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Journal of Nuclear Medicine

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OtherClinical Investigations

Detection of Neuroendocrine Tumors: 99mTc-P829 Scintigraphy Compared with 111In-Pentetreotide Scintigraphy

Rachida Lebtahi, Joseph Le Cloirec, Claire Houzard, Doumit Daou, Iradj Sobhani, Geneviève Sassolas, Michel Mignon, Patrick Bourguet and Dominique Le Guludec
Journal of Nuclear Medicine July 2002, 43 (7) 889-895;
Rachida Lebtahi
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Joseph Le Cloirec
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Claire Houzard
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Doumit Daou
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Iradj Sobhani
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Geneviève Sassolas
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Michel Mignon
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Patrick Bourguet
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Dominique Le Guludec
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  • FIGURE 1.
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    FIGURE 1.

    Patient with nonfunctioning endocrine tumor. 111In-pentetreotide scintigraphy shows celiac tumors with liver metastases.

  • FIGURE 2.
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    FIGURE 2.

    Same patient as in Figure 1. Celiac tumoral and liver metastases are not shown by 99mTc-P829 scintigraphy.

  • FIGURE 3.
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    FIGURE 3.

    Patient with Zollinger-Ellison syndrome. 111In-pentetreotide scintigraphy shows multiple celiac tumors with liver and lung metastases.

  • FIGURE 4.
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    FIGURE 4.

    Same patient as in Figure 3. 99mTc-P829 scintigraphy shows lung metastases (smaller than those shown by 111In-pentetreotide scintigraphy). Celiac tumors are not detected. Liver metastases are not clearly seen.

Tables

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    TABLE 1

    Number of Tumor Sites Revealed by 111In-Pentetreotide and 99mTc-P829

    Tumor site111In-Pentetreotide99mTc-P829
    Head and neck65
    Lung and mediastinum1011
    Liver12934
    Celiac area: upper abdomen4123
    Lower abdomen72
    Bone102
    Total20377
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Journal of Nuclear Medicine
Vol. 43, Issue 7
July 1, 2002
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Detection of Neuroendocrine Tumors: 99mTc-P829 Scintigraphy Compared with 111In-Pentetreotide Scintigraphy
Rachida Lebtahi, Joseph Le Cloirec, Claire Houzard, Doumit Daou, Iradj Sobhani, Geneviève Sassolas, Michel Mignon, Patrick Bourguet, Dominique Le Guludec
Journal of Nuclear Medicine Jul 2002, 43 (7) 889-895;

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Detection of Neuroendocrine Tumors: 99mTc-P829 Scintigraphy Compared with 111In-Pentetreotide Scintigraphy
Rachida Lebtahi, Joseph Le Cloirec, Claire Houzard, Doumit Daou, Iradj Sobhani, Geneviève Sassolas, Michel Mignon, Patrick Bourguet, Dominique Le Guludec
Journal of Nuclear Medicine Jul 2002, 43 (7) 889-895;
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  • Radiopeptide Imaging and Therapy in Europe
  • Nuclear medicine techniques for the imaging and treatment of neuroendocrine tumours
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  • Clinical and imaging follow-up after exhaustive liver resection of endocrine metastases: a 15-year monocentric experience
  • Evaluation of [99mTc/EDDA/HYNIC0]Octreotide Derivatives Compared with [111In-DOTA0,Tyr3, Thr8]Octreotide and [111In-DTPA0]Octreotide: Does Tumor or Pancreas Uptake Correlate with the Rate of Internalization?
  • Preclinical Evaluation of New and Highly Potent Analogues of Octreotide for Predictive Imaging and Targeted Radiotherapy
  • Receptor Imaging in Oncology by Means of Nuclear Medicine: Current Status
  • An Intrapatient Comparison of 99mTc-EDDA/HYNIC-TOC with 111In-DTPA-Octreotide for Diagnosis of Somatostatin Receptor-Expressing Tumors
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