Table of Contents

January 1, 2023; Volume 64,Issue 1

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine January 1, 2023, 64 (1) 8A;

Editor’s Page

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Thank You Drs. Ziessman and Knight for Your Many Years of Newsline Coverage
Johannes Czernin

Journal of Nuclear Medicine January 1, 2023, 64 (1) 1;

Highlights

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2022 SNMMI Highlights Lecture: Oncology and Therapy, Part 2
Heiko Schöder

Journal of Nuclear Medicine January 1, 2023, 64 (1) 2-7; DOI: https://doi.org/10.2967/jnumed.122.265202

Discussions with Leaders

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From Physician to Leader in Global Research and Development
Ken Song, Lisa Bodei and Johannes Czernin

Journal of Nuclear Medicine January 1, 2023, 64 (1) 8-11; DOI: https://doi.org/10.2967/jnumed.122.265135

The State of the Art

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Imaging Biomarkers for Central Nervous System Drug Development and Future Clinical Utility: Lessons from Neurodegenerative Disorders
John P. Seibyl

Journal of Nuclear Medicine January 1, 2023, 64 (1) 12-19; DOI: https://doi.org/10.2967/jnumed.122.264773

Continuing Education

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Brain Trauma Imaging
Gérard N. Bischof and Donna J. Cross

Journal of Nuclear Medicine January 1, 2023, 64 (1) 20-29; DOI: https://doi.org/10.2967/jnumed.121.263293

Focus on Molecular Imaging

Open Access
Imaging of Activated T Cells
Mohammad O. Sako and Benjamin M. Larimer

Journal of Nuclear Medicine January 1, 2023, 64 (1) 30-33; DOI: https://doi.org/10.2967/jnumed.122.264097

Theranostics

Clinical
- FEATURED ARTICLE OF THE MONTH
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    C-X-C Motif Chemokine Receptor 4–Targeted Radioligand Therapy in Patients with Advanced T-Cell Lymphoma
    Andreas K. Buck, Götz Ulrich Grigoleit, Sabrina Kraus, Andreas Schirbel, Michael Heinsch, Niklas Dreher, Takahiro Higuchi, Constantin Lapa, Heribert Hänscheid, Samuel Samnick, Hermann Einsele, Sebastian E. Serfling and Rudolf A. Werner
    
    Journal of Nuclear Medicine January 1, 2023, 64 (1) 34-39; DOI: https://doi.org/10.2967/jnumed.122.264207
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  Long-Term Outcomes of Submaximal Activities of Peptide Receptor Radionuclide Therapy with ¹⁷⁷Lu-DOTATATE in Neuroendocrine Tumor Patients
  Noémie S. Minczeles, Wouter W. de Herder, Richard A. Feelders, Frederik A. Verburg, Johannes Hofland and Tessa Brabander
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 40-46; DOI: https://doi.org/10.2967/jnumed.122.263856
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  A 2022 International Survey on the Status of Prostate Cancer Theranostics
  Thomas Beyer, Johannes Czernin, Lutz Freudenberg, Frederik Giesel, Marcus Hacker, Rodney J. Hicks and Bernd J. Krause
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 47-53; DOI: https://doi.org/10.2967/jnumed.122.264298
- BRIEF COMMUNICATION
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    ¹⁷⁷Lu-PSMA for Extended Treatment of Metastatic Castration-Resistant Prostate Cancer
    Thorsten Derlin, Liam Widjaja, Rudolf A. Werner and Frank M. Bengel
    
    Journal of Nuclear Medicine January 1, 2023, 64 (1) 54-58; DOI: https://doi.org/10.2967/jnumed.122.264293
- BRIEF COMMUNICATION
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    Feasibility of ^99mTc-MIP-1404 for SPECT/CT Imaging and Subsequent PSMA-Radioguided Surgery in Early Biochemically Recurrent Prostate Cancer: A Case Series of 9 Patients
    Daniel Koehler, Markus Sauer, Susanne Klutmann, Ivayla Apostolova, Wencke Lehnert, Lars Budäus, Sophie Knipper and Tobias Maurer
    
