Article Figures & Data
Figures
- FIGURE 1.
Axial 18F-FDG PET (A), 18F-FDG PET/T1-weighted gradient echo (LAVA) MRI (B), axial DW MRI (C), and DW MRI/LAVA MRI (D) in 14-y-old girl with bilateral ovarian Sertoli-Leydig tumors. Scans were obtained 3 mo before first COVID-19 vaccination dose (first column) and 2 mo after third vaccination dose (6 mo after first vaccination; second column). After vaccination, 18F-FDG PET and 18F-FDG PET/LAVA MRI showed increased uptake in thymus (pink arrows in A and B) and axillary lymph nodes (blue arrow in A and B); similarly, DW MRI and DW MRI/LAVA MRI showed restricted diffusion in thymus (pink arrows in C and D) and axillary lymph nodes (blue arrows in C and D). DWI = diffusion-weighted imaging; LAVA = liver acquisition with volume acquisition.
- FIGURE 2.
18F-FDG PET/MRI parameters before and after COVID-19 vaccination: SUVmax of thymus and axillary lymph nodes (A and B), LDi × SDi of thymus (C), mean ADC of thymus (D), and mean ADC of lymph nodes (E). Follow-up 18F-FDG PET/MRI scans for patients 1, 2, 3, 4, 5, and 6 were obtained 76, 21, 66, 9, 121, and 6 d after their last vaccination, respectively. SUVmax of thymus (P = 0.02) and axillary lymph nodes (P = 0.03) significantly increased after vaccination, thymic size approximated by LDi × SDi increased (P = 0.13), and mean ADC of thymus (P = 0.08) and axillary lymph nodes (P = 0.07) decreased. Significance was computed using 2-tailed paired t test. LDi = longest transverse diameter; SDi = shortest transverse diameter.
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