Preclinical evaluation of 203/212Pb-labeled low-molecular-weight compounds for targeted radiopharmaceutical therapy of prostate cancer

Sangeeta Ray Banerjee; IL Minn; Vivek Kumar; Anders Josefsson; Ala Lisok; Mary Brummet; Jian Chen; Ana Kiess; Kwamena Baidoo; Cory Brayton; Ronnie C Mease; Martin Brechbiel; George Sgouros; Robert F Hobbs; Martin G. Pomper

doi:10.2967/jnumed.119.229393

OtherBasic Science (Animal or Phantoms)

Preclinical evaluation of ^203/212Pb-labeled low-molecular-weight compounds for targeted radiopharmaceutical therapy of prostate cancer

Sangeeta Ray Banerjee, IL Minn, Vivek Kumar, Anders Josefsson, Ala Lisok, Mary Brummet, Jian Chen, Ana Kiess, Kwamena Baidoo, Cory Brayton, Ronnie C Mease, Martin Brechbiel, George Sgouros, Robert F Hobbs and Martin G. Pomper

Journal of Nuclear Medicine June 2019, jnumed.119.229393; DOI: https://doi.org/10.2967/jnumed.119.229393

Sangeeta Ray Banerjee

1 Jonhs Hopkins University School of Medicine, United States;

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IL Minn

2 Johns Hopkins University, United States;

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Vivek Kumar

2 Johns Hopkins University, United States;

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Anders Josefsson

3 Johns Hopkins University School of Medicine, United States;

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Ala Lisok

2 Johns Hopkins University, United States;

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Mary Brummet

2 Johns Hopkins University, United States;

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Jian Chen

4 John Hopkins University, United States;

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Ana Kiess

5 Johns Hopkins Medical Institute, United States;

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Kwamena Baidoo

6 National Institutes of Health, United States;

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Cory Brayton

5 Johns Hopkins Medical Institute, United States;

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Ronnie C Mease

2 Johns Hopkins University, United States;

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Martin Brechbiel

7 NCI, United States;

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George Sgouros

3 Johns Hopkins University School of Medicine, United States;

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Robert F Hobbs

2 Johns Hopkins University, United States;

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Martin G. Pomper

8 Johns Hopkins Medical Institutions, United States

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Journal of Nuclear Medicine

Vol. 66, Issue 4

April 1, 2025

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Preclinical evaluation of ^203/212Pb-labeled low-molecular-weight compounds for targeted radiopharmaceutical therapy of prostate cancer

Journal of Nuclear Medicine Jun 2019, jnumed.119.229393; DOI: 10.2967/jnumed.119.229393

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Preclinical evaluation of ^203/212Pb-labeled low-molecular-weight compounds for targeted radiopharmaceutical therapy of prostate cancer

Journal of Nuclear Medicine Jun 2019, jnumed.119.229393; DOI: 10.2967/jnumed.119.229393

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Keywords

Animal Imaging
radionuclide therapy
radiopharmaceuticals
SPECT/CT
α-particle radiopharmaceutical therapy
prostate-specific membrane antigen
murine pharmacokinetics
prostate cancer
surrogate imaging

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