Journal of Nuclear Medicine: 64 (12)

December 1, 2023; Volume 64,Issue 12

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine December 1, 2023, 64 (12) 6A;

President’s Message

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A Strategic Approach to Advancing Nuclear Medicine and Molecular Imaging
Helen R. Nadel

Journal of Nuclear Medicine December 1, 2023, 64 (12) 1843-1844;

Editor’s Page

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The Hierarchy of SUVs: From Diagnostics to Therapeutics and the Pathway to Effective Theranostics
Michael S. Hofman

Journal of Nuclear Medicine December 1, 2023, 64 (12) 1845-1847; DOI: https://doi.org/10.2967/jnumed.123.266930

State of the Art

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Ethical Considerations for Artificial Intelligence in Medical Imaging: Data Collection, Development, and Evaluation
Jonathan Herington, Melissa D. McCradden, Kathleen Creel, Ronald Boellaard, Elizabeth C. Jones, Abhinav K. Jha, Arman Rahmim, Peter J.H. Scott, John J. Sunderland, Richard L. Wahl, Sven Zuehlsdorff and Babak Saboury

Journal of Nuclear Medicine December 1, 2023, 64 (12) 1848-1854; DOI: https://doi.org/10.2967/jnumed.123.266080

Hot Topics

Open Access
⁶¹Cu-Labeled Radiotracers: Alternative or Choice?
Melpomeni Fani and Guillaume P. Nicolas

Journal of Nuclear Medicine December 1, 2023, 64 (12) 1855-1857; DOI: https://doi.org/10.2967/jnumed.123.266171

Focus on Molecular Imaging

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Imaging Agents for PET of Inflammatory Bowel Disease: A Review
Farzaneh Rezazadeh, Aidan P. Kilcline and Nerissa T. Viola

Journal of Nuclear Medicine December 1, 2023, 64 (12) 1858-1864; DOI: https://doi.org/10.2967/jnumed.123.265935

Oncology

Clinical
- BRIEF COMMUNICATION
  - $Molecular Markers Are Associated with Onset of Radioiodine Refractoriness in Patients with Papillary Thyroid Carcinoma$
    
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    Molecular Markers Are Associated with Onset of Radioiodine Refractoriness in Patients with Papillary Thyroid Carcinoma
    Christina Laschinsky, Sarah Theurer, Thomas Herold, Josefine Rawitzer, Frank Weber, Ken Herrmann, Tim Brandenburg, Dagmar Führer-Sakel, Wolfgang P. Fendler and Manuel Weber
    
    Journal of Nuclear Medicine December 1, 2023, 64 (12) 1865-1868; DOI: https://doi.org/10.2967/jnumed.123.266044
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  PSMA PET/CT for Response Assessment and Overall Survival Prediction in Patients with Metastatic Castration-Resistant Prostate Cancer Treated with Androgen Receptor Pathway Inhibitors
  Qaid Ahmed Shagera, Ioannis Karfis, Paulus Kristanto, Sideris Spyridon, Romain Diamand, Albert Santapau, Alexandre Peltier, Thierry Roumeguère, Patrick Flamen and Carlos Artigas
  
  Journal of Nuclear Medicine December 1, 2023, 64 (12) 1869-1875; DOI: https://doi.org/10.2967/jnumed.123.265874
- BRIEF COMMUNICATION
  - Open Access
    ChatGPT: Can You Prepare My Patients for [¹⁸F]FDG PET/CT and Explain My Reports?
    Julian M.M. Rogasch, Giulia Metzger, Martina Preisler, Markus Galler, Felix Thiele, Winfried Brenner, Felix Feldhaus, Christoph Wetz, Holger Amthauer, Christian Furth and Imke Schatka
    
    Journal of Nuclear Medicine December 1, 2023, 64 (12) 1876-1879; DOI: https://doi.org/10.2967/jnumed.123.266114
- FEATURED CLINICAL INVESTIGATION ARTICLE
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    First-in-Humans PET Imaging of KRAS^G12C Mutation Status in Non–Small Cell Lung and Colorectal Cancer Patients Using [¹⁸F]PFPMD
    Xiang Li, Jiajun Ye, Jingyi Wang, Zhiyong Quan, Guiyu Li, Wenhui Ma, Mingru Zhang, Weidong Yang, Junling Wang, Taoqi Ma, Fei Kang and Jing Wang
    
