CXCR4-Directed Imaging and Endoradiotherapy in Desmoplastic Small Round Cell Tumors

Ingo Hartlapp; Philipp E. Hartrampf; Sebastian E. Serfling; Vanessa Wild; Alexander Weich; Leo Rasche; Sabine Roth; Andreas Rosenwald; Patrick W. Mihatsch; Anne Hendricks; Armin Wiegering; Verena Wiegering; Heribert Hänscheid; Andreas Schirbel; Rudolf A. Werner; Andreas K. Buck; Hans-Jürgen Wester; Hermann Einsele; Volker Kunzmann; Constantin Lapa; K. Martin Kortüm

doi:10.2967/jnumed.123.265464

Research ArticleClinical Investigation

CXCR4-Directed Imaging and Endoradiotherapy in Desmoplastic Small Round Cell Tumors

Ingo Hartlapp, Philipp E. Hartrampf, Sebastian E. Serfling, Vanessa Wild, Alexander Weich, Leo Rasche, Sabine Roth, Andreas Rosenwald, Patrick W. Mihatsch, Anne Hendricks, Armin Wiegering, Verena Wiegering, Heribert Hänscheid, Andreas Schirbel, Rudolf A. Werner, Andreas K. Buck, Hans-Jürgen Wester, Hermann Einsele, Volker Kunzmann, Constantin Lapa and K. Martin Kortüm

Journal of Nuclear Medicine September 2023, 64 (9) 1424-1430; DOI: https://doi.org/10.2967/jnumed.123.265464

Ingo Hartlapp

1Department of Internal Medicine II, Medical Oncology and Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany;

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Philipp E. Hartrampf

2Department of Nuclear Medicine and Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany;

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Sebastian E. Serfling

2Department of Nuclear Medicine and Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany;

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Vanessa Wild

3Department of Pathology and Comprehensive Cancer Center Mainfranken, University of Würzburg, Würzburg, Germany;

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Alexander Weich

1Department of Internal Medicine II, Medical Oncology and Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany;

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Leo Rasche

1Department of Internal Medicine II, Medical Oncology and Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany;

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Sabine Roth

3Department of Pathology and Comprehensive Cancer Center Mainfranken, University of Würzburg, Würzburg, Germany;

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Andreas Rosenwald

3Department of Pathology and Comprehensive Cancer Center Mainfranken, University of Würzburg, Würzburg, Germany;

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Patrick W. Mihatsch

4Department of Diagnostic and Interventional Radiology and Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany;

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Anne Hendricks

5Department of General, Visceral, Transplantation, Vascular, and Pediatric Surgery and Comprehensive Cancer Center Mainfranken Würzburg, University Hospital Würzburg, Würzburg, Germany;

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Armin Wiegering

5Department of General, Visceral, Transplantation, Vascular, and Pediatric Surgery and Comprehensive Cancer Center Mainfranken Würzburg, University Hospital Würzburg, Würzburg, Germany;

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Verena Wiegering

6Children’s Hospital and Comprehensive Cancer Center Mainfranken, University of Würzburg, Würzburg, Germany;

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Heribert Hänscheid

2Department of Nuclear Medicine and Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany;

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Andreas Schirbel

2Department of Nuclear Medicine and Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany;

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Rudolf A. Werner

2Department of Nuclear Medicine and Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany;

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Andreas K. Buck

2Department of Nuclear Medicine and Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany;

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Hans-Jürgen Wester

7Pharmaceutical Radiochemistry, Technical University Munich, München, Germany; and

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Hermann Einsele

1Department of Internal Medicine II, Medical Oncology and Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany;

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Volker Kunzmann

1Department of Internal Medicine II, Medical Oncology and Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany;

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Constantin Lapa

8Nuclear Medicine, Medical Faculty, University of Augsburg, Augsburg, Germany

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K. Martin Kortüm

1Department of Internal Medicine II, Medical Oncology and Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany;

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September 1, 2023

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CXCR4-Directed Imaging and Endoradiotherapy in Desmoplastic Small Round Cell Tumors

Journal of Nuclear Medicine Sep 2023, 64 (9) 1424-1430; DOI: 10.2967/jnumed.123.265464

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CXCR4-Directed Imaging and Endoradiotherapy in Desmoplastic Small Round Cell Tumors

Journal of Nuclear Medicine Sep 2023, 64 (9) 1424-1430; DOI: 10.2967/jnumed.123.265464

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Keywords

desmoplastic small round cell tumor
CXCR4
endoradiotherapy
theranostics

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