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Journal of Nuclear Medicine

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Table of Contents

December 1, 2019; Volume 60,Issue 12

This Month in JNM

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    This Month in JNM
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 6A;

Editor’s Page

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    Of Sheep and Wolves: Curtailing Coverage for Essential Imaging Tests Based on Flawed Use and Cost Arguments
    Johannes Czernin, Martin Allen-Auerbach and Jeremie Calais
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 1657-1658; DOI: https://doi.org/10.2967/jnumed.119.237636

Discussions with Leaders

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    A Conversation Between Stefano Buono and Ken Herrmann
    Stefano Buono and Ken Herrmann
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 1659-1662; DOI: https://doi.org/10.2967/jnumed.119.238212

Hot Topics

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    The Path to the Future: Education of Nuclear Medicine Therapeutic Specialists as Responsible Physicians
    Lisa Bodei, Arturo Chiti, Irvin M. Modlin, Andrew M. Scott and Heiko Schöder
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 1663-1664; DOI: https://doi.org/10.2967/jnumed.119.232454

The State of The Art

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    Molecular Imaging with Reporter Genes: Has Its Promise Been Delivered?
    Inna Serganova and Ronald G. Blasberg
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 1665-1681; DOI: https://doi.org/10.2967/jnumed.118.220004

Continuing Education

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    Long-Term Clinical and Neuronuclear Imaging Sequelae of Cancer Therapy, Trauma, and Brain Injury
    April Alcantara, Gholam R. Berenji, Carole S. Scherling, Beata Durcanova, Daniel Diaz-Aguilar and Daniel H.S. Silverman
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 1682-1690; DOI: https://doi.org/10.2967/jnumed.119.237578

Focus on Molecular Imaging

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    Targeting P-Selectin Adhesion Molecule in Molecular Imaging: P-Selectin Expression as a Valuable Imaging Biomarker of Inflammation in Cardiovascular Disease
    Lydia A. Perkins, Carolyn J. Anderson and Enrico M. Novelli
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 1691-1697; DOI: https://doi.org/10.2967/jnumed.118.225169

Oncology

  • Clinical

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      Prospective Evaluation of a Tumor Control Probability Model Based on Dynamic 18F-FMISO PET for Head and Neck Cancer Radiotherapy
      Daniela Thorwarth, Stefan Welz, David Mönnich, Christina Pfannenberg, Konstantin Nikolaou, Matthias Reimold, Christian La Fougère, Gerald Reischl, Paul-Stefan Mauz, Frank Paulsen, Markus Alber, Claus Belka and Daniel Zips
      Journal of Nuclear Medicine December 1, 2019, 60 (12) 1698-1704; DOI: https://doi.org/10.2967/jnumed.119.227744
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      18F-Choline PET/mpMRI for Detection of Clinically Significant Prostate Cancer: Part 2. Cost-Effectiveness Analysis
      Christine L. Barnett, Matthew S. Davenport, Jeffrey S. Montgomery, Lakshmi Priya Kunju, Brian T. Denton and Morand Piert
      Journal of Nuclear Medicine December 1, 2019, 60 (12) 1705-1712; DOI: https://doi.org/10.2967/jnumed.119.225771
    • BRIEF COMMUNICATION

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        No Added Value of 18F-Sodium Fluoride PET/CT for the Detection of Bone Metastases in Patients with Newly Diagnosed Prostate Cancer with Normal Bone Scintigraphy
        Helle D. Zacho, Mads R. Jochumsen, Niels C. Langkilde, Jesper C. Mortensen, Christian Haarmark, Helle W. Hendel, Jørgen B. Jensen and Lars J. Petersen
        Journal of Nuclear Medicine December 1, 2019, 60 (12) 1713-1716; DOI: https://doi.org/10.2967/jnumed.119.229062

Theranostics

  • Clinical

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      A Prospective Observational Study to Evaluate the Effects of Long-Acting Somatostatin Analogs on 68Ga-DOTATATE Uptake in Patients with Neuroendocrine Tumors
      Anni Gålne, Helen Almquist, Martin Almquist, Cecilia Hindorf, Tomas Ohlsson, Erik Nordenström, Anna Sundlöv and Elin Trägårdh
      Journal of Nuclear Medicine December 1, 2019, 60 (12) 1717-1723; DOI: https://doi.org/10.2967/jnumed.119.226332
    • FEATURED CLINICAL INVESTIGATION ARTICLE

