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Research ArticleClinical Investigation
Open Access

Imaging Synaptic Density in Aging and Alzheimer Disease with [18F]SynVesT-1

Joseph Giorgio, David N. Soleimani-Meigooni, Mustafa Janabi, Suzanne L. Baker, Xi Chen, Tyler N. Toueg, Robby Weimer, Bastian Zinnhardt, Ari Green, Gil D. Rabinovici and William J. Jagust
Journal of Nuclear Medicine April 2025, 66 (4) 620-625; DOI: https://doi.org/10.2967/jnumed.124.269005
Joseph Giorgio
1Department of Neuroscience, University of California Berkeley, Berkeley, California;
2School of Psychological Sciences, College of Engineering, Science, and the Environment, University of Newcastle, Newcastle, New South Wales, Australia;
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David N. Soleimani-Meigooni
3Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, California;
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Mustafa Janabi
4Lawrence Berkeley National Laboratory, Berkeley, California;
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Suzanne L. Baker
4Lawrence Berkeley National Laboratory, Berkeley, California;
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Xi Chen
1Department of Neuroscience, University of California Berkeley, Berkeley, California;
5Department of Psychology, Stony Brook University, Stony Brook, New York;
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Tyler N. Toueg
1Department of Neuroscience, University of California Berkeley, Berkeley, California;
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Robby Weimer
6Genentech, Inc; and
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Bastian Zinnhardt
7Roche Switzerland, Basel, Switzerland
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Ari Green
3Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, California;
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Gil D. Rabinovici
3Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, California;
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William J. Jagust
1Department of Neuroscience, University of California Berkeley, Berkeley, California;
4Lawrence Berkeley National Laboratory, Berkeley, California;
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Article Information

vol. 66 no. 4 620-625
DOI 
https://doi.org/10.2967/jnumed.124.269005
PubMed 
40049743

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication October 29, 2024
  • Accepted for publication January 29, 2025
  • Published online April 1, 2025.

Article Versions

  • previous version (March 6, 2025 - 08:08).
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Copyright & Usage 
© 2025 by the Society of Nuclear Medicine and Molecular Imaging. Immediate Open Access: Creative Commons Attribution 4.0 International License (CC BY) allows users to share and adapt with attribution, excluding materials credited to previous publications. License: https://creativecommons.org/licenses/by/4.0/. Details: https://jnm.snmjournals.org/page/permissions.

Author Information

  1. Joseph Giorgio*,1,2,
  2. David N. Soleimani-Meigooni*,3,
  3. Mustafa Janabi4,
  4. Suzanne L. Baker4,
  5. Xi Chen1,5,
  6. Tyler N. Toueg1,
  7. Robby Weimer6,
  8. Bastian Zinnhardt7,
  9. Ari Green3,
  10. Gil D. Rabinovici3 and
  11. William J. Jagust1,4
  1. 1Department of Neuroscience, University of California Berkeley, Berkeley, California;
  2. 2School of Psychological Sciences, College of Engineering, Science, and the Environment, University of Newcastle, Newcastle, New South Wales, Australia;
  3. 3Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, California;
  4. 4Lawrence Berkeley National Laboratory, Berkeley, California;
  5. 5Department of Psychology, Stony Brook University, Stony Brook, New York;
  6. 6Genentech, Inc; and
  7. 7Roche Switzerland, Basel, Switzerland
  1. For correspondence or reprints, contact Joseph Giorgio (jgiorgio{at}berkeley.edu).
  1. ↵* Contributed equally to this work.

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Journal of Nuclear Medicine: 66 (4)
Journal of Nuclear Medicine
Vol. 66, Issue 4
April 1, 2025
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Imaging Synaptic Density in Aging and Alzheimer Disease with [18F]SynVesT-1
Joseph Giorgio, David N. Soleimani-Meigooni, Mustafa Janabi, Suzanne L. Baker, Xi Chen, Tyler N. Toueg, Robby Weimer, Bastian Zinnhardt, Ari Green, Gil D. Rabinovici, William J. Jagust
Journal of Nuclear Medicine Apr 2025, 66 (4) 620-625; DOI: 10.2967/jnumed.124.269005

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Imaging Synaptic Density in Aging and Alzheimer Disease with [18F]SynVesT-1
Joseph Giorgio, David N. Soleimani-Meigooni, Mustafa Janabi, Suzanne L. Baker, Xi Chen, Tyler N. Toueg, Robby Weimer, Bastian Zinnhardt, Ari Green, Gil D. Rabinovici, William J. Jagust
Journal of Nuclear Medicine Apr 2025, 66 (4) 620-625; DOI: 10.2967/jnumed.124.269005
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