Applicationof compound iodine oral solution in 131I treatment of severe hyperthyroidism.

Objectives: To investigate the application value of compound iodine oral solution in the prevention of hyperthyroidism during 131I treatment of severe hyperthyroidism. Materials and Methods: Thirty-two patients with severe hyperthyroidism who were treated with 131I were randomly divided into experimental group G1 ( Compound iodine oral solution orally, 16 patients) and control group G0 (Methimazole tablets orally, 16 patients). The difference of serum free T3 (FT3) and free T4 (FT4) in the two groups after 131I treatment was compared one month later.

Results: There was no significant difference in the rate of change of serum FT3 and FT4 between the experimental group and the control group (P1=0.383; P2=0.231).

Conclusions: The effect of compound iodine oral solution on reducing thyroid hormone levels in 131I treatment of severe hyperthyroidism is equivalent to that of Methimazole tablets, but the side effects are smaller than Methimazole tablets, which plays an important role in preventing hyperthyroidism. Key words:compound iodine oral solution, severe hyperthyroidism, anti-thyroid drugs