Lesion Dosimetry for [177Lu]Lu-PSMA-617 Radiopharmaceutical Therapy Combined with Stereotactic Body Radiotherapy in Patients with Oligometastatic Castration-Sensitive Prostate Cancer

Milan Grkovski; Joseph A. O’Donoghue; Brandon S. Imber; George Andl; Cheng Tu; Daniel Lafontaine; Jazmin Schwartz; Maria Thor; Michael J. Zelefsky; John L. Humm; Lisa Bodei

doi:10.2967/jnumed.123.265763

Research ArticleClinical Investigation

Lesion Dosimetry for [¹⁷⁷Lu]Lu-PSMA-617 Radiopharmaceutical Therapy Combined with Stereotactic Body Radiotherapy in Patients with Oligometastatic Castration-Sensitive Prostate Cancer

Milan Grkovski, Joseph A. O’Donoghue, Brandon S. Imber, George Andl, Cheng Tu, Daniel Lafontaine, Jazmin Schwartz, Maria Thor, Michael J. Zelefsky, John L. Humm and Lisa Bodei

Journal of Nuclear Medicine November 2023, 64 (11) 1779-1787; DOI: https://doi.org/10.2967/jnumed.123.265763

Milan Grkovski

1Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York;

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Joseph A. O’Donoghue

1Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York;

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Brandon S. Imber

2Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York;

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George Andl

3Varian Medical Systems Inc., Palo Alto, California; and

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Cheng Tu

3Varian Medical Systems Inc., Palo Alto, California; and

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Daniel Lafontaine

1Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York;

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Jazmin Schwartz

1Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York;

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Maria Thor

1Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York;

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Michael J. Zelefsky

2Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York;

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John L. Humm

1Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York;

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Lisa Bodei

4Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York

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Journal of Nuclear Medicine

Vol. 64, Issue 11

November 1, 2023

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Lesion Dosimetry for [¹⁷⁷Lu]Lu-PSMA-617 Radiopharmaceutical Therapy Combined with Stereotactic Body Radiotherapy in Patients with Oligometastatic Castration-Sensitive Prostate Cancer

Milan Grkovski, Joseph A. O’Donoghue, Brandon S. Imber, George Andl, Cheng Tu, Daniel Lafontaine, Jazmin Schwartz, Maria Thor, Michael J. Zelefsky, John L. Humm, Lisa Bodei

Journal of Nuclear Medicine Nov 2023, 64 (11) 1779-1787; DOI: 10.2967/jnumed.123.265763

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Lesion Dosimetry for [¹⁷⁷Lu]Lu-PSMA-617 Radiopharmaceutical Therapy Combined with Stereotactic Body Radiotherapy in Patients with Oligometastatic Castration-Sensitive Prostate Cancer

Milan Grkovski, Joseph A. O’Donoghue, Brandon S. Imber, George Andl, Cheng Tu, Daniel Lafontaine, Jazmin Schwartz, Maria Thor, Michael J. Zelefsky, John L. Humm, Lisa Bodei

Journal of Nuclear Medicine Nov 2023, 64 (11) 1779-1787; DOI: 10.2967/jnumed.123.265763

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Keywords

prostate cancer
oligometastasis
[177Lu]Lu-PSMA-617
dosimetry
SBRT
biologically effective dose

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