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        68Ga-Pentixafor PET/CT for Imaging of Chemokine Receptor 4 Expression in Waldenström Macroglobulinemia/Lymphoplasmacytic Lymphoma: Comparison to 18F-FDG PET/CT
        Yaping Luo, Xinxin Cao, Qingqing Pan, Jian Li, Jun Feng and Fang Li
        Journal of Nuclear Medicine December 1, 2019, 60 (12) 1724-1729; DOI: https://doi.org/10.2967/jnumed.119.226134
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      Simplified Methods for Quantification of 18F-DCFPyL Uptake in Patients with Prostate Cancer
      Bernard H.E. Jansen, Maqsood Yaqub, Jens Voortman, Matthijs C.F. Cysouw, Albert D. Windhorst, Robert C. Schuit, Gerbrand M. Kramer, Alfons J.M. van den Eertwegh, Lothar A. Schwarte, N. Harry Hendrikse, André N. Vis, Reindert J.A. van Moorselaar, Otto S. Hoekstra, Ronald Boellaard and Daniela E. Oprea-Lager
      Journal of Nuclear Medicine December 1, 2019, 60 (12) 1730-1735; DOI: https://doi.org/10.2967/jnumed.119.227520
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      Radiation Dosimetry and Biodistribution of 18F-PSMA-11 for PET Imaging of Prostate Cancer
      Sarah Piron, Kathia De Man, Nick Van Laeken, Yves D’Asseler, Klaus Bacher, Ken Kersemans, Piet Ost, Karel Decaestecker, Pieter Deseyne, Valérie Fonteyne, Nicolaas Lumen, Eric Achten, Boudewijn Brans and Filip De Vos
      Journal of Nuclear Medicine December 1, 2019, 60 (12) 1736-1742; DOI: https://doi.org/10.2967/jnumed.118.225250

Cardiology

  • Basic

    • FEATURED ARTICLE OF THE MONTH

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        Molecular Imaging of Fibroblast Activity After Myocardial Infarction Using a 68Ga-Labeled Fibroblast Activation Protein Inhibitor, FAPI-04
        Zohreh Varasteh, Sarajo Mohanta, Stephanie Robu, Miriam Braeuer, Yuanfang Li, Negar Omidvari, Geoffrey Topping, Ting Sun, Stephan G. Nekolla, Antonia Richter, Christian Weber, Andreas Habenicht, Uwe A. Haberkorn and Wolfgang A. Weber
        Journal of Nuclear Medicine December 1, 2019, 60 (12) 1743-1749; DOI: https://doi.org/10.2967/jnumed.119.226993
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      Imaging of Chemotherapy-Induced Acute Cardiotoxicity with 18F-Labeled Lipophilic Cations
      Stuart P. McCluskey, Anna Haslop, Christopher Coello, Roger N. Gunn, Edward W. Tate, Richard Southworth, Christophe Plisson, Nicholas J. Long and Lisa A. Wells
      Journal of Nuclear Medicine December 1, 2019, 60 (12) 1750-1756; DOI: https://doi.org/10.2967/jnumed.119.226787

Neurology

  • Clinical

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      Presynaptic Striatal Dopaminergic Function in Atypical Parkinsonism: A Metaanalysis of Imaging Studies
      Valtteri Kaasinen, Tuomas Kankare, Juho Joutsa and Tero Vahlberg
      Journal of Nuclear Medicine December 1, 2019, 60 (12) 1757-1763; DOI: https://doi.org/10.2967/jnumed.119.227140
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      Limits for Reduction of Acquisition Time and Administered Activity in 18F-FDG PET Studies of Alzheimer Dementia and Frontotemporal Dementia
      Florian Schiller, Lars Frings, Johannes Thurow, Philipp T. Meyer and Michael Mix
      Journal of Nuclear Medicine December 1, 2019, 60 (12) 1764-1770; DOI: https://doi.org/10.2967/jnumed.119.227132
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      A Fully Automatic Technique for Precise Localization and Quantification of Amyloid-β PET Scans
      Mouna Tahmi, Wassim Bou-Zeid and Qolamreza R. Razlighi
      Journal of Nuclear Medicine December 1, 2019, 60 (12) 1771-1779; DOI: https://doi.org/10.2967/jnumed.119.228510
  • Basic

