Preclinical Evaluation of 177Lu-rhPSMA-10.1, a Radiopharmaceutical for Prostate Cancer: Biodistribution and Therapeutic Efficacy

Caroline Foxton; Bradley Waldron; Rikke Veggerby Grønlund; Jaime (Jim) Simón; Bart Cornelissen; Edward O’Neill; Daniel Stevens

doi:10.2967/jnumed.124.268508

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Preclinical Evaluation of ¹⁷⁷Lu-rhPSMA-10.1, a Radiopharmaceutical for Prostate Cancer: Biodistribution and Therapeutic Efficacy

Caroline Foxton, Bradley Waldron, Rikke Veggerby Grønlund, Jaime (Jim) Simón, Bart Cornelissen, Edward O’Neill and Daniel Stevens

Journal of Nuclear Medicine April 2025, 66 (4) 599-604; DOI: https://doi.org/10.2967/jnumed.124.268508

Caroline Foxton

1Blue Earth Diagnostics Ltd., Oxford, United Kingdom;

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Bradley Waldron

2Blue Earth Therapeutics Ltd., Oxford, United Kingdom;

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Rikke Veggerby Grønlund

3Minerva Imaging, Ølstykke, Denmark;

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Jaime (Jim) Simón

4IsoTherapeutics Group LLC, Angleton, Texas; and

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Bart Cornelissen

5Department of Oncology, University of Oxford, Oxford, United Kingdom

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Edward O’Neill

5Department of Oncology, University of Oxford, Oxford, United Kingdom

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Daniel Stevens

2Blue Earth Therapeutics Ltd., Oxford, United Kingdom;

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Journal of Nuclear Medicine

Vol. 66, Issue 4

April 1, 2025

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Preclinical Evaluation of ¹⁷⁷Lu-rhPSMA-10.1, a Radiopharmaceutical for Prostate Cancer: Biodistribution and Therapeutic Efficacy

Caroline Foxton, Bradley Waldron, Rikke Veggerby Grønlund, Jaime (Jim) Simón, Bart Cornelissen, Edward O’Neill, Daniel Stevens

Journal of Nuclear Medicine Apr 2025, 66 (4) 599-604; DOI: 10.2967/jnumed.124.268508

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Preclinical Evaluation of ¹⁷⁷Lu-rhPSMA-10.1, a Radiopharmaceutical for Prostate Cancer: Biodistribution and Therapeutic Efficacy

Caroline Foxton, Bradley Waldron, Rikke Veggerby Grønlund, Jaime (Jim) Simón, Bart Cornelissen, Edward O’Neill, Daniel Stevens

Journal of Nuclear Medicine Apr 2025, 66 (4) 599-604; DOI: 10.2967/jnumed.124.268508

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Keywords

preclinical
prostate cancer
PSMA
radiopharmaceutical
biodistribution

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Preclinical Evaluation of ¹⁷⁷Lu-rhPSMA-10.1, a Radiopharmaceutical for Prostate Cancer: Biodistribution and Therapeutic Efficacy

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