    Journal of Nuclear Medicine January 1, 2023, 64 (1) 59-62; DOI: https://doi.org/10.2967/jnumed.122.263892
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  The Impact of Peptide Amount on Tumor Uptake to Assess PSMA Receptor Saturation on ⁶⁸Ga-PSMA-11 PET/CT in Patients with Primary Prostate Cancer
  Hinke Siebinga, Judith olde Heuvel, Erik-Jan Rijkhorst, Jeroen J.M.A. Hendrikx and Berlinda J. de Wit-van der Veen
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 63-68; DOI: https://doi.org/10.2967/jnumed.122.264101
Basic
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  The Prognostic Value of Posttreatment ⁶⁸Ga-PSMA-11 PET/CT and ¹⁸F-FDG PET/CT in Metastatic Castration-Resistant Prostate Cancer Treated with ¹⁷⁷Lu-PSMA-617 and NOX66 in a Phase I/II Trial (LuPIN)
  Sarennya Pathmanandavel, Megan Crumbaker, Andrew Nguyen, Andrew O. Yam, Peter Wilson, Remy Niman, Maria Ayers, Shikha Sharma, Peter Eu, Andrew J. Martin, Martin R. Stockler, Anthony M. Joshua and Louise Emmett
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 69-74; DOI: https://doi.org/10.2967/jnumed.122.264104

