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Research ArticleClinical Investigation
Open Access

Superior Tumor Detection for 68Ga-FAPI-46 Versus 18F-FDG PET/CT and Conventional CT in Patients with Cholangiocarcinoma

Kim M. Pabst, Marija Trajkovic-Arsic, Phyllis F.Y. Cheung, Simone Ballke, Katja Steiger, Timo Bartel, Benedikt M. Schaarschmidt, Aleksandar Milosevic, Robert Seifert, Michael Nader, Lukas Kessler, Jens T. Siveke, Katharina Lueckerath, Stefan Kasper, Ken Herrmann, Nader Hirmas, Hartmut H. Schmidt, Rainer Hamacher and Wolfgang P. Fendler
Journal of Nuclear Medicine July 2023, 64 (7) 1049-1055; DOI: https://doi.org/10.2967/jnumed.122.265215
Kim M. Pabst
1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Essen, Germany;
2German Cancer Consortium, partner site University Hospital Essen, Essen, Germany;
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Marija Trajkovic-Arsic
2German Cancer Consortium, partner site University Hospital Essen, Essen, Germany;
3Division of Solid Tumor Translational Oncology, German Cancer Research Center, Heidelberg, Germany;
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Phyllis F.Y. Cheung
2German Cancer Consortium, partner site University Hospital Essen, Essen, Germany;
3Division of Solid Tumor Translational Oncology, German Cancer Research Center, Heidelberg, Germany;
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Simone Ballke
4Institute of Pathology, School of Medicine, Technical University of Munich, Munich, Germany;
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Katja Steiger
4Institute of Pathology, School of Medicine, Technical University of Munich, Munich, Germany;
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Timo Bartel
1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Essen, Germany;
2German Cancer Consortium, partner site University Hospital Essen, Essen, Germany;
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Benedikt M. Schaarschmidt
5Department of Diagnostic and Interventional Radiology, University Hospital Essen, University of Duisburg–Essen, Essen Germany;
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Aleksandar Milosevic
5Department of Diagnostic and Interventional Radiology, University Hospital Essen, University of Duisburg–Essen, Essen Germany;
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Robert Seifert
1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Essen, Germany;
2German Cancer Consortium, partner site University Hospital Essen, Essen, Germany;
6Department of Nuclear Medicine, University Hospital Münster, Münster, Germany;
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Michael Nader
1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Essen, Germany;
2German Cancer Consortium, partner site University Hospital Essen, Essen, Germany;
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Lukas Kessler
1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Essen, Germany;
2German Cancer Consortium, partner site University Hospital Essen, Essen, Germany;
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Jens T. Siveke
2German Cancer Consortium, partner site University Hospital Essen, Essen, Germany;
3Division of Solid Tumor Translational Oncology, German Cancer Research Center, Heidelberg, Germany;
7Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany;
8Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany;
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Katharina Lueckerath
1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Essen, Germany;
2German Cancer Consortium, partner site University Hospital Essen, Essen, Germany;
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Stefan Kasper
2German Cancer Consortium, partner site University Hospital Essen, Essen, Germany;
7Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany;
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Ken Herrmann
1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Essen, Germany;
2German Cancer Consortium, partner site University Hospital Essen, Essen, Germany;
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Nader Hirmas
1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Essen, Germany;
2German Cancer Consortium, partner site University Hospital Essen, Essen, Germany;
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Hartmut H. Schmidt
9Medical Clinic B, Department of Gastroenterology, Hepatology, Endocrinology, and Infectiology, University Hospital Münster, Münster, Germany; and
10Department of Gastroenterology and Hepatology, University Hospital Duisburg–Essen, Essen, Germany
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Rainer Hamacher
2German Cancer Consortium, partner site University Hospital Essen, Essen, Germany;
7Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany;
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Wolfgang P. Fendler
1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, Essen, Germany;
2German Cancer Consortium, partner site University Hospital Essen, Essen, Germany;
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Journal of Nuclear Medicine: 64 (7)
Journal of Nuclear Medicine
Vol. 64, Issue 7
July 1, 2023
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Superior Tumor Detection for 68Ga-FAPI-46 Versus 18F-FDG PET/CT and Conventional CT in Patients with Cholangiocarcinoma
Kim M. Pabst, Marija Trajkovic-Arsic, Phyllis F.Y. Cheung, Simone Ballke, Katja Steiger, Timo Bartel, Benedikt M. Schaarschmidt, Aleksandar Milosevic, Robert Seifert, Michael Nader, Lukas Kessler, Jens T. Siveke, Katharina Lueckerath, Stefan Kasper, Ken Herrmann, Nader Hirmas, Hartmut H. Schmidt, Rainer Hamacher, Wolfgang P. Fendler
Journal of Nuclear Medicine Jul 2023, 64 (7) 1049-1055; DOI: 10.2967/jnumed.122.265215

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Superior Tumor Detection for 68Ga-FAPI-46 Versus 18F-FDG PET/CT and Conventional CT in Patients with Cholangiocarcinoma
Kim M. Pabst, Marija Trajkovic-Arsic, Phyllis F.Y. Cheung, Simone Ballke, Katja Steiger, Timo Bartel, Benedikt M. Schaarschmidt, Aleksandar Milosevic, Robert Seifert, Michael Nader, Lukas Kessler, Jens T. Siveke, Katharina Lueckerath, Stefan Kasper, Ken Herrmann, Nader Hirmas, Hartmut H. Schmidt, Rainer Hamacher, Wolfgang P. Fendler
Journal of Nuclear Medicine Jul 2023, 64 (7) 1049-1055; DOI: 10.2967/jnumed.122.265215
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Keywords

  • 68Ga-FAPI-46 PET/CT
  • 18F-FDG PET/CT
  • conventional CT
  • cholangiocarcinoma
  • immunohistochemistry
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