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Research ArticleFEATURED ARTICLE OF THE MONTH

[68Ga]Ga-RAYZ-8009: A Glypican-3–Targeted Diagnostic Radiopharmaceutical for Hepatocellular Carcinoma Molecular Imaging—A First-in-Human Case Series

Alex J. Poot, Constantin Lapa, Wolfgang A. Weber, Marnix G.E.H. Lam, Matthias Eiber, Alexander Dierks, Ralph A. Bundschuh and Arthur J.A.T. Braat
Journal of Nuclear Medicine October 2024, 65 (10) 1597-1603; DOI: https://doi.org/10.2967/jnumed.124.268147
Alex J. Poot
1Radiology and Nuclear Medicine, UMC Utrecht, Utrecht, The Netherlands;
2Radiology and Nuclear Medicine, Princess Máxima Center, Utrecht, The Netherlands;
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Constantin Lapa
3Nuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany;
4Bavarian Cancer Research Center, Munich, Germany;
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Wolfgang A. Weber
4Bavarian Cancer Research Center, Munich, Germany;
5Department of Nuclear Medicine, School of Medicine and Health, TUM Klinikum, Technical University of Munich, Munich, Germany; and
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Marnix G.E.H. Lam
1Radiology and Nuclear Medicine, UMC Utrecht, Utrecht, The Netherlands;
2Radiology and Nuclear Medicine, Princess Máxima Center, Utrecht, The Netherlands;
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Matthias Eiber
4Bavarian Cancer Research Center, Munich, Germany;
5Department of Nuclear Medicine, School of Medicine and Health, TUM Klinikum, Technical University of Munich, Munich, Germany; and
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Alexander Dierks
3Nuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany;
4Bavarian Cancer Research Center, Munich, Germany;
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Ralph A. Bundschuh
3Nuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany;
4Bavarian Cancer Research Center, Munich, Germany;
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Arthur J.A.T. Braat
1Radiology and Nuclear Medicine, UMC Utrecht, Utrecht, The Netherlands;
2Radiology and Nuclear Medicine, Princess Máxima Center, Utrecht, The Netherlands;
6Netherlands Cancer Institute, Amsterdam, The Netherlands
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Article Information

vol. 65 no. 10 1597-1603
DOI 
https://doi.org/10.2967/jnumed.124.268147
PubMed 
39266293

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication May 28, 2024
  • Accepted for publication July 17, 2024
  • Published online October 1, 2024.

Article Versions

  • previous version (September 12, 2024 - 08:33).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2024 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Alex J. Poot1,2,
  2. Constantin Lapa3,4,
  3. Wolfgang A. Weber4,5,
  4. Marnix G.E.H. Lam1,2,
  5. Matthias Eiber4,5,
  6. Alexander Dierks3,4,
  7. Ralph A. Bundschuh3,4 and
  8. Arthur J.A.T. Braat1,2,6
  1. 1Radiology and Nuclear Medicine, UMC Utrecht, Utrecht, The Netherlands;
  2. 2Radiology and Nuclear Medicine, Princess Máxima Center, Utrecht, The Netherlands;
  3. 3Nuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany;
  4. 4Bavarian Cancer Research Center, Munich, Germany;
  5. 5Department of Nuclear Medicine, School of Medicine and Health, TUM Klinikum, Technical University of Munich, Munich, Germany; and
  6. 6Netherlands Cancer Institute, Amsterdam, The Netherlands
  1. For correspondence or reprints, contact Arthur J.A.T. Braat (a.j.a.t.braat{at}umcutrecht.nl).
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Oct 20246841420472
Nov 2024198558286
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Journal of Nuclear Medicine: 65 (10)
Journal of Nuclear Medicine
Vol. 65, Issue 10
October 1, 2024
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[68Ga]Ga-RAYZ-8009: A Glypican-3–Targeted Diagnostic Radiopharmaceutical for Hepatocellular Carcinoma Molecular Imaging—A First-in-Human Case Series
Alex J. Poot, Constantin Lapa, Wolfgang A. Weber, Marnix G.E.H. Lam, Matthias Eiber, Alexander Dierks, Ralph A. Bundschuh, Arthur J.A.T. Braat
Journal of Nuclear Medicine Oct 2024, 65 (10) 1597-1603; DOI: 10.2967/jnumed.124.268147

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[68Ga]Ga-RAYZ-8009: A Glypican-3–Targeted Diagnostic Radiopharmaceutical for Hepatocellular Carcinoma Molecular Imaging—A First-in-Human Case Series
Alex J. Poot, Constantin Lapa, Wolfgang A. Weber, Marnix G.E.H. Lam, Matthias Eiber, Alexander Dierks, Ralph A. Bundschuh, Arthur J.A.T. Braat
Journal of Nuclear Medicine Oct 2024, 65 (10) 1597-1603; DOI: 10.2967/jnumed.124.268147
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Cited By...

  • [68Ga]Ga-RAYZ-8009: A Peptide PET Tracer for Targeting HCC in Humans
  • Noninvasive Characterization of Hepatic Lesions by Means of Glypican-3-Directed PET/CT
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  • glypican-3
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