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Research ArticleBRIEF COMMUNICATION
Open Access

Safety and Survival Outcomes of 177Lu-Prostate-Specific Membrane Antigen Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer with Prior 223Ra treatment: The RALU Study

Kambiz Rahbar, Markus Essler, Kim M. Pabst, Matthias Eiber, Christian la Fougère, Vikas Prasad, Philipp Rassek, Ergela Hasa, Helmut Dittmann, Ralph A. Bundschuh, Wolfgang P. Fendler, Milena Kurtinecz, Anja Schmall, Frank Verholen and Oliver Sartor
Journal of Nuclear Medicine April 2023, 64 (4) 574-578; DOI: https://doi.org/10.2967/jnumed.122.264456
Kambiz Rahbar
1Department of Nuclear Medicine, University of Münster Medical Center, Münster, Germany;
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Markus Essler
2Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany;
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Kim M. Pabst
3Department of Nuclear Medicine, German Cancer Consortium (DKTK) University Hospital Essen, Essen, Germany;
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Matthias Eiber
4Department of Nuclear Medicine, Technical University of Munich, Munich, Germany;
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Christian la Fougère
5Department of Nuclear Medicine and Clinical Molecular Imaging, University Hospital Tübingen, Tübingen, Germany;
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Vikas Prasad
6Department of Nuclear Medicine, University of Ulm, Ulm, Germany;
7International Centers for Precision Oncology Foundation, Ravensburg, Germany;
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Philipp Rassek
1Department of Nuclear Medicine, University of Münster Medical Center, Münster, Germany;
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Ergela Hasa
4Department of Nuclear Medicine, Technical University of Munich, Munich, Germany;
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Helmut Dittmann
5Department of Nuclear Medicine and Clinical Molecular Imaging, University Hospital Tübingen, Tübingen, Germany;
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Ralph A. Bundschuh
8Department of Nuclear Medicine, Medical Faculty, University of Augsburg, Augsburg, Germany;
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Wolfgang P. Fendler
3Department of Nuclear Medicine, German Cancer Consortium (DKTK) University Hospital Essen, Essen, Germany;
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Milena Kurtinecz
9Bayer HealthCare Pharmaceuticals, Whippany, New Jersey;
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Anja Schmall
10Bayer Consumer Care, Basel, Switzerland; and
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Frank Verholen
10Bayer Consumer Care, Basel, Switzerland; and
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Oliver Sartor
11Tulane Cancer Center, Tulane Medical School, New Orleans, Louisiana
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Article Information

vol. 64 no. 4 574-578
DOI 
https://doi.org/10.2967/jnumed.122.264456
PubMed 
36302656

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication July 1, 2022
  • Revision received October 12, 2022
  • Published online April 3, 2023.

Article Versions

  • previous version (October 27, 2022 - 12:56).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2023 by the Society of Nuclear Medicine and Molecular Imaging. Immediate Open Access: Creative Commons Attribution 4.0 International License (CC BY) allows users to share and adapt with attribution, excluding materials credited to previous publications. License: https://creativecommons.org/licenses/by/4.0/. Details: http://jnm.snmjournals.org/site/misc/permission.xhtml.

Author Information

  1. Kambiz Rahbar1,
  2. Markus Essler2,
  3. Kim M. Pabst3,
  4. Matthias Eiber4,
  5. Christian la Fougère5,
  6. Vikas Prasad6,7,
  7. Philipp Rassek1,
  8. Ergela Hasa4,
  9. Helmut Dittmann5,
  10. Ralph A. Bundschuh8,
  11. Wolfgang P. Fendler3,
  12. Milena Kurtinecz9,
  13. Anja Schmall10,
  14. Frank Verholen10 and
  15. Oliver Sartor11
  1. 1Department of Nuclear Medicine, University of Münster Medical Center, Münster, Germany;
  2. 2Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany;
  3. 3Department of Nuclear Medicine, German Cancer Consortium (DKTK) University Hospital Essen, Essen, Germany;
  4. 4Department of Nuclear Medicine, Technical University of Munich, Munich, Germany;
  5. 5Department of Nuclear Medicine and Clinical Molecular Imaging, University Hospital Tübingen, Tübingen, Germany;
  6. 6Department of Nuclear Medicine, University of Ulm, Ulm, Germany;
  7. 7International Centers for Precision Oncology Foundation, Ravensburg, Germany;
  8. 8Department of Nuclear Medicine, Medical Faculty, University of Augsburg, Augsburg, Germany;
  9. 9Bayer HealthCare Pharmaceuticals, Whippany, New Jersey;
  10. 10Bayer Consumer Care, Basel, Switzerland; and
  11. 11Tulane Cancer Center, Tulane Medical School, New Orleans, Louisiana
  1. For correspondence or reprints, contact Kambiz Rahbar (kambiz.rahbar{at}ukmuenster.de).
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Journal of Nuclear Medicine: 64 (4)
Journal of Nuclear Medicine
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April 1, 2023
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Safety and Survival Outcomes of 177Lu-Prostate-Specific Membrane Antigen Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer with Prior 223Ra treatment: The RALU Study
Kambiz Rahbar, Markus Essler, Kim M. Pabst, Matthias Eiber, Christian la Fougère, Vikas Prasad, Philipp Rassek, Ergela Hasa, Helmut Dittmann, Ralph A. Bundschuh, Wolfgang P. Fendler, Milena Kurtinecz, Anja Schmall, Frank Verholen, Oliver Sartor
Journal of Nuclear Medicine Apr 2023, 64 (4) 574-578; DOI: 10.2967/jnumed.122.264456

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Safety and Survival Outcomes of 177Lu-Prostate-Specific Membrane Antigen Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer with Prior 223Ra treatment: The RALU Study
Kambiz Rahbar, Markus Essler, Kim M. Pabst, Matthias Eiber, Christian la Fougère, Vikas Prasad, Philipp Rassek, Ergela Hasa, Helmut Dittmann, Ralph A. Bundschuh, Wolfgang P. Fendler, Milena Kurtinecz, Anja Schmall, Frank Verholen, Oliver Sartor
Journal of Nuclear Medicine Apr 2023, 64 (4) 574-578; DOI: 10.2967/jnumed.122.264456
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  • 177Lu-Prostate-Specific Membrane Antigen Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer and Prior 223Ra (RALU Study)
  • Sequential and Combination Therapies of 223RaCl2 and Prostate-Specific Membrane Antigen Radioligand Therapy
  • SNMMI Consensus Statement on Patient Selection and Appropriate Use of 177Lu-PSMA-617 Radionuclide Therapy
  • SNMMI Consensus Statement on Patient Selection and Appropriate Use of 177Lu-PSMA-617 Radionuclide Therapy
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Keywords

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