Article Figures & Data
Figures
- FIGURE 1.
View of 3 tomographic sections of rod-shaped cluster of cells with cold region in interior. Red cells are labeled with radionuclide. Green cells are unlabeled. Opaque cells are alive, and translucent cells are dead. Blue lines point to tomographic section of corresponding cell layer.
- FIGURE 2.
“Source Radiation” tab.
- FIGURE 3.
“Cell Source/Target” tab.
- FIGURE 4.
Complex radiobiologic parameters.
- FIGURE 6.
Tomographic section through center of spherical cell cluster illustrating drug penetration depth, labeled cells (red), unlabeled cells (green), alive cells (opaque), and dead cells (translucent). Only unlabeled cells at center of cluster are alive.
- FIGURE 5.
“Multicellular Geometry” tab. SF variation as function of mean activity per cell is shown on right.
- FIGURE 7.
Comparison of MIRDcell prediction with experimental observations. Original plots extracted from Kennel et al. (21) have been overlayed with MIRDcell predictions (red). (A) EMT-6 cells. (B) LINE-1 cells. Triangles are data obtained for MAb13A, and circles are those obtained for MAb14, which is nonbinding with tissue. Solid lines are least-squares fits to exponential function provided by Kennel et al. MIRDcell simulation was run for MAb13A cells.
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