Article Figures & Data
Figures
- FIGURE 1.
Representative 68Ga-NOTA-UBI PET/CT biodistribution in NHPs 60 min after tracer administration (189 MBq).
- FIGURE 2.
68Ga-NOTA-UBI PET maximum-intensity projection (skull to midthigh) demonstrating physiologic tracer biodistribution in healthy male (A) and female (B) volunteers. Images were acquired 60 min after intravenous injection of 129 and 132 MBq, respectively, of tracer.
- FIGURE 3.
68Ga-NOTA-UBI PET/CT images in representative patient with peripheral bone- and soft-tissue infection. (A) Whole-body maximum-intensity projection shows diffusely increased tracer uptake in right lower leg. (B) Detailed images demonstrate focal increased tracer uptake in ankle joint extending to adjacent bone (black and white arrows), as well as diffuse tracer uptake in calf muscles (red arrows); no significant uptake in contralateral leg was noted. Images were obtained 60 min after tracer administration (240 MBq).
- FIGURE 4.
Representative MR and 68Ga-NOTA-UBI PET/CT images in patient with suspected spinal infection (spondylodiskitis). (A–C) Coronal T1-weighted MR image (fat suppression) (A), whole-body maximum-intensity-projection PET image (B), and sequential transaxial fused PET/CT (top), PET (middle), and CT (bottom) images (C) showing focally increased uptake (arrowheads) in intervertebral region of L3–L4 corresponding to abnormal findings on MRI. K = kidney.
Tables
Organ Dose (μSv/MBq) %CV Adrenals 6.21 5.0 Brain 1.16 9.5 Breast 4.95 7.4 Gallbladder wall 6.84 5.5 Lower left intestine 8.50 15.5 Small intestine 7.58 7.0 Stomach wall 6.56 2.4 Upper left intestine 7.28 6.9 Heart wall 10.00 6.8 Kidneys 23.10 19.0 Liver 17.70 27.9 Lung 11.70 13.3 Muscle 3.70 9.7 Ovaries 7.60 10.0 Pancreas 6.15 21.0 Red marrow 6.67 5.6 Osteogenic cells 9.64 5.8 Skin 4.59 5.2 Spleen 7.67 15.5 Testes 5.01 25.6 Thymus 5.35 6.7 Thyroid 3.55 4.5 Urinary bladder wall 185.00 58.6 Uterus 10.30 22.2 Total body 6.84 0.6 %CV = coefficient of variance (%).
Supplemental Data
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