Article Figures & Data
Figures
- FIGURE 1.
Blood clearance of 131I-rhIL-8 (A), urinary excretion of 131I radioactivity (B), and anterior (top row) and posterior (bottom row) body images over 24-h interval show faint uptake in lungs and prominent accumulation in spleen with discernable activity in small bowel, kidneys, and bladder (C). T1/2 = half-life.
- FIGURE 2.
Focal uptake of 131I-rhIL-8 in acute infection of left foot (A), less intense but focal 131I-rhIL-8 uptake (arrow) in patient with chronic infection in foot (B), 3-h delayed 99mTc-HDP bone scan shows multifocal degenerative changes in ankles and feet in patient with chronic infection (arrow) of right foot (C) and corresponding 131I-rhIL-8 images depict infection (arrow) but do not image extensive degenerative arthritis (D).
Tables
Age (y) Clinical findings Sedimentation rate (mm/h) Culture 66 Osteomyelitis, right fifth distal phalanx 109 Mixed* 69 Osteomyelitis, first metatarsal, right foot 120 MRSA 53 Osteomyelitis, left great toe 119 Mixed 77 Osteomyelitis, proximal phalanx, left second toe 89 MRSA 67 Osteomyelitis, left foot 102 Pseudomonas, staph 50 Treated osteomyelitis, right great toe 31 S. aureus 44 Left ankle fusion 28 Enterococcus, pseudomonas 72 Recurrent osteomyelitis 29 MRSA 43 History of tibial fracture, treated osteomyelitis, right tibia 3 Not done 75 Osteomyelitis, right foot 79 MRSA 39 Puncture wound, right thumb Not done Not done ↵* Multiple pathogens in specimen.
MRSA = methicillin-resistant Staphylococcus aureus.
Age (y) Diagnosis 99mTc TPBS X-ray 131I-rhIL-8 66 Osteomyelitis, right fifth distal phalanx, DM Abnormal uptake in all phases of distal phalanx, fifth digit, right foot Fracture vs. osteomyelitis of distal phalanx of fifth digit, right foot Uptake in distal phalanx of fifth digit, right foot 69 Osteomyelitis, first metatarsal right foot, DM Abnormal uptake in all phases of first tarsometatarsal joint, right foot Osteomyelitis of first metatarsal, right foot Uptake in first metatarsal, right foot 53 Osteomyelitis, left great toe, DM Abnormal uptake in all phases of distal phalanx, left great toe S/P amputation of second and third digits, left foot Uptake in distal phalanx, left great toe 77 Osteomyelitis, proximal phalanx, left second toe, DM Abnormal uptake in all phases of proximal phalanx, left second toe Erosive changes, second and third metatarsophalangeal joints, left foot Uptake in proximal phalanx of second toe, left foot 67 Osteomyelitis, left foot, DM Abnormal uptake in all phases, fifth left tarsometatarsal joint Soft tissue ulceration/erosion, fifth metatarsal, left foot Uptake in fifth digit, metatarsal left foot 50 Treated osteomyelitis, right great toe, DM Uptake in delayed phase, right great toe Soft tissue swelling in distal right foot, no bony changes No rhIL-8 localization 44 Left ankle fusion Abnormal uptake in all phases of distal left fibula Left tibiotalar/tibiocalcaneal ankle fusion Uptake in left ankle 72 Treated osteomyelitis recurrence, DM Not done Destruction and subluxation of second and third metatarsal heads, left foot Faint uptake, third metatarsal region, left foot 43 History of tibial fracture, treated osteomyelitis, right tibia Abnormal uptake in flow/blood pool, only distal right tibia Previous fracture, right tibia No rhIL-8 localization 75 Osteomyelitis, right foot, DM Abnormal uptake in all phases, fifth metatarsal, right foot Possible erosion fifth metatarsal, right foot Uptake in fifth metatarsal, right foot 39 Puncture wound, right thumb Diffuse uptake in flow/blood pool phases, right thumb Soft tissue swelling, right thumb Diffuse uptake, right thumb DM = diabetes mellitus; S/P = status post; TPBS = triple-phase bone scan.
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