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Journal of Nuclear Medicine

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About the Cover

February 1, 2018; Volume 59,Issue 2

This Month in JNM

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    This Month in JNM
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 8A;

Hot Topics

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    Selective Tau Imaging: Der Stand der Dinge
    Victor L. Villemagne
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 175-176; DOI: https://doi.org/10.2967/jnumed.117.198325

The State of the Art

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    Why Targeting PSMA Is a Game Changer in the Management of Prostate Cancer
    Nicholas M. Donin and Robert E. Reiter
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 177-182; DOI: https://doi.org/10.2967/jnumed.117.191874

Focus on Molecular Imaging

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    In Vivo Imaging of Pro- and Antitumoral Cellular Components of the Tumor Microenvironment
    Anne Helfen, Johannes Roth, Tony Ng and Michel Eisenblaetter
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 183-188; DOI: https://doi.org/10.2967/jnumed.117.198952

Editorial

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    Responsible Radiomics Research for Faster Clinical Translation
    Martin Vallières, Alex Zwanenburg, Bodgan Badic, Catherine Cheze Le Rest, Dimitris Visvikis and Mathieu Hatt
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 189-193; DOI: https://doi.org/10.2967/jnumed.117.200501

Oncology

  • Clinical

    • BRIEF COMMUNICATION

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        Early Evaluation of Response Using 18F-FDG PET Influences Management in Gastrointestinal Stromal Tumor Patients Treated with Neoadjuvant Imatinib
        Sheima Farag, Lioe-Fee de Geus-Oei, Winette T. van der Graaf, Frits van Coevorden, Dirk Grunhagen, Anna K.L. Reyners, Pieter A. Boonstra, Ingrid Desar, Hans Gelderblom and Neeltje Steeghs
        Journal of Nuclear Medicine February 1, 2018, 59 (2) 194-196; DOI: https://doi.org/10.2967/jnumed.117.196642
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      Improved Estrogen Receptor Assessment by PET Using the Novel Radiotracer 18F-4FMFES in Estrogen Receptor–Positive Breast Cancer Patients: An Ongoing Phase II Clinical Trial
      Michel Paquette, Éric Lavallée, Serge Phoenix, René Ouellet, Helena Senta, Johan E. van Lier, Brigitte Guérin, Roger Lecomte and Éric E. Turcotte
      Journal of Nuclear Medicine February 1, 2018, 59 (2) 197-203; DOI: https://doi.org/10.2967/jnumed.117.194654
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      The Impact of Adding Sentinel Node Biopsy to Extended Pelvic Lymph Node Dissection on Biochemical Recurrence in Prostate Cancer Patients Treated with Robot-Assisted Radical Prostatectomy
      Nikolaos Grivas, Esther M.K. Wit, Teele Kuusk, Gijs H. KleinJan, Maarten L. Donswijk, Fijs W.B. van Leeuwen and Henk G. van der Poel
      Journal of Nuclear Medicine February 1, 2018, 59 (2) 204-209; DOI: https://doi.org/10.2967/jnumed.117.195644
  • Basic

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      Dynamic 18F-FDG PET Lymphography for In Vivo Identification of Lymph Node Metastases in Murine Melanoma
      Hannah Lockau, Volker Neuschmelting, Anuja Ogirala, Antoni Vilaseca and Jan Grimm
      Journal of Nuclear Medicine February 1, 2018, 59 (2) 210-215; DOI: https://doi.org/10.2967/jnumed.117.196303
    • FEATURED BASIC SCIENCE ARTICLE

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        Preclinical Development of CD38-Targeted [89Zr]Zr-DFO-Daratumumab for Imaging Multiple Myeloma
        Anchal Ghai, Dolonchampa Maji, Nicholas Cho, Chantiya Chanswangphuwana, Michael Rettig, Duanwen Shen, John DiPersio, Walter Akers, Farrokh Dehdashti, Samuel Achilefu, Ravi Vij and Monica Shokeen
        Journal of Nuclear Medicine February 1, 2018, 59 (2) 216-222; DOI: https://doi.org/10.2967/jnumed.117.196063

Theranostics

  • Clinical

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      Long-Acting Somatostatin Analog Therapy Differentially Alters 68Ga-DOTATATE Uptake in Normal Tissues Compared with Primary Tumors and Metastatic Lesions
      Narjess Ayati, Sze Ting Lee, Rasoul Zakavi, Kunthi Pathmaraj, Louai Al-Qatawna, Aurora Poon and Andrew M. Scott
      Journal of Nuclear Medicine February 1, 2018, 59 (2) 223-227; DOI: https://doi.org/10.2967/jnumed.117.192203
    • INVITED PERSPECTIVE