Oncology

Clinical
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  Lack of Adherence to Guideline-Based Imaging Before Subsequent Radiation in Patients with Non–Small Cell Lung Cancer: Impact on Patient Outcomes
  Emily Sterbis, Rifei Liang, Premal Trivedi, Jennifer Kwak, Erica Cohen Major, Sana D. Karam and Rustain L. Morgan
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 75-81; DOI: https://doi.org/10.2967/jnumed.122.264131
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  Intraoperative Molecular Fluorescence Imaging of Pancreatic Cancer by Targeting Vascular Endothelial Growth Factor: A Multicenter Feasibility Dose-Escalation Study
  Babs G. Sibinga Mulder, Marjory Koller, Evelien W. Duiker, Arantza Farina Sarasqueta, Jakobus Burggraaf, Vincent E. de Meijer, Alexander L. Vahrmeijer, Frederik J.H. Hoogwater, Bert A. Bonsing, Gooitzen M. van Dam, J. Sven D. Mieog and Bobby K. Pranger
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 82-89; DOI: https://doi.org/10.2967/jnumed.121.263773
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  Diagnostic Accuracy of ^99mTc-Sestamibi SPECT/CT for Characterization of Solid Renal Masses
  Ashwin Singh Parihar, Joyce Mhlanga, Carrie Ronstrom, Lisa R. Schmidt, Robert S. Figenshau, Farrokh Dehdashti and Richard L. Wahl
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 90-95; DOI: https://doi.org/10.2967/jnumed.122.264329
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  Optimized Whole-Body PET MRI Sequence Workflow in Pediatric Hodgkin Lymphoma Patients
  Thomas W. Georgi, Dietrich Stoevesandt, Lars Kurch, Jörg M. Bartelt, Dirk Hasenclever, Helmut Dittmann, Jiri Ferda, Peter Francis, Christiane Franzius, Christian Furth, Daniel Gräfe, Alexander Gussew, Martin Hüllner, Leon J. Menezes, Mona Mustafa, Lars Stegger, Lale Umutlu, Klaus Zöphel, Pietro Zucchetta, Dieter Körholz, Osama Sabri, Christine Mauz-Körholz and Regine Kluge
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 96-101; DOI: https://doi.org/10.2967/jnumed.122.264112
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  Application of the Lugano Classification for Initial Evaluation, Staging, and Response Assessment of Hodgkin and Non-Hodgkin Lymphoma: The PRoLoG Consensus Initiative (Part 1—Clinical)
  Fabien Ricard, Bruce Cheson, Sally Barrington, Judith Trotman, Annette Schmid, Guenther Brueggenwerth, Gilles Salles, Larry Schwartz, Greg Goldmacher, Rudresh Jarecha, Jayant Narang, Florence Broussais, Paul Galette, Min Liu, Surabhi Bajpai, Eric Perlman, Julie Gillis, Ira Smalberg, Pierre Terve, Gudrun Zahlmann and Ron Korn
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 102-108; DOI: https://doi.org/10.2967/jnumed.122.264106
Basic
- Open Access
  Cure of Micrometastatic B-Cell Lymphoma in a SCID Mouse Model Using ²¹³Bi-Anti-CD20 Monoclonal Antibody
  Gregory T. Havlena, Nirav S. Kapadia, Peng Huang, Hong Song, James Engles, Martin Brechbiel, George Sgouros and Richard L. Wahl
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 109-116; DOI: https://doi.org/10.2967/jnumed.122.263962
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  ¹⁸F-FDG PET Visualizes Systemic STING Agonist-Induced Lymphocyte Activation in Preclinical Models
  Thuc M. Le, Hailey R. Lee, Evan R. Abt, Khalid Rashid, Amanda L. Creech, Keke Liang, Jing Cui, Arthur Cho, Liu Wei, Amanda Labora, Charlotte Chan, Eric Sanchez, Kriti Kriti, Daniel Karin, Luyi Li, Nanping Wu, Christine Mona, Giuseppe Carlucci, Willy Hugo, Ting-Ting Wu, Timothy R. Donahue, Johannes Czernin and Caius G. Radu
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 117-123; DOI: https://doi.org/10.2967/jnumed.122.264121
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  Effective Treatment of Human Breast Carcinoma Xenografts with Single-Dose ²¹¹At-Labeled Anti-HER2 Single-Domain Antibody Fragment
  Yutian Feng, Rebecca Meshaw, Xiao-Guang Zhao, Stephen Jannetti, Ganesan Vaidyanathan and Michael R. Zalutsky
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 124-130; DOI: https://doi.org/10.2967/jnumed.122.264071
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  ¹⁸F-Fluciclovine PET Imaging of Glutaminase Inhibition in Breast Cancer Models
  Rong Zhou, Hoon Choi, Jianbo Cao, Austin Pantel, Mamta Gupta, Hsiaoju S. Lee and David Mankoff
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 131-136; DOI: https://doi.org/10.2967/jnumed.122.264152
- FEATURED BASIC SCIENCE ARTICLE
  - Open Access
    Antigen-Dependent Inducible T-Cell Reporter System for PET Imaging of Breast Cancer and Glioblastoma
    Jaehoon Shin, Matthew F.L. Parker, Iowis Zhu, Aryn Alanizi, Carlos I. Rodriguez, Raymond Liu, Payal B. Watchmaker, Mausam Kalita, Joseph Blecha, Justin Luu, Brian Wright, Suzanne E. Lapi, Robert R. Flavell, Hideho Okada, Thea D. Tlsty, Kole T. Roybal and David M. Wilson
    
    Journal of Nuclear Medicine January 1, 2023, 64 (1) 137-144; DOI: https://doi.org/10.2967/jnumed.122.264284

Covid Commentaries

Clinical
- BRIEF COMMUNICATION
  - Open Access
    In Vivo Visualization and Quantification of Neutrophil Elastase in Lungs of COVID-19 Patients: A First-in-Humans PET Study with ¹¹C-NES
    Gunnar Antoni, Mark Lubberink, Jens Sörensen, Elin Lindström, Mathias Elgland, Olof Eriksson, Michael Hultström, Robert Frithiof, Anders Wanhainen, Jonathan Sigfridsson, Paul Skorup and Miklos Lipcsey
    
    Journal of Nuclear Medicine January 1, 2023, 64 (1) 145-148; DOI: https://doi.org/10.2967/jnumed.122.263974