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      In Vivo Synaptic Density Imaging with 11C-UCB-J Detects Treatment Effects of Saracatinib in a Mouse Model of Alzheimer Disease
      Takuya Toyonaga, Levi M. Smith, Sjoerd J. Finnema, Jean-Dominique Gallezot, Mika Naganawa, Jason Bini, Tim Mulnix, Zhengxin Cai, Jim Ropchan, Yiyun Huang, Stephen M. Strittmatter and Richard E. Carson
      Journal of Nuclear Medicine December 1, 2019, 60 (12) 1780-1786; DOI: https://doi.org/10.2967/jnumed.118.223867
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      Longitudinal PET Monitoring of Amyloidosis and Microglial Activation in a Second-Generation Amyloid-β Mouse Model
      Christian Sacher, Tanja Blume, Leonie Beyer, Finn Peters, Florian Eckenweber, Carmelo Sgobio, Maximilian Deussing, Nathalie L. Albert, Marcus Unterrainer, Simon Lindner, Franz-Josef Gildehaus, Barbara von Ungern-Sternberg, Irena Brzak, Ulf Neumann, Takashi Saito, Takaomi C. Saido, Peter Bartenstein, Axel Rominger, Jochen Herms and Matthias Brendel
      Journal of Nuclear Medicine December 1, 2019, 60 (12) 1787-1793; DOI: https://doi.org/10.2967/jnumed.119.227322

Radiobiology/Dosimetry

  • Clinical

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      Biodistribution and Dosimetry of Intraventricularly Administered 124I-Omburtamab in Patients with Metastatic Leptomeningeal Tumors
      Neeta Pandit-Taskar, Pat B. Zanzonico, Kim Kramer, Milan Grkovski, Edward K. Fung, Weiji Shi, Zhigang Zhang, Serge K. Lyashchenko, Alex M. Fung, Keith S. Pentlow, Jorge A. Carrasquillo, Jason S. Lewis, Steven M. Larson, Nai-Kong V. Cheung and John L. Humm
      Journal of Nuclear Medicine December 1, 2019, 60 (12) 1794-1801; DOI: https://doi.org/10.2967/jnumed.118.219576
  • Basic

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      PARaDIM: A PHITS-Based Monte Carlo Tool for Internal Dosimetry with Tetrahedral Mesh Computational Phantoms
      Lukas M. Carter, Troy M. Crawford, Tatsuhiko Sato, Takuya Furuta, Chansoo Choi, Chan Hyeong Kim, Justin L. Brown, Wesley E. Bolch, Pat B. Zanzonico and Jason S. Lewis
      Journal of Nuclear Medicine December 1, 2019, 60 (12) 1802-1811; DOI: https://doi.org/10.2967/jnumed.119.229013

Molecular Imaging

  • Basic

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      The Characterization of 18F-hGTS13 for Molecular Imaging of xC− Transporter Activity with PET
      Corinne Beinat, Gayatri Gowrishankar, Bin Shen, Israt S. Alam, Elise Robinson, Tom Haywood, Chirag B. Patel, Emily Carmen Azevedo, Jessa B. Castillo, Ohad Ilovich, Norman Koglin, Heribert Schmitt-Willich, Mathias Berndt, Andre Mueller, Marion Zerna, Ananth Srinivasan and Sanjiv Sam Gambhir
      Journal of Nuclear Medicine December 1, 2019, 60 (12) 1812-1817; DOI: https://doi.org/10.2967/jnumed.119.225870

Physics And Instrumentation

  • Basic

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      Performance Evaluation of a High-Resolution Nonhuman Primate PET/CT System
      Zsolt Sarnyai, Kálmán Nagy, Gergely Patay, Milán Molnár, Göran Rosenqvist, Miklós Tóth, Akihiro Takano, Balázs Gulyás, Péter Major, Christer Halldin and Andrea Varrone
      Journal of Nuclear Medicine December 1, 2019, 60 (12) 1818-1824; DOI: https://doi.org/10.2967/jnumed.117.206243
  • Translational

    • FEATURED TRANSLATIONAL SCIENCE ARTICLE

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        89Zr-Immuno-PET: Toward a Noninvasive Clinical Tool to Measure Target Engagement of Therapeutic Antibodies In Vivo
        Yvonne W.S. Jauw, Joseph A. O’Donoghue, Josée M. Zijlstra, Otto S. Hoekstra, C. Willemien Menke-van der Houven van Oordt, Franck Morschhauser, Jorge A. Carrasquillo, Sonja Zweegman, Neeta Pandit-Taskar, Adriaan A. Lammertsma, Guus. A.M.S. van Dongen, Ronald Boellaard, Wolfgang A. Weber and Marc C. Huisman
        Journal of Nuclear Medicine December 1, 2019, 60 (12) 1825-1832; DOI: https://doi.org/10.2967/jnumed.118.224568

