targeted α-therapy

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First-in-Human Phase 0 Study of AB001, a Prostate-Specific Membrane Antigen–Targeted ²¹²Pb Radioligand, in Patients with Metastatic Castration-Resistant Prostate Cancer
Kjetil Berner, Eivor Hernes, Monika Kvassheim, Mona-Elisabeth Revheim, Julie Bastiansen, Silje Selboe, Charlotte L. Bakken, Simen R. Grønningsæter, Øyvind S. Bruland, Roy H. Larsen, Lily Bouzelmat, Vicki L. Jardine and Caroline Stokke

Journal of Nuclear Medicine May 1, 2025, 66 (5) 732-738; DOI: https://doi.org/10.2967/jnumed.124.269299
Open Access
Side-by-Side Comparison of the In Vivo Performance of [²¹²Pb]Pb-DOTAMTATE and Other SSTR2-Targeting Compounds
Amal Saidi, Tania A. Stallons, Amy G. Wong, Aaron T. Schatzmann, Ugur Soysal and Julien J. Torgue

Journal of Nuclear Medicine March 1, 2025, 66 (3) 391-397; DOI: https://doi.org/10.2967/jnumed.124.268345
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Preclinical Evaluation of ²²⁶Ac as a Theranostic Agent: Imaging, Dosimetry, and Therapy
Helena Koniar, Luke Wharton, Aidan Ingham, Ana Paulina Morales Oliver, Helen Merkens, Cristina Rodríguez-Rodríguez, Peter Kunz, Valery Radchenko, Hua Yang, Arman Rahmim, Carlos Uribe and Paul Schaffer

Journal of Nuclear Medicine November 1, 2024, 65 (11) 1762-1768; DOI: https://doi.org/10.2967/jnumed.124.267999
Open Access
Preclinical Investigation of [²¹²Pb]Pb-DOTAM-GRPR1 for Peptide Receptor Radionuclide Therapy in a Prostate Tumor Model
Amal Saidi, Tania A. Stallons, Amy G. Wong and Julien J. Torgue

Journal of Nuclear Medicine November 1, 2024, 65 (11) 1769-1775; DOI: https://doi.org/10.2967/jnumed.124.268101
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Development of a ²¹³Bi-Labeled Pyridyl Benzofuran for Targeted α-Therapy of Amyloid-β Aggregates
Aidan A. Bender, Emily K. Kirkeby, Donna J. Cross, Satoshi Minoshima, Andrew G. Roberts and Tara E. Mastren

Journal of Nuclear Medicine September 1, 2024, 65 (9) 1467-1472; DOI: https://doi.org/10.2967/jnumed.124.267482
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Development and Preclinical Evaluation of [²¹¹At]PSAt-3-Ga: An Inhibitor for Targeted α-Therapy of Prostate Cancer
Mohamed El Fakiri, Nawal Ayada, Marius Müller, Lars Hvass, Teodor H. Gamzov, Anne Skovsbo Clausen, Nicolas M. Geis, Nils Steinacker, Ellinor Hansson, Sture Lindegren, Emma Aneheim, Holger Jensen, Ann-Christin Eder, Andreas I. Jensen, Christian B.M. Poulie, Andreas Kjaer, Matthias Eder and Matthias M. Herth

Journal of Nuclear Medicine April 1, 2024, 65 (4) 593-599; DOI: https://doi.org/10.2967/jnumed.123.267043
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²¹²Pb-Pretargeted Theranostics for Pancreatic Cancer
David Bauer, Lukas M. Carter, Mohamed I. Atmane, Roberto De Gregorio, Alexa Michel, Spencer Kaminsky, Sebastien Monette, Mengshi Li, Michael K. Schultz and Jason S. Lewis

Journal of Nuclear Medicine January 1, 2024, 65 (1) 109-116; DOI: https://doi.org/10.2967/jnumed.123.266388
Open Access
¹⁷⁷Lu-Prostate-Specific Membrane Antigen Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer and Prior ²²³Ra (RALU Study)
Kambiz Rahbar, Markus Essler, Matthias Eiber, Christian la Fougère, Vikas Prasad, Wolfgang P. Fendler, Philipp Rassek, Ergela Hasa, Helmut Dittmann, Ralph A. Bundschuh, Kim M. Pabst, Milena Kurtinecz, Anja Schmall, Frank Verholen and Oliver Sartor

Journal of Nuclear Medicine December 1, 2023, 64 (12) 1925-1931; DOI: https://doi.org/10.2967/jnumed.123.266125
Open Access
Immuno-PET and Targeted α-Therapy Using Anti–Glypican-1 Antibody Labeled with ⁸⁹Zr or ²¹¹At: A Theranostic Approach for Pancreatic Ductal Adenocarcinoma
Tadashi Watabe, Kazuya Kabayama, Sadahiro Naka, Ryuku Yamamoto, Kazuko Kaneda, Satoshi Serada, Kazuhiro Ooe, Atsushi Toyoshima, Yang Wang, Hiromitsu Haba, Kenta Kurimoto, Takanori Kobayashi, Eku Shimosegawa, Noriyuki Tomiyama, Koichi Fukase and Tetsuji Naka

Journal of Nuclear Medicine December 1, 2023, 64 (12) 1949-1955; DOI: https://doi.org/10.2967/jnumed.123.266313
Open Access
Pain Outcomes in Patients with Metastatic Castration-Resistant Prostate Cancer Treated with ²²³Ra: PARABO, a Prospective, Noninterventional Study
Holger Palmedo, Hojjat Ahmadzadehfar, Susanne Eschmann, Andreas Niesen, Johann Schönberger, Vahé Barsegian, Knut Liepe, Felix M. Mottaghy, Rongjin Guan, Joerg Pinkert, Per Sandström and Ken Herrmann

Journal of Nuclear Medicine September 1, 2023, 64 (9) 1392-1398; DOI: https://doi.org/10.2967/jnumed.123.265557

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