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Research ArticleClinical Investigation

CD70-Targeted [18F]RCCB6 Immuno-PET/CT Imaging in Patients with Nasopharyngeal Carcinoma: A Proof-of-Concept Study

Binyu Shi, You Zhang, Shuo Wu, Dongsheng Xu, Qianyun Wu, Wenzhi Jia, Shuxian An, Cheng Wang, Yongrui Bai, Jianjun Liu, Junjun Zhou and Weijun Wei
Journal of Nuclear Medicine April 2025, jnumed.125.269585; DOI: https://doi.org/10.2967/jnumed.125.269585
Binyu Shi
1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; and
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You Zhang
1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; and
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Shuo Wu
1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; and
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Dongsheng Xu
1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; and
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Qianyun Wu
1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; and
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Wenzhi Jia
1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; and
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Shuxian An
1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; and
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Cheng Wang
1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; and
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Yongrui Bai
2Department of Radiation Oncology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Jianjun Liu
1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; and
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Junjun Zhou
2Department of Radiation Oncology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Weijun Wei
1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; and
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Journal of Nuclear Medicine: 66 (6)
Journal of Nuclear Medicine
Vol. 66, Issue 6
June 1, 2025
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CD70-Targeted [18F]RCCB6 Immuno-PET/CT Imaging in Patients with Nasopharyngeal Carcinoma: A Proof-of-Concept Study
Binyu Shi, You Zhang, Shuo Wu, Dongsheng Xu, Qianyun Wu, Wenzhi Jia, Shuxian An, Cheng Wang, Yongrui Bai, Jianjun Liu, Junjun Zhou, Weijun Wei
Journal of Nuclear Medicine Apr 2025, jnumed.125.269585; DOI: 10.2967/jnumed.125.269585

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CD70-Targeted [18F]RCCB6 Immuno-PET/CT Imaging in Patients with Nasopharyngeal Carcinoma: A Proof-of-Concept Study
Binyu Shi, You Zhang, Shuo Wu, Dongsheng Xu, Qianyun Wu, Wenzhi Jia, Shuxian An, Cheng Wang, Yongrui Bai, Jianjun Liu, Junjun Zhou, Weijun Wei
Journal of Nuclear Medicine Apr 2025, jnumed.125.269585; DOI: 10.2967/jnumed.125.269585
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  • SNMMI Procedure Standard/EANM Practice Guideline for Brain [18F]FDG PET Imaging, Version 2.0
  • Meeting Upcoming Clinical and Diagnostic Needs in Oncologic Imaging: A Structured Reporting System for Fibroblast-Activation-Protein–Targeted Imaging—FAP-RADS Version 1.0
  • Imaging Efficacy of [18F]CTT1057 PET for the Detection of PSMA-Positive Tumors Using Histopathology as Standard of Truth: Results from the GuideView Phase 2/3 Prospective Multicenter Study
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Keywords

  • nasopharyngeal carcinoma
  • CD70
  • immuno-PET/CT
  • molecular imaging
  • single-domain antibody
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