γ-Tocotrienol–Loaded Liposomes for Radioprotection from Hematopoietic Side Effects Caused by Radiotherapeutic Drugs

Sang-gyu Lee; Teja Muralidhar Kalidindi; Hanzhi Lou; Kishore Gangangari; Blesida Punzalan; Ariana Bitton; Casey J. Lee; Hebert A. Vargas; Soobin Park; Lisa Bodei; Michael G. Kharas; Vijay K. Singh; Naga Vara Kishore Pillarsetty; Steven M. Larson

doi:10.2967/jnumed.120.244681

Research ArticleRadiobiology/Dosimetry

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γ-Tocotrienol–Loaded Liposomes for Radioprotection from Hematopoietic Side Effects Caused by Radiotherapeutic Drugs

Sang-gyu Lee, Teja Muralidhar Kalidindi, Hanzhi Lou, Kishore Gangangari, Blesida Punzalan, Ariana Bitton, Casey J. Lee, Hebert A. Vargas, Soobin Park, Lisa Bodei, Michael G. Kharas, Vijay K. Singh, Naga Vara Kishore Pillarsetty and Steven M. Larson

Journal of Nuclear Medicine April 2021, 62 (4) 584-590; DOI: https://doi.org/10.2967/jnumed.120.244681

Sang-gyu Lee

1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York

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Teja Muralidhar Kalidindi

1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York

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Hanzhi Lou

2Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York

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Kishore Gangangari

1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York

3Department of Chemistry, Hunter College, City University of New York, New York, New York

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Blesida Punzalan

1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York

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Ariana Bitton

4New York University, New York, New York

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Casey J. Lee

4New York University, New York, New York

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Hebert A. Vargas

1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York

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Soobin Park

5Hunter College, New York, New York

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Lisa Bodei

1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York

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Michael G. Kharas

2Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York

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Vijay K. Singh

6Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland

7Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, Maryland; and

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Naga Vara Kishore Pillarsetty

1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York

8Department of Radiology, Weill Cornell Medical College, New York, New York

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Steven M. Larson

1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York

2Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York

8Department of Radiology, Weill Cornell Medical College, New York, New York

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γ-Tocotrienol–Loaded Liposomes for Radioprotection from Hematopoietic Side Effects Caused by Radiotherapeutic Drugs

Journal of Nuclear Medicine Apr 2021, 62 (4) 584-590; DOI: 10.2967/jnumed.120.244681

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γ-Tocotrienol–Loaded Liposomes for Radioprotection from Hematopoietic Side Effects Caused by Radiotherapeutic Drugs

Journal of Nuclear Medicine Apr 2021, 62 (4) 584-590; DOI: 10.2967/jnumed.120.244681

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Keywords

bone marrow
liposome
γ-tocotrienol
Radiation Protection

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