Gadolinium-Based Nanoparticles Sensitize Ovarian Peritoneal Carcinomatosis to Targeted Radionuclide Therapy

Clara Diaz Garcia-Prada; Léna Carmes; Salima Atis; Ali Parach; Alejandro Bertolet; Marta Jarlier; Sophie Poty; Daniel Suarez Garcia; Wook-Geun Shin; Stanislas Du Manoir; Jan Schuemann; Olivier Tillement; François Lux; Julie Constanzo; Jean-Pierre Pouget

doi:10.2967/jnumed.123.265418

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Gadolinium-Based Nanoparticles Sensitize Ovarian Peritoneal Carcinomatosis to Targeted Radionuclide Therapy

Clara Diaz Garcia-Prada, Léna Carmes, Salima Atis, Ali Parach, Alejandro Bertolet, Marta Jarlier, Sophie Poty, Daniel Suarez Garcia, Wook-Geun Shin, Stanislas Du Manoir, Jan Schuemann, Olivier Tillement, François Lux, Julie Constanzo and Jean-Pierre Pouget

Journal of Nuclear Medicine December 2023, 64 (12) 1956-1964; DOI: https://doi.org/10.2967/jnumed.123.265418

Clara Diaz Garcia-Prada

1Institut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France;

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Léna Carmes

2Institut Lumière Matière, Université Claude Bernard Lyon 1, Villeurbanne, France;

3NH TherAguix S.A., Meylan, France;

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Salima Atis

1Institut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France;

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Ali Parach

1Institut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France;

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Alejandro Bertolet

4Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts;

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Marta Jarlier

5Biometrics Unit, Montpellier Cancer Institute, University of Montpellier, Montpellier, France; and

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Sophie Poty

1Institut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France;

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Daniel Suarez Garcia

4Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts;

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Wook-Geun Shin

4Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts;

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Stanislas Du Manoir

1Institut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France;

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Jan Schuemann

4Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts;

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Olivier Tillement

2Institut Lumière Matière, Université Claude Bernard Lyon 1, Villeurbanne, France;

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François Lux

2Institut Lumière Matière, Université Claude Bernard Lyon 1, Villeurbanne, France;

6Institut Universitaire de France, Paris, France

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Julie Constanzo

1Institut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France;

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Jean-Pierre Pouget

1Institut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France;

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Gadolinium-Based Nanoparticles Sensitize Ovarian Peritoneal Carcinomatosis to Targeted Radionuclide Therapy

Journal of Nuclear Medicine Dec 2023, 64 (12) 1956-1964; DOI: 10.2967/jnumed.123.265418

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Gadolinium-Based Nanoparticles Sensitize Ovarian Peritoneal Carcinomatosis to Targeted Radionuclide Therapy

Journal of Nuclear Medicine Dec 2023, 64 (12) 1956-1964; DOI: 10.2967/jnumed.123.265418

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Keywords

radiosensitization
radiopharmaceutical
radioimmunotherapy
TRT
ovarian cancer
Auger electrons

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