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OtherClinical Investigations

The Impact of PET on the Management of Lung Cancer: The Referring Physician’s Perspective

Marc A. Seltzer, Cecelia S. Yap, Daniel H. Silverman, Joubin Meta, Christiaan Schiepers, Michael E. Phelps, Sanjiv S. Gambhir, Jyotsna Rao, Peter E. Valk and Johannes Czernin
Journal of Nuclear Medicine June 2002, 43 (6) 752-756;
Marc A. Seltzer
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Cecelia S. Yap
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Daniel H. Silverman
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Joubin Meta
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Christiaan Schiepers
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Michael E. Phelps
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Sanjiv S. Gambhir
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Jyotsna Rao
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Peter E. Valk
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Johannes Czernin
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    TABLE 1

    Specialty of Referring Physicians

    SpecialtyPercentage
    All referrals (n = 744)Respondents (n = 274)Nonrespondents (n = 470)
    Medical oncology333930
    Surgery303030
    General practice191520
    Pulmonary medicine13916
    Radiation oncology453
    Other/not specified121
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    TABLE 2

    Influence of PET on Clinical Stage

    EffectUCLA Medical Center (n = 133)NCPIC (n = 141)PTotal (n = 274)
    Upstaged31 (23)48 (34)0.0779 (29)
    Downstaged17 (13)25 (18)0.3442 (15)
    No change in stage80 (60)59 (42)0.004139 (51)
    Question not answered5 (4)9 (6)0.4814 (5)
    • Probability value indicates difference in distribution of stage changes between referring physicians at the 2 institutions. Values in parentheses are percentages.

    • View popup
    TABLE 3

    Specific Intermodality Management Changes Resulting from PET

    ChangeUCLA Medical Center (n = 133)NCPIC (n = 141)Total (n = 274)
    Intermodality*44 (33.1)64 (45.4)108 (39.4)
     Surgery to medical15 (11.3)13 (9.2)28 (10.2)
     Surgery to radiation3 (2.3)1 (0.7)4 (1.5)
     Surgery to no treatment5 (3.8)10 (7.1)15 (5.5)
     Medical to surgery6 (4.5)8 (5.7)14 (5.1)
     Medical to radiation1 (0.8)4 (2.8)5 (1.8)
     Medical to no treatment2 (1.5)3 (2.1)5 (1.8)
     Radiation to surgery1 (0.8)3 (2.1)4 (1.5)
     Radiation to medical0 (0)3 (2.1)3 (1.1)
     Radiation to no treatment0 (0)2 (1.4)2 (0.7)
     No treatment to surgery2 (1.5)3 (2.1)5 (1.8)
     No treatment to medical5 (3.8)3 (2.1)8 (2.9)
     No treatment to radiation2 (1.5)0 (0)2 (0.7)
     Combination of changes2 (1.5)11 (7.8)13 (4.7)
    Intramodality†16 (12.0)25 (17.7)41 (15.0)
     Change in surgical approach7 (5.3)13 (9.2)20 (7.3)
     Change in medical approach8 (6.0)7 (5.0)15 (5.5)
     Change in radiation approach1 (0.8)5 (3.5)6 (2.2)
    Combination of inter- and intramodality‡1 (0.8)4 (2.8)5 (1.8)
    None§64 (48.1)38 (27.0)102 (37.2)
    Other/not specified8 (6.0)7 (5.0)15 (5.5)
    Question not answered0 (0)3 (2.1)3 (1.1)
    • ↵* P = 0.05 (NS) for distribution between UCLA Medical Center and NCPIC.

    • ↵† P = 0.25 (NS) for distribution between UCLA Medical Center and NCPIC.

    • ↵‡ P = 0.43 (NS) for distribution between UCLA Medical Center and NCPIC.

    • ↵§ P = 0.0005 for distribution between UCLA Medical Center and NCPIC.

    • NS = not statistically significant.

    • Values in parentheses are percentages.

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Journal of Nuclear Medicine: 43 (6)
Journal of Nuclear Medicine
Vol. 43, Issue 6
June 1, 2002
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The Impact of PET on the Management of Lung Cancer: The Referring Physician’s Perspective
Marc A. Seltzer, Cecelia S. Yap, Daniel H. Silverman, Joubin Meta, Christiaan Schiepers, Michael E. Phelps, Sanjiv S. Gambhir, Jyotsna Rao, Peter E. Valk, Johannes Czernin
Journal of Nuclear Medicine Jun 2002, 43 (6) 752-756;

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The Impact of PET on the Management of Lung Cancer: The Referring Physician’s Perspective
Marc A. Seltzer, Cecelia S. Yap, Daniel H. Silverman, Joubin Meta, Christiaan Schiepers, Michael E. Phelps, Sanjiv S. Gambhir, Jyotsna Rao, Peter E. Valk, Johannes Czernin
Journal of Nuclear Medicine Jun 2002, 43 (6) 752-756;
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