The Impact of Peptide Amount on Tumor Uptake to Assess PSMA Receptor Saturation on 68Ga-PSMA-11 PET/CT in Patients with Primary Prostate Cancer

Hinke Siebinga; Judith olde Heuvel; Erik-Jan Rijkhorst; Jeroen J.M.A. Hendrikx; Berlinda J. de Wit-van der Veen

doi:10.2967/jnumed.122.264101

Research ArticleClinical Investigation

The Impact of Peptide Amount on Tumor Uptake to Assess PSMA Receptor Saturation on ⁶⁸Ga-PSMA-11 PET/CT in Patients with Primary Prostate Cancer

Hinke Siebinga, Judith olde Heuvel, Erik-Jan Rijkhorst, Jeroen J.M.A. Hendrikx and Berlinda J. de Wit-van der Veen

Journal of Nuclear Medicine January 2023, 64 (1) 63-68; DOI: https://doi.org/10.2967/jnumed.122.264101

Hinke Siebinga

1Department of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands;

2Department of Pharmacy and Pharmacology, Netherlands Cancer Institute, Amsterdam, The Netherlands; and

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Judith olde Heuvel

1Department of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands;

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Erik-Jan Rijkhorst

3Department of Medical Physics and Technology, Netherlands Cancer Institute, Amsterdam, The Netherlands

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Jeroen J.M.A. Hendrikx

1Department of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands;

2Department of Pharmacy and Pharmacology, Netherlands Cancer Institute, Amsterdam, The Netherlands; and

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Berlinda J. de Wit-van der Veen

1Department of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands;

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vol. 64 no. 1 63-68

DOI

https://doi.org/10.2967/jnumed.122.264101

PubMed

35680416

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Society of Nuclear Medicine

Print ISSN

0161-5505

Online ISSN

2159-662X

History

Received for publication March 4, 2022
Revision received June 2, 2022
Published online January 4, 2023.

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Author Information

Hinke Siebinga¹,²,
Judith olde Heuvel¹,
Erik-Jan Rijkhorst³,
Jeroen J.M.A. Hendrikx¹,² and
Berlinda J. de Wit-van der Veen¹

¹Department of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands;
²Department of Pharmacy and Pharmacology, Netherlands Cancer Institute, Amsterdam, The Netherlands; and
³Department of Medical Physics and Technology, Netherlands Cancer Institute, Amsterdam, The Netherlands

For correspondence or reprints, contact Berlinda J. de Wit-van der Veen (l.vd.veen{at}nki.nl).

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The Impact of Peptide Amount on Tumor Uptake to Assess PSMA Receptor Saturation on ⁶⁸Ga-PSMA-11 PET/CT in Patients with Primary Prostate Cancer

Hinke Siebinga, Judith olde Heuvel, Erik-Jan Rijkhorst, Jeroen J.M.A. Hendrikx, Berlinda J. de Wit-van der Veen

Journal of Nuclear Medicine Jan 2023, 64 (1) 63-68; DOI: 10.2967/jnumed.122.264101

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The Impact of Peptide Amount on Tumor Uptake to Assess PSMA Receptor Saturation on ⁶⁸Ga-PSMA-11 PET/CT in Patients with Primary Prostate Cancer

Hinke Siebinga, Judith olde Heuvel, Erik-Jan Rijkhorst, Jeroen J.M.A. Hendrikx, Berlinda J. de Wit-van der Veen

Journal of Nuclear Medicine Jan 2023, 64 (1) 63-68; DOI: 10.2967/jnumed.122.264101

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Keywords

PSMA
prostate cancer
peptide amount
receptor saturation
specific activity

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The Impact of Peptide Amount on Tumor Uptake to Assess PSMA Receptor Saturation on ⁶⁸Ga-PSMA-11 PET/CT in Patients with Primary Prostate Cancer

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