Research ArticleClinical Investigation
Open Access
First-in-Human Evaluation of Site-Specifically Labeled 89Zr-Pertuzumab in Patients with HER2-Positive Breast Cancer
Randy Yeh, Joseph A. O’Donoghue, Vetri Sudar Jayaprakasam, Audrey Mauguen, Ryan Min, Sue Park, Julia P. Brockway, Jacqueline F. Bromberg, W Iris Zhi, Mark E. Robson, Rachel Sanford, Shanu Modi, Brian J. Agnew, Serge K. Lyashchenko, Jason S. Lewis, Gary A. Ulaner and Brian M. Zeglis
Journal of Nuclear Medicine March 2024, 65 (3) 386-393; DOI: https://doi.org/10.2967/jnumed.123.266392
Randy Yeh
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
2Department of Radiology, Weill Cornell Medical College, New York, New York;
Joseph A. O’Donoghue
3Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York;
Vetri Sudar Jayaprakasam
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
2Department of Radiology, Weill Cornell Medical College, New York, New York;
Audrey Mauguen
4Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, New York;
Ryan Min
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
Sue Park
5Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York;
6Department of Medicine, Weill Cornell Medical College, New York, New York;
Julia P. Brockway
5Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York;
6Department of Medicine, Weill Cornell Medical College, New York, New York;
Jacqueline F. Bromberg
5Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York;
6Department of Medicine, Weill Cornell Medical College, New York, New York;
W Iris Zhi
5Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York;
Mark E. Robson
5Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York;
6Department of Medicine, Weill Cornell Medical College, New York, New York;
Rachel Sanford
5Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York;
6Department of Medicine, Weill Cornell Medical College, New York, New York;
Shanu Modi
5Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York;
6Department of Medicine, Weill Cornell Medical College, New York, New York;
Brian J. Agnew
7Biosciences Division, Thermo Fisher Scientific, Eugene, Oregon;
Serge K. Lyashchenko
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
2Department of Radiology, Weill Cornell Medical College, New York, New York;
Jason S. Lewis
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
2Department of Radiology, Weill Cornell Medical College, New York, New York;
8Program in Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York;
Gary A. Ulaner
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
2Department of Radiology, Weill Cornell Medical College, New York, New York;
9Molecular Imaging and Therapy, Hoag Family Cancer Institute, Newport Beach, California;
10Departments of Radiology and Translational Genomics, University of Southern California, Los Angeles, California; and
Brian M. Zeglis
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
2Department of Radiology, Weill Cornell Medical College, New York, New York;
11Department of Chemistry, Hunter College, New York, New York

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Journal of Nuclear Medicine
Vol. 65, Issue 3
March 1, 2024
First-in-Human Evaluation of Site-Specifically Labeled 89Zr-Pertuzumab in Patients with HER2-Positive Breast Cancer
Randy Yeh, Joseph A. O’Donoghue, Vetri Sudar Jayaprakasam, Audrey Mauguen, Ryan Min, Sue Park, Julia P. Brockway, Jacqueline F. Bromberg, W Iris Zhi, Mark E. Robson, Rachel Sanford, Shanu Modi, Brian J. Agnew, Serge K. Lyashchenko, Jason S. Lewis, Gary A. Ulaner, Brian M. Zeglis
Journal of Nuclear Medicine Mar 2024, 65 (3) 386-393; DOI: 10.2967/jnumed.123.266392
First-in-Human Evaluation of Site-Specifically Labeled 89Zr-Pertuzumab in Patients with HER2-Positive Breast Cancer
Randy Yeh, Joseph A. O’Donoghue, Vetri Sudar Jayaprakasam, Audrey Mauguen, Ryan Min, Sue Park, Julia P. Brockway, Jacqueline F. Bromberg, W Iris Zhi, Mark E. Robson, Rachel Sanford, Shanu Modi, Brian J. Agnew, Serge K. Lyashchenko, Jason S. Lewis, Gary A. Ulaner, Brian M. Zeglis
Journal of Nuclear Medicine Mar 2024, 65 (3) 386-393; DOI: 10.2967/jnumed.123.266392