Dose-Dependent Growth Delay of Breast Cancer Xenografts in the Bone Marrow of Mice Treated with 223Ra: The Role of Bystander Effects and Their Potential for Therapy

Calvin N. Leung; Brian S. Canter; Didier Rajon; Tom A. Bäck; J. Christopher Fritton; Edouard I. Azzam; Roger W. Howell

doi:10.2967/jnumed.119.227835

Research ArticleRadionuclide Therapy

Dose-Dependent Growth Delay of Breast Cancer Xenografts in the Bone Marrow of Mice Treated with ²²³Ra: The Role of Bystander Effects and Their Potential for Therapy

Calvin N. Leung, Brian S. Canter, Didier Rajon, Tom A. Bäck, J. Christopher Fritton, Edouard I. Azzam and Roger W. Howell

Journal of Nuclear Medicine January 2020, 61 (1) 89-95; DOI: https://doi.org/10.2967/jnumed.119.227835

Calvin N. Leung

1Department of Radiology, New Jersey Medical School, Rutgers University, Newark, New Jersey

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Brian S. Canter

1Department of Radiology, New Jersey Medical School, Rutgers University, Newark, New Jersey

2Department of Orthopedics, New Jersey Medical School, Rutgers University, Newark, New Jersey

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Didier Rajon

3Department of Neurosurgery, University of Florida, Gainesville, Florida; and

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Tom A. Bäck

4Department of Radiation Physics, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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J. Christopher Fritton

2Department of Orthopedics, New Jersey Medical School, Rutgers University, Newark, New Jersey

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Edouard I. Azzam

1Department of Radiology, New Jersey Medical School, Rutgers University, Newark, New Jersey

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Roger W. Howell

1Department of Radiology, New Jersey Medical School, Rutgers University, Newark, New Jersey

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Journal of Nuclear Medicine

Vol. 61, Issue 1

January 1, 2020

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Dose-Dependent Growth Delay of Breast Cancer Xenografts in the Bone Marrow of Mice Treated with ²²³Ra: The Role of Bystander Effects and Their Potential for Therapy

Calvin N. Leung, Brian S. Canter, Didier Rajon, Tom A. Bäck, J. Christopher Fritton, Edouard I. Azzam, Roger W. Howell

Journal of Nuclear Medicine Jan 2020, 61 (1) 89-95; DOI: 10.2967/jnumed.119.227835

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Dose-Dependent Growth Delay of Breast Cancer Xenografts in the Bone Marrow of Mice Treated with ²²³Ra: The Role of Bystander Effects and Their Potential for Therapy

Calvin N. Leung, Brian S. Canter, Didier Rajon, Tom A. Bäck, J. Christopher Fritton, Edouard I. Azzam, Roger W. Howell

Journal of Nuclear Medicine Jan 2020, 61 (1) 89-95; DOI: 10.2967/jnumed.119.227835

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Keywords

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bystander effect
breast cancer
223Ra

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Dose-Dependent Growth Delay of Breast Cancer Xenografts in the Bone Marrow of Mice Treated with ²²³Ra: The Role of Bystander Effects and Their Potential for Therapy

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