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Research ArticleOncology

Combined VLA-4–Targeted Radionuclide Therapy and Immunotherapy in a Mouse Model of Melanoma

Jaeyeon Choi, Wissam Beaino, Ronald J. Fecek, Kellsye P.L. Fabian, Charles M. Laymon, Brenda F. Kurland, Walter J. Storkus and Carolyn J. Anderson
Journal of Nuclear Medicine December 2018, 59 (12) 1843-1849; DOI: https://doi.org/10.2967/jnumed.118.209510
Jaeyeon Choi
1Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania
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Wissam Beaino
2Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania
3VU University Medical Center, Department of Radiology and Nuclear Medicine, Amsterdam, The Netherlands
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Ronald J. Fecek
4Department of Dermatology, University of Pittsburgh, Pittsburgh, Pennsylvania
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Kellsye P.L. Fabian
5Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania
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Charles M. Laymon
2Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania
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Brenda F. Kurland
6Department of Biostatistics, University of Pittsburgh, Pittsburgh, Pennsylvania
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Walter J. Storkus
1Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania
4Department of Dermatology, University of Pittsburgh, Pittsburgh, Pennsylvania
5Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania
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Carolyn J. Anderson
1Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania
2Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania
7Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania; and
8Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania
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Article Information

vol. 59 no. 12 1843-1849
DOI 
https://doi.org/10.2967/jnumed.118.209510
PubMed 
29959213

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication February 6, 2018
  • Accepted for publication May 31, 2018
  • Published online December 3, 2018.

Article Versions

  • previous version (June 29, 2018 - 11:05).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2018 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Jaeyeon Choi1,
  2. Wissam Beaino2,3,
  3. Ronald J. Fecek4,
  4. Kellsye P.L. Fabian5,
  5. Charles M. Laymon2,
  6. Brenda F. Kurland6,
  7. Walter J. Storkus1,4,5 and
  8. Carolyn J. Anderson1,2,7,8
  1. 1Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania
  2. 2Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania
  3. 3VU University Medical Center, Department of Radiology and Nuclear Medicine, Amsterdam, The Netherlands
  4. 4Department of Dermatology, University of Pittsburgh, Pittsburgh, Pennsylvania
  5. 5Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania
  6. 6Department of Biostatistics, University of Pittsburgh, Pittsburgh, Pennsylvania
  7. 7Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania; and
  8. 8Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania
  1. For correspondence or reprints contact: Carolyn J. Anderson, Department of Medicine, University of Pittsburgh, 3501 Fifth Ave., Room 10020, Pittsburgh, PA 15260. E-mail: andersoncj{at}upmc.edu
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Journal of Nuclear Medicine: 59 (12)
Journal of Nuclear Medicine
Vol. 59, Issue 12
December 1, 2018
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Combined VLA-4–Targeted Radionuclide Therapy and Immunotherapy in a Mouse Model of Melanoma
Jaeyeon Choi, Wissam Beaino, Ronald J. Fecek, Kellsye P.L. Fabian, Charles M. Laymon, Brenda F. Kurland, Walter J. Storkus, Carolyn J. Anderson
Journal of Nuclear Medicine Dec 2018, 59 (12) 1843-1849; DOI: 10.2967/jnumed.118.209510

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Combined VLA-4–Targeted Radionuclide Therapy and Immunotherapy in a Mouse Model of Melanoma
Jaeyeon Choi, Wissam Beaino, Ronald J. Fecek, Kellsye P.L. Fabian, Charles M. Laymon, Brenda F. Kurland, Walter J. Storkus, Carolyn J. Anderson
Journal of Nuclear Medicine Dec 2018, 59 (12) 1843-1849; DOI: 10.2967/jnumed.118.209510
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Keywords

  • melanoma
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  • targeted radionuclide therapy
  • VLA-4
  • PET imaging
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