Fast and Accurate Amyloid Brain PET Quantification Without MRI Using Deep Neural Networks

Seung Kwan Kang; Daewoon Kim; Seong A Shin; Yu Kyeong Kim; Hongyoon Choi; Jae Sung Lee

doi:10.2967/jnumed.122.264414

Research ArticleBasic Science Investigation

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Fast and Accurate Amyloid Brain PET Quantification Without MRI Using Deep Neural Networks

Seung Kwan Kang, Daewoon Kim, Seong A Shin, Yu Kyeong Kim, Hongyoon Choi and Jae Sung Lee

Journal of Nuclear Medicine April 2023, 64 (4) 659-666; DOI: https://doi.org/10.2967/jnumed.122.264414

Seung Kwan Kang

1Brightonix Imaging Inc., Seoul, Korea;

2Institute of Radiation Medicine, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea;

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Daewoon Kim

3Interdisciplinary Program of Bioengineering, Seoul National University, Seoul, Korea;

4Artificial Intelligence Institute, Seoul National University, Seoul, Korea;

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Seong A Shin

1Brightonix Imaging Inc., Seoul, Korea;

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Yu Kyeong Kim

5Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea; and

6Department of Nuclear Medicine, Seoul Metropolitan Government–Seoul National University Boramae Medical Center, Seoul, Korea

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Hongyoon Choi

2Institute of Radiation Medicine, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea;

5Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea; and

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Jae Sung Lee

1Brightonix Imaging Inc., Seoul, Korea;

2Institute of Radiation Medicine, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea;

3Interdisciplinary Program of Bioengineering, Seoul National University, Seoul, Korea;

4Artificial Intelligence Institute, Seoul National University, Seoul, Korea;

5Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea; and

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Vol. 64, Issue 4

April 1, 2023

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Fast and Accurate Amyloid Brain PET Quantification Without MRI Using Deep Neural Networks

Seung Kwan Kang, Daewoon Kim, Seong A Shin, Yu Kyeong Kim, Hongyoon Choi, Jae Sung Lee

Journal of Nuclear Medicine Apr 2023, 64 (4) 659-666; DOI: 10.2967/jnumed.122.264414

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Fast and Accurate Amyloid Brain PET Quantification Without MRI Using Deep Neural Networks

Seung Kwan Kang, Daewoon Kim, Seong A Shin, Yu Kyeong Kim, Hongyoon Choi, Jae Sung Lee

Journal of Nuclear Medicine Apr 2023, 64 (4) 659-666; DOI: 10.2967/jnumed.122.264414

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Keywords

amyloid PET
spatial normalization
deep learning
quantification

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