-Chamber Cardiac Phantom
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