Cardiovascular

Clinical
- SPECIAL CONTRIBUTION
  - Open Access
    SNMMI/ACR/ASNC/SCMR Joint Credentialing Statement for Cardiac PET/MRI: Endorsed by the American Heart Association
    Terrence D. Ruddy, Mouaz Al-Mallah, James A. Arrighi, John P. Bois, David A. Bluemke, Marcelo F. Di Carli, Vasken Dilsizian, Robert J. Gropler, Hossein Jadvar, Saurabh Malhotra, Matthieu Pelletier-Galarneau, Thomas H. Schindler, Pamela K. Woodard and Panithaya Chareonthaitawee
    
    Journal of Nuclear Medicine January 1, 2023, 64 (1) 149-152; DOI: https://doi.org/10.2967/jnumed.122.264200

Neurology

Clinical
- Open Access
  High-Resolution Silicon Photomultiplier Time-of-Flight Dedicated Head PET System for Clinical Brain Studies
  Kazunari Ishii, Kohei Hanaoka, Shota Watanabe, Daisuke Morimoto-Ishikawa, Takahiro Yamada, Hayato Kaida, Yoshiyuki Yamakawa, Suzuka Minagawa, Shiho Takenouchi, Atsushi Ohtani and Tetsuro Mizuta
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 153-158; DOI: https://doi.org/10.2967/jnumed.122.264080

Inflammation/Infection

Clinical
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  Whole-Body PET Imaging in Humans Shows That ¹¹C-PS13 Is Selective for Cyclooxygenase-1 and Can Measure the In Vivo Potency of Nonsteroidal Antiinflammatory Drugs
  Min-Jeong Kim, Fernanda Juarez Anaya, Lester S. Manly, Jae-Hoon Lee, Jinsoo Hong, Stal Shrestha, Sanjay Telu, Katharine Henry, Jose A. Montero Santamaria, Jeih-San Liow, Paolo Zanotti-Fregonara, H. Umesha Shetty, Sami S. Zoghbi, Victor W. Pike and Robert B. Innis
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 159-164; DOI: https://doi.org/10.2967/jnumed.122.264061

Radiobiology/Dosimetry

Clinical
- Open Access
  Estimating the Risk for Secondary Cancer After Targeted α-Therapy with ²¹¹At Intraperitoneal Radioimmunotherapy
  Erik Leidermark, Andreas Hallqvist, Lars Jacobsson, Per Karlsson, Erik Holmberg, Tom Bäck, Mia Johansson, Sture Lindegren, Stig Palm and Per Albertsson
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 165-172; DOI: https://doi.org/10.2967/jnumed.121.263349

Radiochemsitry/Radiopharmaceuticals

Basic
- BRIEF COMMUNICATION
  - Open Access
    An Experimental Generator for Production of High-Purity ²¹²Pb for Use in Radiopharmaceuticals
    Ruth Gong Li, Vilde Yuli Stenberg and Roy Hartvig Larsen
    
    Journal of Nuclear Medicine January 1, 2023, 64 (1) 173-176; DOI: https://doi.org/10.2967/jnumed.122.264009

Molecular Imaging

Basic
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  Detection of Shortwave-Infrared Cerenkov Luminescence from Medical Isotopes
  Benedict E. Mc Larney, Qize Zhang, Edwin C. Pratt, Magdalena Skubal, Elizabeth Isaac, Hsiao-Ting Hsu, Anuja Ogirala and Jan Grimm
  
  Journal of Nuclear Medicine January 1, 2023, 64 (1) 177-182; DOI: https://doi.org/10.2967/jnumed.122.264079

Letters To The Editor

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What Does an Imaging “Selection” Claim Actually Mean?
Rafel Dwaine Rieves

Journal of Nuclear Medicine January 1, 2023, 64 (1) 183; DOI: https://doi.org/10.2967/jnumed.122.264567
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Reply: What Does an Imaging “Selection” Claim Actually Mean?
Phillip H. Kuo

Journal of Nuclear Medicine January 1, 2023, 64 (1) 183-184; DOI: https://doi.org/10.2967/jnumed.122.264835

Departments

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Recruitment
Journal of Nuclear Medicine January 1, 2023, 64 (1) 2A;