Single Chelator–Minibody Theranostic Agents for 89Zr PET Imaging and 177Lu Radiopharmaceutical Therapy of PSMA-Expressing Prostate Cancer

Khanh-Van Ho; David S. Tatum; Lisa Watkinson; Terry Carmack; Fang Jia; Alessandro Mascioni; Charles A. Maitz; Darren Magda; Carolyn J. Anderson

doi:10.2967/jnumed.124.267667

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Single Chelator–Minibody Theranostic Agents for ⁸⁹Zr PET Imaging and ¹⁷⁷Lu Radiopharmaceutical Therapy of PSMA-Expressing Prostate Cancer

Khanh-Van Ho, David S. Tatum, Lisa Watkinson, Terry Carmack, Fang Jia, Alessandro Mascioni, Charles A. Maitz, Darren Magda and Carolyn J. Anderson

Journal of Nuclear Medicine September 2024, 65 (9) 1435-1442; DOI: https://doi.org/10.2967/jnumed.124.267667

Khanh-Van Ho

1Department of Chemistry, University of Missouri, Columbia, Missouri;

2Molecular Imaging and Theranostics Center, University of Missouri, Columbia, Missouri;

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David S. Tatum

3Lumiphore Inc., Berkeley, California;

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Lisa Watkinson

2Molecular Imaging and Theranostics Center, University of Missouri, Columbia, Missouri;

4Research Service, Harry S. Truman Memorial Veterans’ Hospital, Columbia, Missouri;

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Terry Carmack

2Molecular Imaging and Theranostics Center, University of Missouri, Columbia, Missouri;

4Research Service, Harry S. Truman Memorial Veterans’ Hospital, Columbia, Missouri;

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Fang Jia

5ImaginAb Inc., Inglewood, California;

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Alessandro Mascioni

5ImaginAb Inc., Inglewood, California;

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Charles A. Maitz

6Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, Missouri;

7MU Research Reactor, University of Missouri, Columbia, Missouri;

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Darren Magda

3Lumiphore Inc., Berkeley, California;

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Carolyn J. Anderson

1Department of Chemistry, University of Missouri, Columbia, Missouri;

2Molecular Imaging and Theranostics Center, University of Missouri, Columbia, Missouri;

8Department of Radiology, University of Missouri, Columbia, Missouri; and

9Ellis Fischel Cancer Center, University of Missouri, Columbia, Missouri

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Journal of Nuclear Medicine

Vol. 65, Issue 9

September 1, 2024

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Single Chelator–Minibody Theranostic Agents for ⁸⁹Zr PET Imaging and ¹⁷⁷Lu Radiopharmaceutical Therapy of PSMA-Expressing Prostate Cancer

Khanh-Van Ho, David S. Tatum, Lisa Watkinson, Terry Carmack, Fang Jia, Alessandro Mascioni, Charles A. Maitz, Darren Magda, Carolyn J. Anderson

Journal of Nuclear Medicine Sep 2024, 65 (9) 1435-1442; DOI: 10.2967/jnumed.124.267667

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Single Chelator–Minibody Theranostic Agents for ⁸⁹Zr PET Imaging and ¹⁷⁷Lu Radiopharmaceutical Therapy of PSMA-Expressing Prostate Cancer

Khanh-Van Ho, David S. Tatum, Lisa Watkinson, Terry Carmack, Fang Jia, Alessandro Mascioni, Charles A. Maitz, Darren Magda, Carolyn J. Anderson

Journal of Nuclear Medicine Sep 2024, 65 (9) 1435-1442; DOI: 10.2967/jnumed.124.267667

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Keywords

L804
minibody
theranostics
targeted radiotherapy
prostate cancer

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Single Chelator–Minibody Theranostic Agents for ⁸⁹Zr PET Imaging and ¹⁷⁷Lu Radiopharmaceutical Therapy of PSMA-Expressing Prostate Cancer

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