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OtherClinical Investigations

SPECT Imaging in Head Injury Interpreted with Statistical Parametric Mapping

Emmanuel A. Stamatakis, J. T. Lindsay Wilson, Donald M. Hadley and David J. Wyper
Journal of Nuclear Medicine April 2002, 43 (4) 476-483;
Emmanuel A. Stamatakis
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J. T. Lindsay Wilson
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Donald M. Hadley
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David J. Wyper
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  • FIGURE 1.
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    FIGURE 1.

    SPECT (midsections) and SPECT SPM images of 33-y-old man after sports injury. He had GCS rating of 15 on admission. Patient was from focal injury group.

  • FIGURE 2.
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    FIGURE 2.

    Total lesion volume (cm3) detected for each of 22 patients with focal injuries.

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    FIGURE 3.

    Total lesion volume (cm3) detected for each of 22 patients with diffuse injuries.

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    FIGURE 4.

    Frequency distribution of blood flow abnormalities in focal patients (n = 22). (A) Acute. (B) Follow-up. Yellow areas signify more frequent blood flow abnormalities and blue areas signify less frequent abnormalities.

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    FIGURE 5.

    Frequency distribution of blood flow abnormalities in diffuse patients (n = 22). (A) Acute. (B) Follow-up. Yellow areas signify more frequent blood flow abnormalities and blue areas signify less frequent abnormalities.

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    TABLE 1

    Mean Lesion Volumes in Patients with Focal, Diffuse, and All Types of Injury at Acute and Follow-Up Stages and Percentage of Total Lesion Changes from Acute to Follow-Up

    Type of injurySPECTMRI
    Mean lesion volume (cm3)Follow-up/acute (%)Mean lesion volume (cm3)Follow-up/acute (%)
    AcuteFollow-upAcuteFollow-up
    Focal (n = 22)56.3130.395453.9318.8235
    Diffuse (n = 22)12.617.59605.680.7613
    All (n = 61)31.4118.375828.349.7835
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    TABLE 2

    Regions of Decreased Blood Flow Identified in Focal Injury Group

    Focal acuteFocal follow-up
    L and R medial frontal gyrusL and R medial frontal gyrus
    L and R middle frontal gyrusL and R middle frontal gyrus
    L and R inferior frontal gyrusL and R superior frontal gyrus
    L and R superior frontal gyrusR inferior frontal gyrus
    L and R frontal precentral gyrusR frontal precentral gyrus
    L and R anterior cingulateL and R anterior cingulate
    L and R cingulate gyrusL and R cingulate gyrus
    R superior temporal gyrusL and R superior temporal gyrus
    R middle temporal gyrusR middle temporal gyrus
    L parietal angular gyrusL parietal supramarginal gyrus
    L inferior parietal lobuleL inferior parietal lobule
    R parietal postcentral gyrusL and R corpus callosum
    R parietal lobe, precuneusL and R caudate
    R inferior occipital gyrus
    R middle occipital gyrus
    L caudate
    R corpus callosum
    L lentiform nucleus, putamen
    • n = 22 patients.

    • View popup
    TABLE 3

    Regions of Decreased Blood Flow Identified in Diffuse Injury Group

    Diffuse acuteDiffuse follow-up
    L and R medial frontal gyrusR superior frontal gyrus
    L and R frontal lobe, precentral gyrusL frontal precentral gyrus
    L and R superior frontal gyrusL medial frontal gyrus
    L inferior frontal gyrusL and R anterior cingulate
    L and R anterior cingulateL superior temporal gyrus
    L and R cingulate gyrusL insula
    L inferior temporal gyrusL inferior parietal lobule
    L middle temporal gyrusL parietal postcentral gyrus
    L superior temporal gyrusR parietal lobe, precuneus
    L insulaR inferior occipital gyrus
    L parietal angular gyrusL and R middle occipital gyrus
    L parietal postcentral gyrusR occipital lobe, cuneus
    R inferior parietal lobuleR caudate
    L occipital lobe, cuneusL and R thalamus
    L and R middle occipital gyrusL and R brain stem, midbrain
    • n = 22 patients.

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Journal of Nuclear Medicine: 43 (4)
Journal of Nuclear Medicine
Vol. 43, Issue 4
April 1, 2002
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SPECT Imaging in Head Injury Interpreted with Statistical Parametric Mapping
Emmanuel A. Stamatakis, J. T. Lindsay Wilson, Donald M. Hadley, David J. Wyper
Journal of Nuclear Medicine Apr 2002, 43 (4) 476-483;

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SPECT Imaging in Head Injury Interpreted with Statistical Parametric Mapping
Emmanuel A. Stamatakis, J. T. Lindsay Wilson, Donald M. Hadley, David J. Wyper
Journal of Nuclear Medicine Apr 2002, 43 (4) 476-483;
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