    Journal of Nuclear Medicine December 1, 2023, 64 (12) 1880-1888; DOI: https://doi.org/10.2967/jnumed.123.265715
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  Chemokine Receptor PET/CT Provides Relevant Staging and Management Changes in Marginal Zone Lymphoma
  Johannes Duell, Andreas K. Buck, Philipp E. Hartrampf, Wiebke Schlötelburg, Simone Schneid, Alexander Weich, Niklas Dreher, Constantin Lapa, Malte Kircher, Takahiro Higuchi, Samuel Samnick, Sebastian E. Serfling, Markus Raderer, Leo Rasche, Hermann Einsele, Max S. Topp, Aleksander Kosmala and Rudolf A. Werner
  
  Journal of Nuclear Medicine December 1, 2023, 64 (12) 1889-1894; DOI: https://doi.org/10.2967/jnumed.123.266074

Theranostics

Clinical
- BRIEF COMMUNICATION
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    Somatostatin Receptor Expression in Lung Neuroendocrine Tumors: An Analysis of DOTATATE PET Scans
    Taymeyah Al-Toubah, Jaime Montilla-Soler, Ghassan El-Haddad, Mintallah Haider and Jonathan Strosberg
    
    Journal of Nuclear Medicine December 1, 2023, 64 (12) 1895-1898; DOI: https://doi.org/10.2967/jnumed.123.266185
- Open Access
  ⁶⁸Ga-Labeled Fibroblast Activation Protein Inhibitor PET/CT for the Early and Late Prediction of Pathologic Response to Neoadjuvant Chemotherapy in Breast Cancer Patients: A Prospective Study
  Ling Chen, Shan Zheng, Linying Chen, Sunwang Xu, Kunlin Wu, Lingjun Kong, Jiajie Xue, Xiangjin Chen, Weibing Miao and Youzhi Zhu
  
  Journal of Nuclear Medicine December 1, 2023, 64 (12) 1899-1905; DOI: https://doi.org/10.2967/jnumed.123.266079
- BRIEF COMMUNICATION
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    Oncologic Staging with ⁶⁸Ga-FAPI PET/CT Demonstrates a Lower Rate of Nonspecific Lymph Node Findings Than ¹⁸F-FDG PET/CT
    Tristan T. Demmert, Kelsey L. Pomykala, Helena Lanzafame, Kim M. Pabst, Katharina Lueckerath, Jens Siveke, Lale Umutlu, Hubertus Hautzel, Rainer Hamacher, Ken Herrmann and Wolfgang P. Fendler
    
    Journal of Nuclear Medicine December 1, 2023, 64 (12) 1906-1909; DOI: https://doi.org/10.2967/jnumed.123.265751
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  ⁶⁸Ga-Labeled Fibroblast Activation Protein Inhibitor (⁶⁸Ga-FAPI) PET for Pancreatic Adenocarcinoma: Data from the ⁶⁸Ga-FAPI PET Observational Trial
  Lukas Kessler, Nader Hirmas, Kim M. Pabst, Rainer Hamacher, Justin Ferdinandus, Benedikt M. Schaarschmidt, Aleksandar Milosevic, Michael Nader, Lale Umutlu, Waldemar Uhl, Anke Reinacher-Schick, Celine Lugnier, David Witte, Marco Niedergethmann, Ken Herrmann, Wolfgang P. Fendler and Jens T. Siveke
  
  Journal of Nuclear Medicine December 1, 2023, 64 (12) 1910-1917; DOI: https://doi.org/10.2967/jnumed.122.264827
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  An Intrapatient Dosimetry Comparison of ¹⁷⁷Lu-rhPSMA-10.1 and ¹⁷⁷Lu-PSMA-I&T in Patients with Metastatic Castration-Resistant Prostate Cancer
  Andreas Rinscheid, Alexander Gäble, Georgine Wienand, Christian Pfob, Alexander Dierks, Malte Kircher, Martin Trepel, Dorothea Weckermann, Constantin Lapa and Ralph A. Bundschuh
  