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        PSMA PET: Transformational Change in Prostate Cancer Management?
        Hossein Jadvar and Leslie K. Ballas
        Journal of Nuclear Medicine February 1, 2018, 59 (2) 228-229; DOI: https://doi.org/10.2967/jnumed.117.203604
    • FEATURED ARTICLE OF THE MONTH

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        68Ga-PSMA-11 PET/CT Mapping of Prostate Cancer Biochemical Recurrence After Radical Prostatectomy in 270 Patients with a PSA Level of Less Than 1.0 ng/mL: Impact on Salvage Radiotherapy Planning
        Jeremie Calais, Johannes Czernin, Minsong Cao, Amar U. Kishan, John V. Hegde, Narek Shaverdian, Kiri Sandler, Fang-I Chu, Chris R. King, Michael L. Steinberg, Isabel Rauscher, Nina-Sophie Schmidt-Hegemann, Thorsten Poeppel, Philipp Hetkamp, Francesco Ceci, Ken Herrmann, Wolfgang P. Fendler, Matthias Eiber and Nicholas G. Nickols
        Journal of Nuclear Medicine February 1, 2018, 59 (2) 230-237; DOI: https://doi.org/10.2967/jnumed.117.201749
  • Translational

    • FEATURED TRANSLATIONAL SCIENCE ARTICLE

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        Immunohistochemical Validation of PSMA Expression Measured by 68Ga-PSMA PET/CT in Primary Prostate Cancer
        Nadine Woythal, Ruza Arsenic, Carsten Kempkensteffen, Kurt Miller, Jan-Carlo Janssen, Kai Huang, Marcus R. Makowski, Winfried Brenner and Vikas Prasad
        Journal of Nuclear Medicine February 1, 2018, 59 (2) 238-243; DOI: https://doi.org/10.2967/jnumed.117.195172
  • Basic

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      Targeted Molecular Radiotherapy of Pediatric Solid Tumors Using a Radioiodinated Alkyl-Phospholipid Ether Analog
      Dana C. Baiu, Ian R. Marsh, Alexander E. Boruch, Ankita Shahi, Saswati Bhattacharya, Justin J. Jeffery, Qianqian Zhao, Lance T. Hall, Jamey P. Weichert, Bryan P. Bednarz and Mario Otto
      Journal of Nuclear Medicine February 1, 2018, 59 (2) 244-250; DOI: https://doi.org/10.2967/jnumed.117.193748

Cardiovascular

  • Clinical

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      Determination of the Heart-to-Mediastinum Ratio of 123I-MIBG Uptake Using Dual-Isotope (123I-MIBG/99mTc-Tetrofosmin) Multipinhole Cadmium-Zinc-Telluride SPECT in Patients with Heart Failure
      Tanguy Blaire, Alban Bailliez, Fayçal Ben Bouallegue, Dimitri Bellevre, Denis Agostini and Alain Manrique
      Journal of Nuclear Medicine February 1, 2018, 59 (2) 251-258; DOI: https://doi.org/10.2967/jnumed.117.194373
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      Prognostic Value of 123I-BMIPP SPECT in Patients with Nonischemic Heart Failure with Preserved Ejection Fraction
      Hidenobu Hashimoto, Rine Nakanishi, Sunao Mizumura, Yukiko Hashimoto, Yuriko Okamura, Shunsuke Kiuchi, Junichi Yamazaki and Takanori Ikeda
      Journal of Nuclear Medicine February 1, 2018, 59 (2) 259-265; DOI: https://doi.org/10.2967/jnumed.117.195743
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      Clinical Molecular Imaging of Chemokine Receptor CXCR4 Expression in Atherosclerotic Plaque Using 68Ga-Pentixafor PET: Correlation with Cardiovascular Risk Factors and Calcified Plaque Burden
      Desiree Weiberg, James T. Thackeray, Guenter Daum, Jan M. Sohns, Saskia Kropf, Hans-Juergen Wester, Tobias L. Ross, Frank M. Bengel and Thorsten Derlin
      Journal of Nuclear Medicine February 1, 2018, 59 (2) 266-272; DOI: https://doi.org/10.2967/jnumed.117.196485

