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Research ArticleThe State of the Art
Open Access

Theranostics for Neuroblastoma: Making Molecular Radiotherapy Work Better

Peter J. Gawne, Helen E. Bryant, Steven G. DuBois, Sally L. George, Juliet Gray, Leona Knox, Kyle B. Matchett, Connie Peet, Katherine A. Vallis, Hugh J. Wallace, Simon Wan and Mark N. Gaze
Journal of Nuclear Medicine April 2025, 66 (4) 490-496; DOI: https://doi.org/10.2967/jnumed.124.269121
Peter J. Gawne
1Centre for Cancer Biomarkers and Biotherapeutics, Barts Cancer Institute, Queen Mary, University of London, London, United Kingdom;
2UCL Cancer Institute, University College London, London, United Kingdom;
3School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom;
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Helen E. Bryant
4School of Medicine and Population Health, University of Sheffield, Sheffield, United Kingdom;
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Steven G. DuBois
5Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Harvard Medical School, Boston, Massachusetts;
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Sally L. George
6Division of Clinical Studies, Institute of Cancer Research, London, United Kingdom;
7Children and Young People’s Unit, Royal Marsden Hospital, London, United Kingdom;
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Juliet Gray
8Centre for Cancer Immunology, University of Southampton, Southampton, United Kingdom;
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Leona Knox
9Solving Kids’ Cancer, London, United Kingdom;
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Kyle B. Matchett
10Personalised Medicine Centre and Clinical Translational Research and Innovation Centre, Altnagelvin Area Hospital, School of Medicine, Ulster University, Derry-Londonderry, United Kingdom;
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Connie Peet
11Department of Radiotherapy, University College London Hospitals NHS Foundation Trust, London, United Kingdom;
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Katherine A. Vallis
12Department of Oncology, University of Oxford, Oxford, United Kingdom;
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Hugh J. Wallace
13Paediatric Nuclear Medicine, Royal Hospital for Children, Glasgow, United Kingdom;
14Department of Clinical Physics and Bioengineering, NHS Greater Glasgow and Clyde, Glasgow, United Kingdom;
15University of Glasgow, Glasgow, United Kingdom;
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Simon Wan
16Institute of Nuclear Medicine, University College London Hospitals NHS Foundation Trust/University College London, London, United Kingdom; and
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Mark N. Gaze
17Department of Oncology, University College London Hospitals NHS Foundation Trust, London, United Kingdom
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Article Information

vol. 66 no. 4 490-496
DOI 
https://doi.org/10.2967/jnumed.124.269121
PubMed 
39978816

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication November 9, 2024
  • Accepted for publication January 17, 2025
  • Published online April 1, 2025.

Article Versions

  • previous version (February 20, 2025 - 08:20).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2025 by the Society of Nuclear Medicine and Molecular Imaging. Immediate Open Access: Creative Commons Attribution 4.0 International License (CC BY) allows users to share and adapt with attribution, excluding materials credited to previous publications. License: https://creativecommons.org/licenses/by/4.0/. Details: https://jnm.snmjournals.org/page/permissions.

Author Information

  1. Peter J. Gawne1,2,3,
  2. Helen E. Bryant4,
  3. Steven G. DuBois5,
  4. Sally L. George6,7,
  5. Juliet Gray8,
  6. Leona Knox9,
  7. Kyle B. Matchett10,
  8. Connie Peet11,
  9. Katherine A. Vallis12,
  10. Hugh J. Wallace13,14,15,
  11. Simon Wan16 and
  12. Mark N. Gaze17
  1. 1Centre for Cancer Biomarkers and Biotherapeutics, Barts Cancer Institute, Queen Mary, University of London, London, United Kingdom;
  2. 2UCL Cancer Institute, University College London, London, United Kingdom;
  3. 3School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom;
  4. 4School of Medicine and Population Health, University of Sheffield, Sheffield, United Kingdom;
  5. 5Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Harvard Medical School, Boston, Massachusetts;
  6. 6Division of Clinical Studies, Institute of Cancer Research, London, United Kingdom;
  7. 7Children and Young People’s Unit, Royal Marsden Hospital, London, United Kingdom;
  8. 8Centre for Cancer Immunology, University of Southampton, Southampton, United Kingdom;
  9. 9Solving Kids’ Cancer, London, United Kingdom;
  10. 10Personalised Medicine Centre and Clinical Translational Research and Innovation Centre, Altnagelvin Area Hospital, School of Medicine, Ulster University, Derry-Londonderry, United Kingdom;
  11. 11Department of Radiotherapy, University College London Hospitals NHS Foundation Trust, London, United Kingdom;
  12. 12Department of Oncology, University of Oxford, Oxford, United Kingdom;
  13. 13Paediatric Nuclear Medicine, Royal Hospital for Children, Glasgow, United Kingdom;
  14. 14Department of Clinical Physics and Bioengineering, NHS Greater Glasgow and Clyde, Glasgow, United Kingdom;
  15. 15University of Glasgow, Glasgow, United Kingdom;
  16. 16Institute of Nuclear Medicine, University College London Hospitals NHS Foundation Trust/University College London, London, United Kingdom; and
  17. 17Department of Oncology, University College London Hospitals NHS Foundation Trust, London, United Kingdom
  1. For correspondence or reprints, contact Mark N. Gaze (mgaze@nhs.netmark.gaze{at}ucl.ac.uk).
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Journal of Nuclear Medicine: 66 (4)
Journal of Nuclear Medicine
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April 1, 2025
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Theranostics for Neuroblastoma: Making Molecular Radiotherapy Work Better
Peter J. Gawne, Helen E. Bryant, Steven G. DuBois, Sally L. George, Juliet Gray, Leona Knox, Kyle B. Matchett, Connie Peet, Katherine A. Vallis, Hugh J. Wallace, Simon Wan, Mark N. Gaze
Journal of Nuclear Medicine Apr 2025, 66 (4) 490-496; DOI: 10.2967/jnumed.124.269121

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Theranostics for Neuroblastoma: Making Molecular Radiotherapy Work Better
Peter J. Gawne, Helen E. Bryant, Steven G. DuBois, Sally L. George, Juliet Gray, Leona Knox, Kyle B. Matchett, Connie Peet, Katherine A. Vallis, Hugh J. Wallace, Simon Wan, Mark N. Gaze
Journal of Nuclear Medicine Apr 2025, 66 (4) 490-496; DOI: 10.2967/jnumed.124.269121
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