  Journal of Nuclear Medicine December 1, 2023, 64 (12) 1918-1924; DOI: https://doi.org/10.2967/jnumed.123.265970
- Open Access
  ¹⁷⁷Lu-Prostate-Specific Membrane Antigen Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer and Prior ²²³Ra (RALU Study)
  Kambiz Rahbar, Markus Essler, Matthias Eiber, Christian la Fougère, Vikas Prasad, Wolfgang P. Fendler, Philipp Rassek, Ergela Hasa, Helmut Dittmann, Ralph A. Bundschuh, Kim M. Pabst, Milena Kurtinecz, Anja Schmall, Frank Verholen and Oliver Sartor
  
  Journal of Nuclear Medicine December 1, 2023, 64 (12) 1925-1931; DOI: https://doi.org/10.2967/jnumed.123.266125
- INVITED PERSPECTIVE
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    Sequential and Combination Therapies of ²²³RaCl₂ and Prostate-Specific Membrane Antigen Radioligand Therapy
    Hossein Jadvar
    
    Journal of Nuclear Medicine December 1, 2023, 64 (12) 1932-1933; DOI: https://doi.org/10.2967/jnumed.123.266427
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  Tumor-Targeted Interleukin 2 Boosts the Anticancer Activity of FAP-Directed Radioligand Therapeutics
  Andrea Galbiati, Paulina Dorten, Ettore Gilardoni, Florian Gierse, Matilde Bocci, Aureliano Zana, Jacqueline Mock, Michael Claesener, Juela Cufe, Florian Büther, Klaus Schäfers, Sven Hermann, Michael Schäfers, Dario Neri, Samuele Cazzamalli and Philipp Backhaus
  
  Journal of Nuclear Medicine December 1, 2023, 64 (12) 1934-1940; DOI: https://doi.org/10.2967/jnumed.123.266007
Basic
- Open Access
  Preclinical Evaluation of a Radiotheranostic Single-Domain Antibody Against Fibroblast Activation Protein α
  Yana Dekempeneer, Sam Massa, Francis Santens, Laurent Navarro, Marion Berdal, Melissa Miranda Lucero, Ana Rita Pombo Antunes, Tony Lahoutte, Jo A. Van Ginderachter, Nick Devoogdt and Matthias D’Huyvetter
  
  Journal of Nuclear Medicine December 1, 2023, 64 (12) 1941-1948; DOI: https://doi.org/10.2967/jnumed.123.266381
- Open Access
  Immuno-PET and Targeted α-Therapy Using Anti–Glypican-1 Antibody Labeled with ⁸⁹Zr or ²¹¹At: A Theranostic Approach for Pancreatic Ductal Adenocarcinoma
  Tadashi Watabe, Kazuya Kabayama, Sadahiro Naka, Ryuku Yamamoto, Kazuko Kaneda, Satoshi Serada, Kazuhiro Ooe, Atsushi Toyoshima, Yang Wang, Hiromitsu Haba, Kenta Kurimoto, Takanori Kobayashi, Eku Shimosegawa, Noriyuki Tomiyama, Koichi Fukase and Tetsuji Naka
  
  Journal of Nuclear Medicine December 1, 2023, 64 (12) 1949-1955; DOI: https://doi.org/10.2967/jnumed.123.266313
- FEATURED ARTICLE OF THE MONTH
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    Gadolinium-Based Nanoparticles Sensitize Ovarian Peritoneal Carcinomatosis to Targeted Radionuclide Therapy
    Clara Diaz Garcia-Prada, Léna Carmes, Salima Atis, Ali Parach, Alejandro Bertolet, Marta Jarlier, Sophie Poty, Daniel Suarez Garcia, Wook-Geun Shin, Stanislas Du Manoir, Jan Schuemann, Olivier Tillement, François Lux, Julie Constanzo and Jean-Pierre Pouget
    
    Journal of Nuclear Medicine December 1, 2023, 64 (12) 1956-1964; DOI: https://doi.org/10.2967/jnumed.123.265418

Radionuclide Therapy

Basic
- Open Access
  [¹²³I]CC1: A PARP-Targeting, Auger Electron–Emitting Radiopharmaceutical for Radionuclide Therapy of Cancer
  Chung Ying Chan, Zijun Chen, Florian Guibbal, Gemma Dias, Gianluca Destro, Edward O’Neill, Mathew Veal, Doreen Lau, Michael Mosley, Thomas C. Wilson, Véronique Gouverneur and Bart Cornelissen
  
  Journal of Nuclear Medicine December 1, 2023, 64 (12) 1965-1971; DOI: https://doi.org/10.2967/jnumed.123.265429

