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Research ArticleFEATURED BASIC SCIENCE ARTICLE

Preclinical Characterization of the Tau PET Tracer [18F]SNFT-1: Comparison of Tau PET Tracers

Ryuichi Harada, Pradith Lerdsirisuk, Yuki Shimizu, Yuka Yokoyama, Yiqing Du, Kaede Kudo, Michinori Ezura, Yoichi Ishikawa, Ren Iwata, Miho Shidahara, Aiko Ishiki, Akio Kikuchi, Yuya Hatano, Tomohiko Ishihara, Osamu Onodera, Yasushi Iwasaki, Mari Yoshida, Yasuyuki Taki, Hiroyuki Arai, Yukitsuka Kudo, Kazuhiko Yanai, Shozo Furumoto and Nobuyuki Okamura
Journal of Nuclear Medicine September 2023, 64 (9) 1495-1501; DOI: https://doi.org/10.2967/jnumed.123.265593
Ryuichi Harada
1Department of Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan;
2Division of Brain Science, Department of Aging Research and Geriatric Medicine, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan;
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Pradith Lerdsirisuk
3Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan;
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Yuki Shimizu
3Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan;
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Yuka Yokoyama
3Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan;
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Yiqing Du
1Department of Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan;
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Kaede Kudo
2Division of Brain Science, Department of Aging Research and Geriatric Medicine, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan;
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Michinori Ezura
4Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan;
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Yoichi Ishikawa
3Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan;
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Ren Iwata
3Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan;
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Miho Shidahara
5Department of Quantum Science and Energy Engineering, Tohoku University, Sendai, Japan;
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Aiko Ishiki
2Division of Brain Science, Department of Aging Research and Geriatric Medicine, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan;
6Division of Community Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan;
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Akio Kikuchi
4Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan;
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Yuya Hatano
7Department of Neurology, Brain Research Institute, Niigata University, Niigata, Japan;
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Tomohiko Ishihara
7Department of Neurology, Brain Research Institute, Niigata University, Niigata, Japan;
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Osamu Onodera
7Department of Neurology, Brain Research Institute, Niigata University, Niigata, Japan;
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Yasushi Iwasaki
8Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, Nagakute, Japan; and
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Mari Yoshida
8Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, Nagakute, Japan; and
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Yasuyuki Taki
2Division of Brain Science, Department of Aging Research and Geriatric Medicine, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan;
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Hiroyuki Arai
2Division of Brain Science, Department of Aging Research and Geriatric Medicine, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan;
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Yukitsuka Kudo
2Division of Brain Science, Department of Aging Research and Geriatric Medicine, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan;
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Kazuhiko Yanai
3Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan;
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Shozo Furumoto
3Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan;
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Nobuyuki Okamura
2Division of Brain Science, Department of Aging Research and Geriatric Medicine, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan;
9Division of Pharmacology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan
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Article Information

vol. 64 no. 9 1495-1501
DOI 
https://doi.org/10.2967/jnumed.123.265593
PubMed 
37321821

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication February 24, 2023
  • Revision received May 3, 2023
  • Published online September 1, 2023.

Article Versions

  • previous version (June 15, 2023 - 08:30).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2023 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Ryuichi Harada1,2,
  2. Pradith Lerdsirisuk3,
  3. Yuki Shimizu3,
  4. Yuka Yokoyama3,
  5. Yiqing Du1,
  6. Kaede Kudo2,
  7. Michinori Ezura4,
  8. Yoichi Ishikawa3,
  9. Ren Iwata3,
  10. Miho Shidahara5,
  11. Aiko Ishiki2,6,
  12. Akio Kikuchi4,
  13. Yuya Hatano7,
  14. Tomohiko Ishihara7,
  15. Osamu Onodera7,
  16. Yasushi Iwasaki8,
  17. Mari Yoshida8,
  18. Yasuyuki Taki2,
  19. Hiroyuki Arai2,
  20. Yukitsuka Kudo2,
  21. Kazuhiko Yanai3,
  22. Shozo Furumoto3 and
  23. Nobuyuki Okamura2,9
  1. 1Department of Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan;
  2. 2Division of Brain Science, Department of Aging Research and Geriatric Medicine, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan;
  3. 3Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan;
  4. 4Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan;
  5. 5Department of Quantum Science and Energy Engineering, Tohoku University, Sendai, Japan;
  6. 6Division of Community Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan;
  7. 7Department of Neurology, Brain Research Institute, Niigata University, Niigata, Japan;
  8. 8Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, Nagakute, Japan; and
  9. 9Division of Pharmacology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan
  1. For correspondence or reprints, contact Ryuichi Harada (ryuichi.harada.c8{at}tohoku.ac.jp).
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Journal of Nuclear Medicine: 64 (9)
Journal of Nuclear Medicine
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September 1, 2023
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Preclinical Characterization of the Tau PET Tracer [18F]SNFT-1: Comparison of Tau PET Tracers
Ryuichi Harada, Pradith Lerdsirisuk, Yuki Shimizu, Yuka Yokoyama, Yiqing Du, Kaede Kudo, Michinori Ezura, Yoichi Ishikawa, Ren Iwata, Miho Shidahara, Aiko Ishiki, Akio Kikuchi, Yuya Hatano, Tomohiko Ishihara, Osamu Onodera, Yasushi Iwasaki, Mari Yoshida, Yasuyuki Taki, Hiroyuki Arai, Yukitsuka Kudo, Kazuhiko Yanai, Shozo Furumoto, Nobuyuki Okamura
Journal of Nuclear Medicine Sep 2023, 64 (9) 1495-1501; DOI: 10.2967/jnumed.123.265593

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Preclinical Characterization of the Tau PET Tracer [18F]SNFT-1: Comparison of Tau PET Tracers
Ryuichi Harada, Pradith Lerdsirisuk, Yuki Shimizu, Yuka Yokoyama, Yiqing Du, Kaede Kudo, Michinori Ezura, Yoichi Ishikawa, Ren Iwata, Miho Shidahara, Aiko Ishiki, Akio Kikuchi, Yuya Hatano, Tomohiko Ishihara, Osamu Onodera, Yasushi Iwasaki, Mari Yoshida, Yasuyuki Taki, Hiroyuki Arai, Yukitsuka Kudo, Kazuhiko Yanai, Shozo Furumoto, Nobuyuki Okamura
Journal of Nuclear Medicine Sep 2023, 64 (9) 1495-1501; DOI: 10.2967/jnumed.123.265593
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Keywords

  • tau
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