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Research ArticleBasic Science Investigation

Ferronostics: Measuring Tumoral Ferrous Iron with PET to Predict Sensitivity to Iron-Targeted Cancer Therapies

Ning Zhao, Yangjie Huang, Yung-hua Wang, Ryan K. Muir, Ying-Chu Chen, Junnian Wei, Nima Hooshdaran, Pavithra Viswanath, Youngho Seo, Davide Ruggero, Adam R. Renslo and Michael J. Evans
Journal of Nuclear Medicine July 2021, 62 (7) 949-955; DOI: https://doi.org/10.2967/jnumed.120.252460
Ning Zhao
1Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California;
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Yangjie Huang
1Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California;
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Yung-hua Wang
1Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California;
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Ryan K. Muir
2Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California;
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Ying-Chu Chen
2Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California;
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Junnian Wei
1Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California;
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Nima Hooshdaran
1Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California;
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Pavithra Viswanath
1Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California;
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Youngho Seo
1Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California;
3Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California; and
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Davide Ruggero
3Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California; and
4Department of Urology, University of California, San Francisco, San Francisco, California
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Adam R. Renslo
2Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California;
3Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California; and
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Michael J. Evans
1Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California;
2Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California;
3Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California; and
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Article Information

vol. 62 no. 7 949-955
DOI 
https://doi.org/10.2967/jnumed.120.252460
PubMed 
33246980

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication June 25, 2020
  • Accepted for publication November 5, 2020
  • Published online July 9, 2021.

Article Versions

  • previous version (November 27, 2020 - 13:56).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2021 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Ning Zhao1,
  2. Yangjie Huang1,
  3. Yung-hua Wang1,
  4. Ryan K. Muir2,
  5. Ying-Chu Chen2,
  6. Junnian Wei1,
  7. Nima Hooshdaran1,
  8. Pavithra Viswanath1,
  9. Youngho Seo1,3,
  10. Davide Ruggero3,4,
  11. Adam R. Renslo*2,3 and
  12. Michael J. Evans*1–3
  1. 1Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California;
  2. 2Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California;
  3. 3Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California; and
  4. 4Department of Urology, University of California, San Francisco, San Francisco, California
  1. For correspondence or reprints contact: Michael J. Evans, University of California, San Francisco, 600 16th S., N572C, San Francisco, CA 94158. E-mail: michael.evans{at}ucsf.edu
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Journal of Nuclear Medicine: 62 (7)
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Ferronostics: Measuring Tumoral Ferrous Iron with PET to Predict Sensitivity to Iron-Targeted Cancer Therapies
Ning Zhao, Yangjie Huang, Yung-hua Wang, Ryan K. Muir, Ying-Chu Chen, Junnian Wei, Nima Hooshdaran, Pavithra Viswanath, Youngho Seo, Davide Ruggero, Adam R. Renslo, Michael J. Evans
Journal of Nuclear Medicine Jul 2021, 62 (7) 949-955; DOI: 10.2967/jnumed.120.252460

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Ferronostics: Measuring Tumoral Ferrous Iron with PET to Predict Sensitivity to Iron-Targeted Cancer Therapies
Ning Zhao, Yangjie Huang, Yung-hua Wang, Ryan K. Muir, Ying-Chu Chen, Junnian Wei, Nima Hooshdaran, Pavithra Viswanath, Youngho Seo, Davide Ruggero, Adam R. Renslo, Michael J. Evans
Journal of Nuclear Medicine Jul 2021, 62 (7) 949-955; DOI: 10.2967/jnumed.120.252460
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