Radiobiology/Dosimetry

Clinical
- Open Access
  Clinical Characterization of [¹⁸F]T-008, a Cholesterol 24-Hydroxylase PET Ligand: Dosimetry, Kinetic Modeling, Variability, and Soticlestat Occupancy
  Cristian C. Constantinescu, Terry Brown, Shining Wang, Wei Yin, Olivier Barret, Danna Jennings and Johannes Tauscher
  
  Journal of Nuclear Medicine December 1, 2023, 64 (12) 1972-1979; DOI: https://doi.org/10.2967/jnumed.123.265912

Neurology

Clinical
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  [¹⁸F]PI-2620 Binding Patterns in Patients with Suspected Alzheimer Disease and Frontotemporal Lobar Degeneration
  Ganna Blazhenets, David N. Soleimani-Meigooni, Wesley Thomas, Nidhi Mundada, Matthias Brendel, Stephanie Vento, Lawren VandeVrede, Hilary W. Heuer, Peter Ljubenkov, Julio C. Rojas, Miranda K. Chen, Alinda N. Amuiri, Zachary Miller, Maria L. Gorno-Tempini, Bruce L. Miller, Howie J. Rosen, Irene Litvan, Murray Grossman, Brad Boeve, Alexander Pantelyat, Maria Carmela Tartaglia, David J. Irwin, Brad C. Dickerson, Suzanne L. Baker, Adam L. Boxer, Gil D. Rabinovici and Renaud La Joie
  
  Journal of Nuclear Medicine December 1, 2023, 64 (12) 1980-1989; DOI: https://doi.org/10.2967/jnumed.123.265856

Physics and Instrumentation

Basic
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  Performance Characteristics of a New-Generation Digital Bismuth Germanium Oxide PET/CT System, Omni Legend 32, According to NEMA NU 2-2018 Standards
  Shin Yamagishi, Kenta Miwa, Shun Kamitaki, Kouichi Anraku, Shun Sato, Tensho Yamao, Hitoshi Kubo, Noriaki Miyaji and Kazuhiro Oguchi
  
  Journal of Nuclear Medicine December 1, 2023, 64 (12) 1990-1997; DOI: https://doi.org/10.2967/jnumed.123.266140

Special Contribution

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One Hundred Years of the Tracer Principle
Sebastian Hoberück, Klaus Zöphel, Martin G. Pomper, Steven P. Rowe and Andrei Gafita

Journal of Nuclear Medicine December 1, 2023, 64 (12) 1998-2000; DOI: https://doi.org/10.2967/jnumed.123.266458

Illustrated Post

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Somatostatin Receptor Antagonists as a Theranostic Option in Iodine-Refractory Thyroid Carcinoma
Johanna S. Enke, Ralph A. Bundschuh, Georgine Wienand, Nic G. Reitsam, Malte Kircher, Christian H. Pfob, Constantin Lapa and Alexander Dierks

Journal of Nuclear Medicine December 1, 2023, 64 (12) 2001; DOI: https://doi.org/10.2967/jnumed.123.265639

Letters to the Editor

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Theranostics Is Not Radiotheranostics
Weijun Wei

Journal of Nuclear Medicine December 1, 2023, 64 (12) 2002; DOI: https://doi.org/10.2967/jnumed.123.266292
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Reply to “Theranostics Is Not Radiotheranostics”
Wolfgang Andreas Weber

Journal of Nuclear Medicine December 1, 2023, 64 (12) 2002; DOI: https://doi.org/10.2967/jnumed.123.266491

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Table of Contents

This Month in JNM

President’s Message

Editor’s Page

State of the Art

Hot Topics

Focus on Molecular Imaging

Oncology

Clinical

BRIEF COMMUNICATION

BRIEF COMMUNICATION

FEATURED CLINICAL INVESTIGATION ARTICLE

Theranostics

Clinical

BRIEF COMMUNICATION

BRIEF COMMUNICATION

INVITED PERSPECTIVE

Basic

FEATURED ARTICLE OF THE MONTH

Radionuclide Therapy

Basic

Radiobiology/Dosimetry

Clinical

Neurology

Clinical

Physics and Instrumentation

Basic

Special Contribution

Illustrated Post

Letters to the Editor

In this issue

Issue highlights

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