Special Contribution

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    Clinical Quantification of Myocardial Blood Flow Using PET: Joint Position Paper of the SNMMI Cardiovascular Council and the ASNC
    Venkatesh L. Murthy, Timothy M. Bateman, Rob S. Beanlands, Daniel S. Berman, Salvador Borges-Neto, Panithaya Chareonthaitawee, Manuel D. Cerqueira, Robert A. deKemp, E. Gordon DePuey, Vasken Dilsizian, Sharmila Dorbala, Edward P. Ficaro, Ernest V. Garcia, Henry Gewirtz, Gary V. Heller, Howard C. Lewin, Saurabh Malhotra, April Mann, Terrence D. Ruddy, Thomas H. Schindler, Ronald G. Schwartz, Piotr J. Slomka, Prem Soman and Marcelo F. Di Carli
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 273-293; DOI: https://doi.org/10.2967/jnumed.117.201368

Neurology

  • Clinical

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      Brain Perfusion Imaging Under Acetazolamide Challenge for Detection of Impaired Cerebrovascular Reserve Capacity: Positive Findings with 15O-Water PET in Patients with Negative 99mTc-HMPAO SPECT Findings
      Güliz Acker, Catharina Lange, Imke Schatka, Andreas Pfeifer, Marcus A. Czabanka, Peter Vajkoczy and Ralph Buchert
      Journal of Nuclear Medicine February 1, 2018, 59 (2) 294-298; DOI: https://doi.org/10.2967/jnumed.117.195818
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      18F-Flortaucipir PET/MRI Correlations in Nonamnestic and Amnestic Variants of Alzheimer Disease
      Ilya M. Nasrallah, Yin Jie Chen, Meng-Kang Hsieh, Jeffrey S. Phillips, Kylie Ternes, Grace E. Stockbower, Yvette Sheline, Corey T. McMillan, Murray Grossman and David A. Wolk
      Journal of Nuclear Medicine February 1, 2018, 59 (2) 299-306; DOI: https://doi.org/10.2967/jnumed.117.194282
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      Impact of Endothelial 18-kDa Translocator Protein on the Quantification of 18F-DPA-714
      Catriona Wimberley, Sonia Lavisse, Vincent Brulon, Marie-Anne Peyronneau, Claire Leroy, Benedetta Bodini, Philippe Remy, Bruno Stankoff, Irène Buvat and Michel Bottlaender
      Journal of Nuclear Medicine February 1, 2018, 59 (2) 307-314; DOI: https://doi.org/10.2967/jnumed.117.195396
    • BRIEF COMMUNICATION

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        Test–Retest Reliability of the SERT Imaging Agent 11C-HOMADAM in Healthy Humans
        Vikram Adhikarla, Boadie W. Dunlop, Nashwa Jarkas, Mark M. Goodman, Helen Mayberg, Michael J. Owens and Jonathon A. Nye
        Journal of Nuclear Medicine February 1, 2018, 59 (2) 315-319; DOI: https://doi.org/10.2967/jnumed.117.196915

Inflammation/Infectious Disease

  • Clinical

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      68Ga-Pentixafor PET/CT Imaging of Chemokine Receptor CXCR4 in Chronic Infection of the Bone: First Insights
      Caroline Bouter, Birgit Meller, Carsten O. Sahlmann, Wieland Staab, Hans J. Wester, Saskia Kropf and Johannes Meller
      Journal of Nuclear Medicine February 1, 2018, 59 (2) 320-326; DOI: https://doi.org/10.2967/jnumed.117.193854
  • Translational

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      Evaluation of the Lysophosphatidic Acid Receptor Type 1 Radioligand 11C-BMT-136088 for Lung Imaging in Rhesus Monkeys
      Jean-Dominique Gallezot, Nabeel B. Nabulsi, Daniel Holden, Shu-Fei Lin, David Labaree, Jim Ropchan, Soheila Najafzadeh, David J. Donnelly, Kai Cao, Samuel Bonacorsi, Jon Seiders, Jeffrey Roppe, Wendy Hayes, Yiyun Huang, Shuyan Du and Richard E. Carson
      Journal of Nuclear Medicine February 1, 2018, 59 (2) 327-333; DOI: https://doi.org/10.2967/jnumed.117.195073
  • Basic

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      68Ga-NOTA-Functionalized Ubiquicidin: Cytotoxicity, Biodistribution, Radiation Dosimetry, and First-in-Human PET/CT Imaging of Infections
      Thomas Ebenhan, Mike M. Sathekge, Thabo Lengana, Michel Koole, Olivier Gheysens, Thavendran Govender and Jan R. Zeevaart
      Journal of Nuclear Medicine February 1, 2018, 59 (2) 334-339; DOI: https://doi.org/10.2967/jnumed.117.200048