Book Reviews

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    Radiopharmaceutical Chemistry
    Jae Min Jeong
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 1833; DOI: https://doi.org/10.2967/jnumed.119.237479

Letters to the Editor

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    Quantification of 18F‐DCFPyL Uptake: TBR Versus Patlak’s Analysis
    Eric Laffon, Henri de Clermont and Roger Marthan
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 1834; DOI: https://doi.org/10.2967/jnumed.119.232926
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    Reply: Quantification of 18F-DCFPyL Uptake: TBR Versus Patlak’s Analysis
    Bernard H.E. Jansen, Maqsood Yaqub, Matthijs C.F. Cysouw, André N. Vis, Reindert J.A. van Moorselaar, N. Harry Hendrikse, Otto S. Hoekstra, Ronald Boellaard and Daniela E. Oprea-Lager
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 1834-1835; DOI: https://doi.org/10.2967/jnumed.119.234047
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    Off-Target Report on 18F-Sodium Fluoride PET/CT for Detection of Skeletal Metastases in Prostate Cancer
    Poul F. Høilund-Carlsen and Abass Alavi
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 1835-1836; DOI: https://doi.org/10.2967/jnumed.119.232348
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    Reply: Off-Target Report on 18F-Sodium Fluoride PET/CT for Detection of Skeletal Metastases in Prostate Cancer
    Helle Damgaard Zacho and Lars J. Petersen
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 1836; DOI: https://doi.org/10.2967/jnumed.119.234146

SNMMI Newsline

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    SNMMI Newsline
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 7N-18N;
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    2019 SNMMI Highlights Lecture: Cardiovascular Nuclear and Molecular Imaging
    Mehran M. Sadeghi
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 7N-13N;
  • You have access
    Grants, Awards, Scholarships Now Open for Application
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 13N;
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    NRC Advisory Committee on Medical Uses of Isotopes Fall Meeting
    Caitlin Kubler
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 14N;
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    Perseverating on Epidemiology and Linearity: A Journey into the Minds of LNT Model Advocates
    Jeffry A. Siegel, Bill Sacks, Charles W. Pennington and Bennett S. Greenspan
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 15N-16N;
  • You have access
    SNMMI Leadership Update: The State of SNMMI: Financially Strong and Positioned for Growth
    Virginia Pappas
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 17N;
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    From the Literature
    Journal of Nuclear Medicine December 1, 2019, 60 (12) 18N;
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In this issue

Journal of Nuclear Medicine: 60 (12)
Journal of Nuclear Medicine
Vol. 60, Issue 12
December 1, 2019
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author

Issue highlights

  • Molecular Imaging of Fibroblast Activity After Myocardial Infarction Using a 68Ga-Labeled Fibroblast Activation Protein Inhibitor, FAPI-04
  • 68Ga-Pentixafor PET/CT for Imaging of Chemokine Receptor 4 Expression in Waldenström Macroglobulinemia/Lymphoplasmacytic Lymphoma: Comparison to 18F-FDG PET/CT
  • 89Zr-Immuno-PET: Toward a Noninvasive Clinical Tool to Measure Target Engagement of Therapeutic Antibodies In Vivo
  • Molecular Imaging with Reporter Genes: Has Its Promise Been Delivered?
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    • Clinical
      • BRIEF COMMUNICATION
  • Theranostics
    • Clinical
      • FEATURED CLINICAL INVESTIGATION ARTICLE
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    • Basic
      • FEATURED ARTICLE OF THE MONTH
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  • Initial Clinical Experience with 90Y-FAPI-46 Radioligand Therapy for Advanced-Stage Solid Tumors: A Case Series of 9 Patients
  • Total-Body PET Multiparametric Imaging of Cancer Using a Voxelwise Strategy of Compartmental Modeling
  • Prospective phase 2 trial of PSMA-targeted molecular RadiothErapy with 177Lu-PSMA-617 for metastatic castration-reSISTant Prostate Cancer (RESIST-PC): efficacy results of the UCLA cohort
  • Why We Did What We Did: PSMA PET/CT Selection Criteria for the VISION Trial
  • 68Ga-FAPI as a Diagnostic Tool in Sarcoma: Data from the 68Ga-FAPI PET Prospective Observational Trial
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