Simplified Methods for Quantification of 18F-DCFPyL Uptake in Patients with Prostate Cancer

Bernard H.E. Jansen; Maqsood Yaqub; Jens Voortman; Matthijs C.F. Cysouw; Albert D. Windhorst; Robert C. Schuit; Gerbrand M. Kramer; Alfons J.M. van den Eertwegh; Lothar A. Schwarte; N. Harry Hendrikse; André N. Vis; Reindert J.A. van Moorselaar; Otto S. Hoekstra; Ronald Boellaard; Daniela E. Oprea-Lager

doi:10.2967/jnumed.119.227520

Research ArticleTheranostics

Simplified Methods for Quantification of ¹⁸F-DCFPyL Uptake in Patients with Prostate Cancer

Bernard H.E. Jansen, Maqsood Yaqub, Jens Voortman, Matthijs C.F. Cysouw, Albert D. Windhorst, Robert C. Schuit, Gerbrand M. Kramer, Alfons J.M. van den Eertwegh, Lothar A. Schwarte, N. Harry Hendrikse, André N. Vis, Reindert J.A. van Moorselaar, Otto S. Hoekstra, Ronald Boellaard and Daniela E. Oprea-Lager

Journal of Nuclear Medicine December 2019, 60 (12) 1730-1735; DOI: https://doi.org/10.2967/jnumed.119.227520

Bernard H.E. Jansen

1Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands

2Department of Urology, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands

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Maqsood Yaqub

1Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands

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Jens Voortman

3Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands

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Matthijs C.F. Cysouw

1Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands

3Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands

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Albert D. Windhorst

1Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands

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Robert C. Schuit

1Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands

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Gerbrand M. Kramer

1Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands

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Alfons J.M. van den Eertwegh

3Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands

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Lothar A. Schwarte

4Department of Anesthesiology, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands; and

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N. Harry Hendrikse

1Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands

4Department of Anesthesiology, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands; and

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André N. Vis

3Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands

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Reindert J.A. van Moorselaar

2Department of Urology, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands

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Otto S. Hoekstra

1Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands

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Ronald Boellaard

1Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands

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Daniela E. Oprea-Lager

1Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam University Medical Centers (location VU University Medical Center), Amsterdam, The Netherlands

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Simplified Methods for Quantification of ¹⁸F-DCFPyL Uptake in Patients with Prostate Cancer

Journal of Nuclear Medicine Dec 2019, 60 (12) 1730-1735; DOI: 10.2967/jnumed.119.227520

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Simplified Methods for Quantification of ¹⁸F-DCFPyL Uptake in Patients with Prostate Cancer

Journal of Nuclear Medicine Dec 2019, 60 (12) 1730-1735; DOI: 10.2967/jnumed.119.227520

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Keywords

prostate cancer
18F-DCFPyL
PSMA
pharmacokinetics
quantification

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