Radiochemistry

  • Basic

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      64Cu-Labeled Repebody Molecules for Imaging of Epidermal Growth Factor Receptor–Expressing Tumors
      Ayoung Pyo, Misun Yun, Hyeon Sik Kim, Tae-Yoon Kim, Joong-jae Lee, Jung Young Kim, Sunwoo Lee, Seong Young Kwon, Hee-Seung Bom, Hak-Sung Kim, Dong-Yeon Kim and Jung-Joon Min
      Journal of Nuclear Medicine February 1, 2018, 59 (2) 340-346; DOI: https://doi.org/10.2967/jnumed.117.197020

Errata

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    Erratum
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 346;
  • You have access
    Erratum
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 346;

Book Reviews

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    Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases
    E. Edmund Kim
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 347; DOI: https://doi.org/10.2967/jnumed.117.206698

Letters to the Editor

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    DNA Repair After Exposure to Ionizing Radiation Is Not Error-Free
    James R. Duncan, Michael R. Lieber, Noritaka Adachi and Richard L. Wahl
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 348; DOI: https://doi.org/10.2967/jnumed.117.197673
  • You have access
    Reply: DNA Repair After Exposure to Ionizing Radiation Is Not Error-Free
    Jeffry A. Siegel, Bill Sacks, Charles W. Pennington and James S. Welsh
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 349; DOI: https://doi.org/10.2967/jnumed.117.198804
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    Regarding “18F-GP1, a Novel PET Tracer Designed for High-Sensitivity, Low-Background Detection of Thrombi”
    Abass Alavi, Thomas J. Werner, Søren Hess and Poul Flemming Høilund-Carlsen
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 350-351; DOI: https://doi.org/10.2967/jnumed.117.200378
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    Reply: Regarding “18F-GP1, a Novel PET Tracer Designed for High-Sensitivity, Low-Background Detection of Thrombi”
    Andrew Stephens
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 351; DOI: https://doi.org/10.2967/jnumed.117.203687

Abstracts

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    AACR/SNMMI State-of-the-Art Molecular Imaging in Cancer Biology and Therapy: Abstracts
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 352-378; DOI: https://doi.org/10.2967/jnm592abs

SNMMI Newsline

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    2017 SNMMI Highlights Lecture: Oncology, Part 2
    Wolfgang Weber
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 9N-17N;
  • You have access
    Survey of Programs About the ABR 16-Month Nuclear Radiology Pathway for Diagnostic Radiology Residents
    Jay A. Harolds
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 16N-17N;
  • You have access
    SNMMI Leadership Update: Strengthening Outreach to Patients and the Medical Community
    Virginia Pappas
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 18N;
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    From The Literature
    Journal of Nuclear Medicine February 1, 2018, 59 (2) 19N-20N;
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In this issue

Journal of Nuclear Medicine: 59 (2)
Journal of Nuclear Medicine
Vol. 59, Issue 2
February 1, 2018
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author

Issue highlights

  • 68Ga-PSMA-11 PET/CT Mapping of Prostate Cancer Biochemical Recurrence After Radical Prostatectomy in 270 Patients with a PSA Level of Less Than 1.0 ng/mL: Impact on Salvage Radiotherapy Planning
  • Preclinical Development of CD38-Targeted [89Zr]Zr-DFO-Daratumumab for Imaging Multiple Myeloma
  • Immunohistochemical Validation of PSMA Expression Measured by 68Ga-PSMA PET/CT in Primary Prostate Cancer
  • Why Targeting PSMA Is a Game Changer in the Management of Prostate Cancer
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      • BRIEF COMMUNICATION
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      • FEATURED BASIC SCIENCE ARTICLE
  • Theranostics
    • Clinical
      • INVITED PERSPECTIVE
      • FEATURED ARTICLE OF THE MONTH
    • Translational
      • FEATURED TRANSLATIONAL SCIENCE ARTICLE
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  • Cardiovascular
    • Clinical
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  • Neurology
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      • BRIEF COMMUNICATION
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  • Long-Term Follow-up and Outcomes of Retreatment in an Expanded 50-Patient Single-Center Phase II Prospective Trial of 177Lu-PSMA-617 Theranostics in Metastatic Castration-Resistant Prostate Cancer
  • First-in-Human Assessment of 11C-LSN3172176, an M1 Muscarinic Acetylcholine Receptor PET Radiotracer
  • Impact of 68Ga-PSMA-11 PET/CT on Staging and Management of Prostate Cancer Patients in Various Clinical Settings: A Prospective Single-Center Study
  • Tau PET imaging with 18F-PI-2620 in Patients with Alzheimer Disease and Healthy Controls: A First-in-Humans Study
  • Radiation Dosimetry in 177Lu-PSMA-617 Therapy Using a Single Posttreatment SPECT/CT Scan: A Novel Methodology to Generate Time- and Tissue-Specific Dose Factors
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