Article Figures & Data
Tables
- Table 1.
Baseline Demographics and Clinical Characteristics Before or at Start of 177Lu-PSMA
Characteristic Data Patients 133 Age (y) 73 (49–90) ECOG PS 1 17 (13) 2 49 (37) 3 13 (10) 4 2 (2) Missing 52 (39) PSA* (ng/mL) (n = 130) 286 (1–12,229) ALP* (U/L) (n = 112) 146 (23–973) Extent of metastatic disease† Bone metastases with lymph node metastases 63 (47) Bone metastases without lymph node metastases 33 (25) Visceral metastases 36 (27) Prior therapies for mCRPC, n (%) ≥4 Life-prolonging therapies‡ 76 (57) 223Ra 133 (100) Number of 223Ra injections 1–4 35 (26) 5–6 98 (74) Abiraterone 95 (71) Enzalutamide 92 (69) Abiraterone and enzalutamide 71 (53) Chemotherapy lines§ 0 31 (23) 1 67 (50) ≥2 35 (26) Docetaxel 99 (74) Cyclesǁ 1 − 4 27 (24) ≥5 59 (53) Missing/unknown 26 (23) Cabazitaxel 30 (23) Cycles¶ 1 − 4 cycles 7 (21) ≥5 cycles 14 (42) Missing/unknown 12 (36) ↵* In case of multiple measures, value nearest to 177Lu-PSMA start was chosen.
↵† Prebaseline period, patient may have multiple metastatic diseases.
↵‡ Docetaxel, cabazitaxel, abiraterone, enzalutamide, 223Ra.
↵§ Chemotherapies with same start date ± 15 d were counted as 1 line.
↵ǁ n = 112; percentages were based on number of docetaxel therapies (i.e., patients who received 2 lines of docetaxel were counted twice).
↵¶ n = 33; percentages were based on number of cabazitaxel therapies (i.e., patients who received 2 lines of cabazitaxel were counted twice).
ECOG PS = Eastern Cooperative Oncology Group performance status. Qualitative data are number and percentage; continuous data are median and range.